1.Childhood trauma and non-suicidal self-injury in college students: chain mediating effects of rejection sensitivity and experiential avoidance
Chinese Journal of Behavioral Medicine and Brain Science 2023;32(1):50-55
Objective:To explore the effect of childhood trauma on non-suicidal self-injury and the chain mediating effect of rejection sensitivity and experiential avoidance.Methods:From June 2021 to April 2022, totally 1 130 college students were investigated with childhood trauma questionnaire-short form(CTQ-SF), the tendency to expect rejection scale, acceptance and action questionnaire-2nd edition(AAQ-Ⅱ) and Ottwa self-injury inventory(OSI). SPSS 25.0 and Mplus 8.0 software were used for descriptive analysis, Spearman correlation analysis, structural equation model construction and Bootstrap mediation effect test.Results:Correlation analysis showed that childhood trauma (34.64±8.25), rejection sensitivity (58.02±9.54), experiential avoidance (23.90±7.96) and non-suicidal self-injury (0(0, 1)) were all significantly positively correlated with each other( r=0.163-0.532, all P<0.01). Structural equation model showed that empirical avoidance played a partial mediating effect between childhood trauma and non-suicidal self-injury in college students, with an effect size of 0.045(95% CI=0.013-0.084). Rejection sensitivity and experiential avoidance played a chain mediating effect between childhood trauma and non-suicidal self-injury in college students, with an effect size of 0.017(95% CI=0.005-0.035). Conclusion:Childhood trauma can directly predict non-suicidal self-injury in college students, and it can also indirectly predict non-suicidal self-injury through the partial mediation effect of experiential avoidance and the chain mediation effect of rejection sensitivity and experiential avoidance.
2.Relationship of subjective well-being with personality trait and self-efficacy in policemen
Guanghui NIE ; Jianbo LIU ; Zhenyu MA
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(12):1105-1108
Objective To explore the relationships of subjective well-being with personality trait and self-efficacy in policemen.Methods Totally 329 policemen from 3 prisons were assessed with General Well-Being Schedule (GWBS),Eysenck Personality Questionnaire (EPQ) and General Self-Efficacy Scale (GSES).The relationship between subjective well-being and personality traits,self-efficacy of policemen was analyzed using correlation analysis,variance analysis,regression analysis and structural equation modeling.Results The personality of extroverted stability had the highest score in GSE (2.74 ± 0.56) and GWB (88.89±11.90),while the introverted instability had the lowest(GSE:(2.19±0.46);GWB:(67.38±13.79)).Psychoticism(2.45± 1.72) was negatively correlated with GWB (78.24± 15.32) (r=-0.19,P<0.01),neuroticism(5.07±3.31) was negatively correlated with GSE (2.50±0.57) and GWB (r=-0.38,-0.60,all P<0.0l),while introversion-extroversion(8.13±2.86) was positively correlated with GSE and WGB (r=0.26,0.29,all P<0.01).Structural equation model showed that neuroticism negatively influenced GWB (γ =-0.610,P<0.01),and introversion-extroversion positively influenced GWB (γ=0.169,P<0.05).Self-efficacy had partial mediating effect on relationship between neuroticism and GWB as well as the relationship between introversion-extroversion and GWB.Conclusions There is a high correlation between neuroticism and GWB.Self-efficacy plays a mediating role on relationship between personality trait and GWB.It can promote GWB of policemen by enhancing their self-efficacy.
