The cold wave is one of the common meteorological factors which related to occurrence of disease,and growth of animals and plants.Due to seasonal restrictions and differences of the main indicators of each cold wave,it is difficult to be consistent when studying the relationship between cold wave and disease,cold wave and growth of animals and plants.In order to make the experimental results more objective and credible,it is necessary to simulate a cold spell artificially.The key technique for simulating a cold wave is to control the temperature manually,so that can achieve the standard of cold wave.Nowadays,the equipments for cold wave simulating include "artificial climate chamber" or "climate simulator",which can be used in the study of the relationship between cold wave and disease,cold wave and growth of animals and plants.The intelligent artificial climate chambers can successfully create an experimental environment that similar to the natural cold wave,thus the study of the relationship between temperature and growth or incidence of animals and plants is no longer restricted by seasonal restrictions,and maintains the consistency between different artificial cold waves,which is beneficial for analysis and judgment.However,the intelligent artificial climate chambers still needs to be further improved in terms of expanding space and manual control of air pressure and humidity.