1.Toxicity and efficacy of post-operative chemoradiotherapy for gastric cancer
Guichao LI ; Zhen ZHANG ; Weilie GU ; Weigang HU ; Yingqiang SHI ; Jin LI
Chinese Journal of Radiation Oncology 2008;17(3):203-205
Objective To evaluate the toxicity and efficacy of post-operative chemoradiotherapy for gastric cancer. Methods Forty-five gastric cancer patients treated with post-operative radiation ± concurrent chemotherapy were retrospectively analyzed. Among them, 14 were female and 31 were male. The median age was 54 (30-72) years. Pathology stages were IB-IV. Radiotherapy of doses from 45 Gy/25fx to 55 Gy/30fx was delivered to the tumor bed and regional lymph nodes with 3D conformal or IMRT technology.Concurrent chemotherapy agent was fluorouracil or capacitabine. Results All patients except 2 (4%)completed radiotherapy as planned. The most common acute toxicities were hematologic and gastrointestinal effects. The incidence of the patients was 56% with mild nausea/vomiting,71% and 7% with grade Ⅰ / Ⅱ and Ⅲ leucopenia, and 38% with grade Ⅰ/Ⅱ hypodynamia and anepithymia. The 1-year overall survival,relapse-free survival and local control rates were 87% ,82% and 95%, respectively. Conclusions Postoperative chemoradiation for patients with locally advanced gastric cancer is tolerable. Our study shows the advantage of post-operative chemoradiation for local control. However,further prospective randomized trial is needed to validate the efficacy.
2.Ergonomics methodology,application framework and research prospect for unmanned aerial vehicle lifecycle
Shihui ZHANG ; Guichao SHI ; Chuanyan FENG ; Kun JI
Space Medicine & Medical Engineering 2024;35(3):180-186
With the rapid growth of the utilization of Unmanned Aerial Vehicle(UAV),the corresponding ergonomics problems are becoming increasingly prominent.Based on a review of the literature and industrial practice,ergonomics evaluation methods for UAV lifecycle are investigated in this study.The ergonomics research scope of UAV and the ergonomics evaluation method of UAV lifecycle are emphasized;The ergonomics analysis framework of UAV lifecycle is proposed,and the ergonomics practice method under key lifecycle stage of UAV development for typical applications is explained;In addition,combined with the development of intelligent technology,the research prospect of ergonomics on UAV is put forward.This study can provide some reference for the development of UAV from the perspective of ergonomics design and evaluation.