1.Forensic Medical Assessment for Neurologic Erectile Dysfunction:58 Case Reports
Guangyou ZHU ; Yan SHEN ; Hongguo LIU
Journal of Forensic Medicine 2015;(5):369-372
To introduce the approaches and procedures of neurologic erectile dysfunction (ED ) assessm ent in our institute, and evaluate the neurologic investigation by m aking an analysis of 58 cases. D iagnostic criteria of neurologic ED: nervous system injuries or diseases, abnorm al clinical sym ptom s and signs, electrophysiological abnorm alities of nervous system , abnorm al results of nocturnal penile tum escence and rigidity (N PTR ) (penis rigidity <60% and lasting tim e <10 m inutes). In the group of 20 patients w ith the injuries of the brain, spinal cord or spinal root nerves, pudendal cortical som atic evoked potential (PCSEP), sacral reflex latency (SRL),pudendal-to-corticalm otorevoked potential (PCM EP), penile sym-pathetic skin responses (PSSR ) and N PTR show ed abnorm ality by 45%, 20%, 20%, 85% and 85%, re-spectively. In 38 patients w ith the injuries of pelvic fracture w ith urethra break, PCSEP, SRL, PCM EP, PSSR and N PTR show ed abnorm ality by 24% , 5% , 20% , 92% and 66% , respectively. In the form er, 35% w ere identified to have severe ED , and 50%, m oderate ED;in the latter, 21%, to have severe ED , 13%, m edium ED , and 37%, light ED . The approaches and procedures w ere proved to possess excellent specificity and reliability in the assessm ent of neurological ED .
2.Study on nuclear DNA content of colorectal carcinoma and its prognostic significance
Yinggui ZHU ; Fengxuan NIU ; Guangyou HE
Journal of Third Military Medical University 1988;0(06):-
The DNA content was quantitively determined in 30 specimens of colorectal carcinoma including 15 cases of tubular adenocarcinoma (TAC.5 cases each of grade Ⅰ,Ⅱ and Ⅲ respectively) ,5 cases of papillary adenocarcinoma (PAO.5 cases of mucoid adenocarcinoma (MAC) and 5 cases of signet-ring cell carcinoma (SCO),and 5 specimens of norma! colomic nucosa with mi-crospectro-photometry.The average DNA contents of different tissues were as follows:Normal colonic mucosa:13.54The difference of DNA contents of various types of carcinoma with normal mucosa,and that of TAC-Ⅰ and SCC with TAC-Ⅲ,PAC and MAC was statistically very significant (P
3.Long-Term Trend of Bone Development in the Contemporary Teenagers of Chinese Han Nationality
Yahui WANG ; Chongliang YING ; Lei WAN ; Guangyou ZHU
Journal of Forensic Medicine 2012;28(4):269-274
Objective To further improve the accuracy of bone age identification using the time of secondary ossification center appearance and epiphyseal fusion of 7 joints to estimate the age of living individuals.Methods DR films were taken from 7 parts including sternal end of clavical and the left side of shoulder,elbow,carpal,hip,knee and ankle joints of 1709 individuals who came from eastern China,central China and southern China,whose ages were between 11.0 and 20.0 years.From those 7 joints 24 osteal loci were selected as bone age indexes,which could better reflect age growth of teenagers.The characteristics of secondary ossification center appearance and epiphyseal fusion were observed,and the mean and age range of secondary ossification center appearance and epiphyseal fusion were calculated.Results The fusion time of the 24 epiphyses were advanced at different degrees,the most obvious epiphyses the sternal end of clavicle,scapular acromial end,distal end of the radius,distal end of the ulna,iliac crest,ischial tuberosity,the upper and lower end of tibia and fibula.The appearance time of sternal end of clavicle,scapular acromial end,iliac crest and ischial tuberosity epiphyses were all found to be after the age of 12,and the female's age,approximately 1year ahead of schedule in comparison with the male's.Conclusion The relevant forensic information and data for bone age identification should be updated every 10-15 years so as to provide accurate and objective evidence for court testimony,conviction and sentencing.
4.Automated Assessment of Developmental Levels of Epiphysis by Support Vector Machine
Yahui WANG ; Zishen WANG ; Hua WEI ; Lei WAN ; Chongliang YING ; Guangyou ZHU
Journal of Forensic Medicine 2014;(6):422-426
Objective To realize the autom ated assessm ent of the levels of epiphysis of distal radius and ulna by support vector m achine (SVM). Methods The X-ray film s of the leftwrist jointswere taken from 140 teenagers aged from 11 to 19 years old as training sam ples. The levels of epiphysis of distal radius and ulnawere divided into five developm ental levels. Each level contained 28 sam ples. A nother 35 cas-eswere selected as independent verifying sam ples. SVM classification m odels of the five developm ental levels of epiphysis of distal radius and ulnawere established. The internal cross validationwas m ade by leave one out cross validation (LOOCV ),while the external validationwas m ade by histogram of orient-ed gradient (HOG), and then the accuracy (PA ) of testing resultswas calculated, respectively. Results The PA of SVM, LOOCV and HOG of distal radius epiphyseal levelwere 100%, 78.6%, and 82.8%, respec-tively;whereas the PA of SVM, LOOCV and HOGof distal ulna epiphyseal levelwere 100.0%, 80.0%and 88.6%, respectively. Conclusion The SVM -based autom atic m odels of the growth stage of distal ra-dius and ulna appear to have certain feasibility, and m ay provide a foundation for software developm ent of bone age assessm ent by forensic medicine.
5.Study advances in analgesic management in severe patients after neurosurgery
Qingjing MA ; Yan RAO ; Xiwen ZHU ; Hai CHEN ; Guoqing ZENG ; Guangyou DUAN ; Jie CHEN
Chongqing Medicine 2024;53(1):145-148
Analgesia is an important link in the treatment of severe patients after neurosurgery and plays a vital role in improving the prognosis of the patients.Understanding the status quo and influencing fac-tors of pain in severe patients after neurosurgery helps to predict the occurrence of pain,which is crucial for determining the new pain assessment methods and auxiliary analgesic methods and developing novel analgesic drugs.This paper reviews the pain status,pain evaluation and analgesic methods of severe patients after neuro-surgery in recent years so as to understand the pain management current status of the patients with severe neurological conditions and provide reference for the medical staff to implement the analgesic programs.