Purpose To investigate clinicopathological features,diagnosis and differential diagnosis of tubular carcinoma of the breast.Methods Morphological observation and immunohistochemistry were applied in 29 cases of tubular carcinoma of the breast, and the literatures were also reviewed.Results The tumors were composed of open tubules, infiltrating haphazardly in the cellular desmoplastic stroma. The neoplastic tubules were enclosed by a single layer of epithelial cells with insignificant atypia or rare mitoses.The tumors were often associated with lobular neoplasm, columnar cell lesion, ductal atypical hyperplasia or carcinoma in situ. Immunostaining displayed that myoepithelial cells were absent or incomplete.Conclusions Tubular carcinoma of the breast is a peculiar subtype of breast carcinoma with good prognoses, which is easily confused with microglandular adenosis, radial sclerosing lesions,or low grade invasive ductal carcinoma.Immunohistochemistry is useful for the differential diagnosis.

Objective To study the hip angle characteristics in hemiplegic gait.Methods Gait analysis was performed in 20 subjects with hemiplegia and 20 healthy subjects and the hip joint angle of all subjects was analyzed.Results The hip joint angle of affected-side lower limb of hemiplegic gait showed significant differences between 20 subjects with hemiplegia and 20 healthy subjects on hip flextion at heel-contact,maximum extension in stand phase,flextion toe-off,maximum flexion in swing phase and total excursion on sagittal plane.Conclusion The research on the characteristics of hemiplegic gait is helpful to make clinical assessment and treatment planning.

ObjectiveTo study the reliability and sensitivity of the gait analysis system based on digital video and image processing.Methods20 healthy subjects were assessed twice by the same doctor having one-week interval to investigate intraobserver reliability, they were also assessed twice separately by two doctors to investigate interobserver reliability. Gait parameters of affected limb of 20 hemiplegic patients were compared with 20 healthy subjects to investigate the sensitivity of this system.ResultsThere were high correlations in all the parameters between the two assessments. The parameters of the patients were significantly different from those of the controls.ConclusionThe system is sufficiently repeatable and sensitive in the assessment of gait.

本文就康复概念的“泛化”现象 ,提出了一些看法。对康复科学、康复系统工程及其对工程技术的需求 ,进行了分析探讨。结论 :康复工程的广义内涵是理清边界、拾遗补缺、设置接口、实现系统集成 ,利用现代工程技术的手段和方法促进残疾者的全面康复。

Objective To investigate the relative motion between the femoral component and the tibial insert through the technology of fluoroscopy and digital model.Methods Sixteen female patients (16 knees) with knee osteoarthritis were performed TKA (GENESIS Ⅱ) from July 2007 to June 2008.The mean age was 66.4 years (range from 56 to 76 years).All patients were followed up 48 months to 60 months,with the mean of 56±3 months.The postoperative clinical function was evaluated by Knee Society Score (KSS).To match the digital model to the imaging data of fluoroscopy using 2D-3D automatic registration technology and reconstruct motion of the knee after TKA.The movement of contact position between femoral medial and lateral condyle and tibial insert and tibial internal rotation during flexion were measured.The contact time and range between femoral cam and tibial post were analyzed.Results The cases were statistically improved in KSS postoperatively,knee score was 93±5 and function score 88±13.The range of movement for femoral medial condyle was 8.5±2.5 mm,and the lateral condyle was 9.5±4.8 mm,the range of tibial internal rotation was 2.5°±8.4°.The contact of cam and post was observed after 30°-40° flexion of the knee,and the range was 8.0±1.8 mm.The greater tilting angle of the tibial plateau was,the later contact between cam and post happened.Conclusion The kinematics of tibiofemoral joint after TKA is different from the kinematics of normal knee.With knee flexion within 10°-30°,femoral medial condyle moves forward.When flexion is greater than 40°,medial and lateral condyle begins rollback.The time of contact of cam and post is relative to tibial prosthesis slope.

