2.Efficacy of phacoemulsification auxiliary hookinterred the anterior chamber treated failure of glaucoma combined with cataract surgery
Ying-Ying, ZHANG ; Li-Gui, ZHANG ; Yue-Qin, QI
International Eye Science 2016;16(11):2145-2147
AIM: To explorethe therapeutic efficacy of treating cataract phacoemulsification remove combined with trabeculectomy early postoperative failure with open sclera flap recanalization by phacoemulsification auxiliary hook interred the anterior chamber.
METHODS:Twenty-seven cases ( 27 eyes ) of glaucoma combined cataract surgery(3mo) in the early failure were treated with that the phacoemulsification auxiliary hook into anterior chamber under the original sclera flap, open from the inside have adhesion of the sclera flap. Postoperative follow-up 12mo, the intraocular pressure and best corrected visual acuity were observed.
RESULTS: The postoperative follow- up was 12mo. There were functional filtering bleb in 14(52%) eyes; and the IOP was below 21mmHg in 17 eyes(63%) without any anti- glaucoma drug, and in 7 eyes ( 26%) with 1 - 2 categories of lower intraocular pressure( IOP) drugs, and 3 eyes(11%), failure and the success rate was 89% after 12mo. Average intraocular pressure after 1wk, 1mo, 3mo, 6mo and 12mo were(7. 1±4. 3) mmHg,(10. 5±5. 1) mmHg,(15. 1±4. 8 ) mmHg, ( 16. 8±5. 2 ) mmHg, ( 17. 3±5.1 ) mmHg, significantly lower than the IOP preoperatively(30. 2±6. 8) mmHg (P<0. 01). Average visual acuity ( all of the following were best corrected vision) after 1wk, 1mo, 3mo, 6mo and 12mo was(0. 32±0. 52),(0. 52±0. 42),(0. 55±0. 39),(0. 53±0. 47),(0. 54±0. 42 ). Postoperative 1wk visual acuity deeper than preoperative( 0. 46 ± 0. 44 ) ( P < 0. 05 ), more than all improved compared with preoperative ( P < 0. 05 ). Postoperative anterior chamber bleeding in 5(19%) eyes, all absorbed itself in 3 to 5 days; ciliochoroidal detachment in 7 ( 26%) eyes, except one case need operate, others were conservative treatment to heal. Postoperative continuous low intraocular pressure concurrent macular edema was 1 eyes(4%), 4mo healed after treatment.
CONCLUSION: It is a safe and effective method thattreating phacoemulsification cataract remove combined with trabeculectomy early postoperative failure with open sclera flap recanalization by phacoemulsification auxiliary hook interred the anterior chamber.
3.Genetic analysis of bronchial hyperresponsiveness and serum total IgE of asthma pedigree
Qin GUI ; Guisheng QIAN ; Zengwei ZHAO ; We ZHANG
Journal of Third Military Medical University 2003;0(22):-
Objective To study the genetics pattern of bronchial hyperresponsiveness and serum total IgE in asthma pedigree. Methods Twenty-eight asthma families were collected, including 124 individuals, 72 with asthma and 52 without. Forty-five normal subjects of three generations without consanguinity among one another, 22 male and 23 female, were chosen as controls, excluding those with family history of asthma and hypersensitivity. Serum total IgE by ELISA and bronchial hyperresponsiveness (BHR) were detected in asthma pedigree members. Genetics pattern of BHR and serum total IgE was analysed. Results The frequency distribution of BHR was bimodal. Individuals with higher level of total IgE occupied 40 of BHR-affected. Conclusion BHR may be controlled by a single major gene. BHR and total IgE may be under separate genetic control.
6. Nucleoside analogues against hepatitis B virus: Research advances
Journal of International Pharmaceutical Research 2013;40(1):8-13
Hepatitis B virus is a serious hazard to human health, and the research and development of anti-hepatitis B virus drugs have become hot topics in the world. Based on the literature at home and abroad, the recent progress of anti-hepatitis B virus agents is reviewed in this paper, including structure characteristics, antiviral mechanism, in vitro and in vivo activity evaluation, and clinical application. Furthermore, the opportunities and challenges for anti-hepatitis B virus drugs in China are prospected.
7.Pharmacognostical study on four origin plants of folk medicine Sikuaiwa.
Yong LIU ; Qi ZHANG ; Yu-jiao PENG ; Zhi-gui WU ; Gui-bing LIN ; Yan-qin XU ; Yong-ming LUO
China Journal of Chinese Materia Medica 2015;40(21):4177-4181
In order to develop characteristic folk medicine resources in Jiangxi, a pharmacognostical study was systematically performed for four different origin plants of Sikuaiwa, the result of study provides the microscopic features of powder and tissue of the crude drug. The research provided reference for the identification of Sikuaiwa, as well as a theoretical basis for the further development and the formulation of quality standards.
Magnoliopsida
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anatomy & histology
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chemistry
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growth & development
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Medicine, Traditional
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Plants, Medicinal
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anatomy & histology
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chemistry
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growth & development
9.Human papillomavirus and p53 protein immunoreactivity in condylomata acuminatum and squamous cell carcinoma of penis
ZHANG XIN-HUA ; SUN GUI-QIN ; YANG YU ; ZHANG TAI-HE
Asian Journal of Andrology 2001;3(1):75-77
To determine the immunoreactive pattem of human papillomavirus (HPV) antigen and p53 protein in condylomata acuminatum (CA) and squamous cell carcinoma (SCC) of penis. Methods: Immunohistochemistry for HPV and p53 were performed in 40 specimens of formalin fixed, paraffin embedded tissues using a polyclonal (rabbit) antibody against HPV and a monoclonal (mouse) antibody against human p53 protein. Twenty one cases of CA and nineteen cases of SCC were examined. Results: HPV antigen was detected in all 21 CA and 2 penile SCC. p53 protein overexpression was observed in 12 of 19 (63%) SCC in which 6 cases were strong positive. Five of 21 CA (24%)showed low-grade p53 protein overexpression. Conclusion: CA is related to HPV infection and some cases show p53 protein low-grade overexpression. In contrast, p53 protein overexpression is common in penile SCC, which is seldom related to HPV infection.
10.Study of effects of complex aerobatics on serum insulin, cortisol and angiotensin II.
Ming Gao LI ; She Zhen QIN ; Gui Xi MA ; Lang En XU ; Xin Hua ZHANG
Korean Journal of Aerospace and Environmental Medicine 1993;3(1):112-118
No abstract available.
Angiotensin II*
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Angiotensins*
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Hydrocortisone*
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Insulin*