OBJECTIVETo optimize the herb processing process for the total contains of psoralen and isopsoralen and the rate of extract in Psoralea corylifolia by micro-wave herb processing.

METHODThe contains of psoralen and isopsoralen was obtained by HPLC. The micro-wave herb processing process was optimized by the way of uniform design and contour map.

RESULTThe optimum process was:20% as salt concentration, 4h as immerse time, micro-wave strength as strong, 270 seconds as micro-wave time. The absolute error of the predicted value from the models were smaller than 6% and 0. 3% respectively.

CONCLUSIONThe regression models are notable and reasonable, which can forecast results precisely.

Chromatography, High Pressure Liquid ; methods ; Fruit ; chemistry ; Furocoumarins ; analysis ; Microwaves ; Plants, Medicinal ; chemistry ; Psoralea ; chemistry ; Regression Analysis ; Reproducibility of Results ; Technology, Pharmaceutical ; instrumentation ; methods