Objective To investigate the situation and development trend of adolescent mental health diathesis, and explore the differences and influencing factors among students with different features.Methods 338 adolescents were tested with the Adolescent Mental Health Diathesis Scale. Results ①Except the self levels,there was significant differences in other levels and sublevels of the mental health diathesis between college( ( adaption(64.17 ±7.12) interpersonal(58.70 ±7.13 ) personality( 127.72 ± 14.41 ) motive power system( 109.34 ±11.76) cognitive style(43.76 ±4.24) copying style( 106.14 ± 10.33 ) ) and middle school students( ( adaption (68.27 ±5.86) interpersonal(64.78 ±5.25) personality( 135.72 ± 10.52) motive power system( 129.79 ±10.12) cognitive style(49.86 ± 4.70 ) copying style ( 124.77 ± 9.80 ) ), boys and girls, students in cities and countries, with different levels of parents'education or economic of family.②Correlation and reegression analysis showed that the form and development trend of mental health diathesis was influenced by several factors.Conclusion In general, the state of adolescent mental health diathesis is good in Jinan.Different groups of adolescents have diverse styles on the scales and dimensions of mental health diathesis.

Objective:To evaluate the efficacy of 1-year subcutaneous immunotherapy (SCIT) with dust mites in polysensitized allergic rhinitis (AR) patients and to analyze the serological markers associated with clinical response.Methods:A retrospective analysis of data from 69 polysensitized AR patients who completed 1-year SCIT with dust mites from Oct 2020 to Mar 2022 in Shandong Provincial ENT Hospital was conducted. The median patient age was 21 years, including 41 males and 28 females. The changes in symptoms and serum IgE, IgG4 assessed before and after treatment were evaluated. The differences in serological markers between effective and ineffective groups were analyzed. Multivariate regression analysis was used to investigate the predictors of clinical response. SPSS 22.0 software was used for data processing.Results:After immunotherapy, there was a significant reduction in symptom scores and a substantial improvement in the quality of life of polysensitized AR patients (all P<0.001). Dust mite specific IgG4 (sIgG4) significantly increased and dust mite specific IgE (sIgE)/sIgG4 significantly decreased (all P<0.05). sIgE, total IgE (tIgE), sIgE/tIgE and sIgE/sIgG4 were significantly lower in ineffective group than those in effective group (all P<0.05). The clinical response of SCIT related only to dust mite sIgE ( r=0.29, P=0.036), and sIgE≥53.86 kU/L had the best sensitivity (77.78%) and specificity (57.89%) to predict effective SCIT in polysensitized AR patients. Conclusions:One-year dust mite SCIT is effective for polysensitized AR patients. Pre-treatment serum dust mite sIgE≥53.86 kU/L may play a role in predicting clinical response of dust mite SCIT in polysensitized AR patients.