Objective:To study a new positioning method of elbow external fixation rotation axis,and to evaluate its feasibility.Methods:Four normal adult volunteers and six Sawbone elbow models were brought into this experiment.The kinematic data of five elbow flexion were collected respectively by opti-cal positioning system.The rotation axes of the elbow joints were fitted by the least square method.The kinematic data and fitting results were visually displayed.According to the fitting results,the average moving planes and rotation axes were calculated.Thus,the rotation axes of new kinematic methods were obtained .By using standard clinical methods,the entrance and exit points of rotation axes of six Sawbone elbow models were located under X-ray.And The kirschner wires were placed as the representatives of rotation axes using traditional positioning methods.Then,the entrance point deviation,the exit point de-viation and the angle deviation of two kinds of located rotation axes were compared.Results:As to the four volunteers,the indicators represented circular degree and coplanarity of elbow flexion movement tra-jectory of each volunteer were both about 1 mm.All the distance deviations of the moving axes to the ave-rage moving rotation axes of the five volunteers were less than 3 mm.All the angle deviations of the mo-ving axes to the average moving rotation axes of the five volunteers were less than 5 °.As to the six Saw-bone models,the average entrance point deviations,the average exit point deviations and the average angle deviations of two different rotation axes determined by two kinds of located methods were respective-ly 1.697 2 mm,1.838 3 mm and 1.321 7°.All the deviations were very small.They were all in an ac-cep-table range of clinical practice.Conclusion:The values that represent circular degree and coplanari-ty of volunteer's elbow single curvature movement trajectory are very small.The result shows that the elbow single curvature movement can be regarded as the approximate fixed axis movement.The new method can replace the traditional method in accuracy.It can make up the deficiency of the traditional fixed axis method.

ObjectiveTo study normal gait characteristics of healthy adults in different age groups.Methods90 healthy adults were divided into three groups according to their ages. It was 20～39 year group, 40～59 year group and 60～70 year group. They received a gait analysis with the gait analysis system based on digital video and image processing which could provide temporal-spatial parameters and kinematic parameters. The gait data of the three groups were compared. Relationships between gait speed and other gait parameters were investigated.ResultsThere were statistically significant differences in some parameters among three groups. Gait speed was significantly correlated with stride time, stride length, stance time (%), cadence, maximum flexion of hip and knee in swing phase.ConclusionThe normal gait patterns of healthy adult established with the gait analysis system based on digital video and image processing can be used as the base line to compare with abnormal gait.

The article describes the development of an Internet-based tele-rehabilitation system for patients with cognitive deficits,including overall idea,design and structure of the system,role-based authorization of operations for the patients and doctors and the procedures for patients' receiving rehabilitation treatment through the system.It is a new and convenient mode for rehabilitation service delivery to patients with cognitive deficits.Implementation of the Internet-based tele-cognitive rehabilitation system is helpful to the patients who live far from hospitals and have difficulty seeing doctors due to physical impairments,and is helpful to solving the problem with lack of medical staffs specialized in cognitive rehabilitation.Furthermore,it will also profit pushing out the spread and development of cognitive rehabilitation in China.

Edge detection is an absolutely necessary step in medical image processing, and the use of differential operators to detect edge is one of the most common and effective methods. In this paper are analyzed the frequency features of the Roberts operator, Prewitt operator, Sobel operator and Laplacian operator from the viewpoint of frequency domain, and it is proposed that the frequency features of the differential operators should be considered when differential operator is being used and/or constructed. Because edge detection operator is sensitive to the edge type, the appropriate operator should be adopted in different edge type detection. Finally, the importance and necessity of selecting edge detection operator are validated in the MRI image edge processing.
Algorithms ; Brain ; pathology ; Humans ; Image Enhancement ; methods ; Image Interpretation, Computer-Assisted ; methods ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging ; Pattern Recognition, Automated ; methods