3.Correlations among childhood trauma, autistic traits and dysexecutive functions in college students
Jingbo GONG ; Yuqiong HE ; Xilong CUI ; Yajie ZHANG ; Xueyun ZHANG ; Jianbo LIU ; Guanghui NIE
Chinese Mental Health Journal 2018;32(1):58-63
Objective:To explore the relations among childhood trauma,autistic traits and dysexecutive functions in college students.Methods:Totally 2757 college students were assessed with the Childhood Trauma Questionnaire (CTQ).Sixty-three college students were randomly selected as the abused group according to the subscale cutoff point of CTQ Scale defined by Bernstein,and 93 students were randomly selected from students without history of childhood trauma as the control group.They were assessed with the Self-Rating Depression Scale (SDS),Autism Spectrum Quotient (AQ) and Dysexecutive Questionnaire (DEX) to measure depression,autistic traits and abnormality of executive functions,respectively.The individuals from the top and below 27% of CTQ and AQ scores were defined as higher or lower-level different types of abused group and higher or lower-level autistic traits group,respectively.Results:The differences of DEX scores between higher or lower-level four types of CTQ (emotional abuse,physical abuse,sexual abuse,emotional neglect and physical neglect) and between higher or lower-level autistic traits group were significant (Ps <0.05).DEX scores in all higher-level groups were higher than all lower-level groups.Regression analysis showed that DEX score could be positively predicted by scores of emotional abuse,AQ and SDS (β =0.17-0.32,P <0.05).SDS score was a mediator between scores of emotional abuse and DEX,and between scores of autistic traits and DEX (95% confidence interval were 0.05-0.32 and 0.07-0.55,respectively).Conclusion:Childhood trauma and autistic traits may positively predict dysexecutive function,and depression may play a mediating role between emotional abuse and dysexecutive function,and between autistic traits and dysexecutive function.
4.The relationship between self-esteem, social support and life satisfaction of urban elderly residents
Lina TAN ; Guanghui NIE ; Xin WU ; Zhenghua TANG
Chinese Journal of Behavioral Medicine and Brain Science 2018;27(4):352-355
Objective To explore the difference in demographic variables of the self-esteem of Nanning elderly residents and its relationship with social support,life satisfaction.Methods A sample of 496 elderly lived at Nanning were assessed with self-esteem scale(SES),social support rating scale (SSRS) and life satisfaction index A scale (LISA).Results There were significant differences in overall self-esteem,positive self-esteem and negative self-esteem among different groups of marriage(t=2.209,2.127,-1.839),educational level (t=-2.332,-2.047,2.164),health (F=8.552,3.668,-12.736),economy (F =13.465,14.865,-7.643) and interests(F=8.552,3.668,-12.736) (t=2.860,2.394,-2.785);P<0.05).Social support (40.13 ± 6.29) could positively predict positive self-esteem (3.04± 0.27) and negatively predict negative self-esteem(2.29±0.23) (β=0.280,-0.195,P<0.01).Positive self-esteem could positively predict life satisfaction and negative self-esteem could negatively predict life satisfaction(12.58±3.90) (β=0.397,-0.443,P<0.01).The intermediary effect of positive self-esteem,negative self-esteem between social support and life satisfaction were significantly(P<0.01).Conclusion Self-esteem has partial intermediary role between social support and life satisfaction.
5.The mediation role of self-esteem between workplace bullying and mental health among nurses:the moderating effect of self-efficacy
Guanghui NIE ; Pingping ZENG ; Yan DENG ; Bo WEI
Chinese Journal of Behavioral Medicine and Brain Science 2017;26(3):262-265
Objective To investigate the impact of workplace bullying,general self?efficacy,self?es?teem on mental health of nurses. Methods With random sampling,450 nurses from six hospitals in Nanning of Guangxi were selected to complete questionnaire survey. Results 34.7% of nurses were reported to have been subjected to bullying at their workplace. Workplace bullying(23.78±6.94) showed significantly nega?tive relationship with mental health(36.63±4.53)( r=-0.32, P<0.01),while general self?efficacy(26.86± 4.82) and self?esteem(30.62±4.08) showed significantly positive correlations with mental health( r=0.45, 0.44, P<0.01). Workplace bullying had a significantly negative effect on mental health ( β=-0.25, P<0.01) ,and the relationship was affected by general self?efficacy and self?esteem. Conclusion Workplace bullying can influent nurses' mental health through self?esteem and the relationship is moderated by general self?efficacy.
