【Objective】 To explore the whole blood collectionstatusat street fixed blood donation sites in different time periods and regions, among different populations with different recruitment methods in Chengdu. 【Methods】 The whole blood donation data at street fixed blood donation sites in Chengdu from 2014 to 2018 were collected, and then statistically analyzed in terms of weekdays/ weekends/holidays, the urban/suburban counties, the first/ repeated blood donation and local/ non-local household registration.On weekdays, blood donors were recruited at fixed blood donation sites while on weekends/holidays they were recruited via on-site recruitment combined with "computer-network-mobile phone" mode. 【Results】 There are 36 fixed blood donation sites in Chengdu, among which 22 were in suburban counties and 14 in urban area.There were more blood drives on weekdays than weekends / holidays every year, with fewer average daily collection on weekdays in comparison with weekends/holidays(P<0.05). The collection units on weekends/holidays were high in January, July, August and December, medium in March, April, June, September and October, and low in February, May and November (P<0.05). There were more blood drives in urban area than suburban counties on weekends/holidays, with fewer average daily collection in urban areain comparison with suburban counties. From 2014 to 2018, the total collection units at street fixed blood donation sites in suburban counties increased year by year (P<0.05). The proportion of first-time blood donors in urban area (59.62%) was significantly higher than that in suburban counties (43.45%) (P<0.05). The proportion of non-local registered blood donors in urban area (53.39%) was significantly higher than that in suburban counties (20.39%)(P<0.05). The number of text messages we sent for recruitment on weekends and holidays and the number of blood donors who responded increased year by year (P<0.05). 【Conclusion】 Whole blood collection at street fixed blood donation sites in Chengdu suburban counties on weekends and holidays was enhanced by using information interactive mode as "computer-network-mobile phone", which allows blood station managers to schedule blood collection in different periods and formulate reasonable blood collection plan.