1. Clinical research of transcatheter arterial chemoembolization combined with three dimensional conformal radiotherapy and hyperthermia for primary hepatic carcinoma
Shurui LU ; Jundong CAI ; Guijie LIANG ; Jing LIU ; Zhenya WANG
Chinese Journal of Primary Medicine and Pharmacy 2018;25(17):2189-2192,c17-1
Objective:
To investigate the effect of transcatheter arterial chemoembolization(TACE) combined with three dimensional conformal radiotherapy(3-DCRT) and hyperthermia on inoperable primary hepatic carcinoma.
Methods:
This study retrospectively analyzed 96 patients with hepatic carcinoma in the Third Hospital of Chengde between 2014 and 2017 who received TACE or combined therapy (TACE combined with 3-DCRT and hyperthermia). Kaplan-Meier curve was used to compare the overall survival(OS) of the two groups.
Results:
There were 50 cases in the combined therapy group, 46 cases in the TACE group.The effective rate of the combined therapy group was 76.1%, and that of TACE group was 45.6%, the difference was statistically significant(
2. Clinic features and prognostic analysis for T1 esophagus cancer
Zhe YU ; Xiaomin LI ; Mei HUAI ; Guijie LU ; Chong WANG ; Quanyu WANG ; Qingyi LIU
Chinese Journal of Oncology 2018;40(4):268-273
Objective:
To investigate relationship between the clinicopathological features and prognosis of T1 esophageal carcinoma.
Methods:
Data from 212 T1 primary esophageal cancer patients, who underwent radical surgery in The Fourth Hospital of Hebei Medical University from Jan 2001 to Dec 2009 were enrolled. There were 148 males and 64 females. There were 91 patients with stage pT1a and 121 patients with stage pT1b.
Results:
The survival of the 212 patients was 27~108 months, and the median survival was 80.8 months. The 1, 3, and 5 year survival rates of patients with stage T1a were 100%, 97.8% and 94.5%, respectively, and the median survival was 86.8 months. The 1, 3, and 5 year survival rates of patients with stage T1b were 100%, 95.9% and 74.4%, respectively, and the median survival was 76.2 months. The rate of lymph node metastasis in 121 patients with stage T1b was 26.4% (32/121). The lymph node metastasis rates in patients with stage sm1, sm2 and sm3 were 11.6% (3/26), 15.0% (6/40) and 41.8% (23/55), respectively. There was no significant difference in lymph node metastasis between stage sm1 patients and stage sm2 patients (