6.Analysis of Moral Psychology of Contemporary Medical Professionals in China:Based on Network Medical Negative Incidents
Weiling CAO ; Jianghong DU ; Guanghui NIE
Chinese Medical Ethics 2017;30(10):1232-1236
Problems such as frequent medical disputes and lack of mutual trust between doctors and patients re -quire us to pay more attention to the medical professionals ' moral ethics practice .By means of deepening the un-derstanding of medical professionals ' moral psychology , it expected to promote medical ethics education and medi-cal management smoothly , meanwhile , alleviate medical disputes .This paper analyzed medical professionals ' com-ments on the Selfie in Operating Room Incident using a qualitative study .By analyzing their moral psychology be-hind these comments , it depicted three mental representations of medical professionals ' ethics practice , namely conflict,responsibility and concerns .
7.Effect of ditching for drain on control of Oncomelania hupensis snail in beaches of Dongting Lake
Wangyuan WEI ; Kaimin BU ; Kailin WEI ; Zhihong LUO ; Guanghui REN ; Xianglin CHEN ; Jianmin YI ; Yu LIU ; Yang XIANG ; Kewen TANG ; Jianhui YAN ; Meng XIA ; Liang DING ; Xianjiang LU ; Dongsong NIE ; Yaun LI
Chinese Journal of Schistosomiasis Control 2015;(3):241-245
Objective To evaluate the effect of ditching for drain on the control of the breed of Oncomelania hupensis snails in beaches of Dongting Lake. Methods From November,2009 to November,2012,an O. hupensis snail infested beach of the Yueyang jail and an O. hupensis snail infested beach of Junshan District were selected as research fields in the eastern Dongting Lake area,and the former,as the intervention field,was performed with the ditching for drain by excavators and the latter,as the control field,was not. Results Before the project implemented,the average soil moisture contents on the beaches in dry seasons of the two fields were both about 35.56%. After the project implemented,in the intervention field,the average soil mois?ture content was 26.53%which was significantly lower than that(35.56%)in the control field(F=6.53,P<0.05). The under?ground water levels in different heights in the intervention field were lower than those in the control field (χ2 = 33.33,P <0.05). Before the project implemented,the natural death rates of the snails were 0.98%and 0.89%in the two research fields re?spectively(P>0.05),and after the project implemented(in 2012),no adult and young snails were found in the interventional field,but in the control field,the average densities of living snails and young snails were 29.37 snails/0.1 m2 and 213±108.45 snails/0.1 m2 respectively. Conclusion The intervention of ditching for drain can decrease the soil moisture contents quickly and change the ecological condition,therefore,can control the breed of O. hupensis snails in the beaches of Dongting Lake.
8.Clinical characteristics of human infection with a novel avian-origin influenza A(H10N8) virus.
Wei ZHANG ; Jianguo WAN ; Kejian QIAN ; Xiaoqing LIU ; Zuke XIAO ; Jian SUN ; Zhenguo ZENG ; Qi WANG ; Jinxiang ZHANG ; Guanghui JIANG ; Cheng NIE ; Rong JIANG ; Chengzhi DING ; Ran LI ; Peter HORBY ; Zhancheng GAO
Chinese Medical Journal 2014;127(18):3238-3242
BACKGROUNDNovel influenza A viruses of avian-origin may be the precursors of pandemic strains. This descriptive study aims to introduce a novel avian-origin influenza A (H10N8) virus which can infect humans and cause severe diseases.
METHODSCollecting clinical data of three cases of human infection with a novel reassortment avian influenza A (H10N8) virus in Nanchang, Jiangxi Province, China.
RESULTSThree cases of human infection with a new reassortment avian influenza A(H10N8) virus were described, of which two were fatal cases, and one was severe case. These cases presented with severe pneumonia that progressed to acute respiratory distress syndrome (ARDS) and intractable respiratory failure.
CONCLUSIONThis novel reassortment avian influenza A (H10N8) virus in China resulted in fatal human infections, and should be added to concerns in clinical practice.
Aged ; Antiviral Agents ; therapeutic use ; Female ; Fluoroquinolones ; therapeutic use ; Humans ; Imipenem ; therapeutic use ; Influenza A Virus, H10N8 Subtype ; drug effects ; pathogenicity ; Influenza, Human ; complications ; diagnosis ; drug therapy ; Male ; Middle Aged ; Oseltamivir ; therapeutic use
9.Application of sandwich teaching method in teaching of medical psychology
Guanghui NIE ; Junduan WU ; Zhenghua TANG
Chinese Journal of Medical Education Research 2014;(2):165-168
Objective To explore the teaching effect of sandwich teaching in medical psychol-ogy. Methods Totally 101 preventive medicine majors of five-year program were divided into two groups:control group(n=52) and experimental group(n=49). Students in control group were taught by traditional teaching while those in experimental group by sandwich teaching method. Teaching qualities were evaluated by final exam and questionnaire. Exam scores were expressed as x±s and were ana-lyzed by t test. Questionnaine results were expressed as number of people and percentage. Results Scores of experimental group in multiplechoice, case study and final grade (30.347±4.171, 32.031± 2.781, 74.296±5.642, respectively) were better than those of control group (28.520±4.443, 28.760± 4.305, 70.010±7.783, respectively), with significant differences between two groups(P<0.05 for all). But there was no significant difference between two groups in short-answer questions score (11.918± 2.431, 12.731±2.523, respectively)(P>0.05). More than 80.0% students in experimental group thought sandwich teaching improved their communication collaborative capacity , logical thinking ability and problem solving ability, etc. Conclusions With satisfactory teaching effect, sandwich teaching promotes teaching quality.
10.Basic experimental and clinical research on peritoneal dialysis in the past 16 years.
Fuyou LIU ; Youming PENG ; Shalin ZOU ; Guanghui LING ; Jing NIE ; Wenbin TANG ; Xun ZHOU ; Shaobin DUAN ; Jun LI ; Yinghong LIU ; Hong LIU ; Fang YUAN ; Li XIAO ; Li ZHUO ; Junxiang CHEN ; Xing CHEN ; Meichu CHENG ; Jianling ZHU ; Xiaoping ZHU ; Ji' an LUO ; Min FAN ; Hao ZHANG ; Lin SUN
Journal of Central South University(Medical Sciences) 2009;34(3):269-276
To summarized the experiences from our basic experimental and clinical research on peritoneal dialysis. In the past 16 years, peritoneal fibrosis rat models and rabbit models of peritonitis were first established successfully in our laboratory in China. Peritoneal mesothelial cells were also separated and identificated. Besides, we assessed the biocompatibility of peritoneal dialysis fluid and analyzed the molecular mechanism of peritoneal mesothelial cell injury. We demonstrated the key role of transforming growth factor-beta1 (TGF-beta1), connective tissue growth factor (CTGF) and peroxisome proliferative activated receptor-gamma (PPAR-gamma) in the pathogenesis of peritoneal fibrosis, as well as their regulation of molecular mechanism. Furthermore, we transfected the plasmids encoding TGF-beta1-shRNA or pCTGF-shRNA into peritoneal cells and tissues by nanocarrier technologies. In clinical research, the positioning of peritoneal dialysis catheters, peritoneal dialysis treatment modalities and the prevention and treatment of its complications were studied. The characteristics and mechanism of solute transport in peritoneal dialysis was also explored.
Animals
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Connective Tissue Growth Factor
;
metabolism
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Fibrosis
;
physiopathology
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prevention & control
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Humans
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Kidney Failure, Chronic
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metabolism
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therapy
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Peritoneal Dialysis
;
methods
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Peritoneal Dialysis, Continuous Ambulatory
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adverse effects
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Peritoneum
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pathology
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Rabbits
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Rats
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Retrospective Studies
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Tissue Adhesions
;
physiopathology
;
prevention & control
;
Transforming Growth Factor beta
;
metabolism

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