Objective:To investigate the effect of of simvastatin on bone formation and bone mineral density(BMD) during the retention after orthodontic tooth movement. Methods:Orthodontic tooth movement of upper first molar was performed in 40 rats with coil spring for 21 days. 40 rats were randomly allocated into 5 groups: basic control group,negative control group and 3 simvastatin groups(2.5 mg?kg-1, 5.0 mg?kg-1 and 10.0 mg?kg-1respectively).Rats in basic control group were killed when appliances were removed after 21 days.The experimental groups were administered simvastatin daily from 1 day before appliances removed for 4 weeks.The negative control group received the isotonic saline as control.4 weeks later all animals were anesthetized and killed. Level of serum Ca and P in blood, ALP, BGP and BMD were monitored.Results:①Between experimental groups and the negative control group, in amounts of ALP and BGP,the anterior were higher than the posterior (P0.05). ②The alveolar near the maxillary first molar,BMD of the basic control group was the highest(P

Objective To establish an equation between canine and other permanent teeth,and probe a new method to predict the sum of the mesiodistal diameters of unerupted permanent canines.Methods Samples consisted of 118 dental casts were obtained from Chinese patients(50 males,68 females,respectively).Mesiodistal tooth diameters were measured by a vernier caliper.GAS was used to establish the equation between canine and other permanent teeth,and compared with stepwise regression analysis.Those were modelling samples that optimized equations coefficient(112 samples).Others were inspection samples(6 samples).Results The equation between canine and other permanent teeth was established.MU=0.0511U1+0.2164U2+0.2780U4+0.0407U5+0.2853U6+0.8321①;ML=0.2998U1+0.1294U2+0.3912U4+0.0088U5+0.0791U6+0.9839②;FU=0.1419U1+0.1741U2+0.3258U4+0.0412U5+0.093U6+1.7355③;FL=0.2796U1+0.3750U2+0.2968U4+0.0268U5+0.0043U6+0.6030④.Compared with stepwise regression analysis,the mean error of precision by GAS was less(P

[Objective]To analyze the relation of age and sex with the incidence of physical examinees with osteoporosis and low bone mass of vertebras.[Method]Quantitative CT(QCT) was used to examine and analyze the lumbar bone mineral density in 575 physical examinees.The data was analyzed by statistical software SAS 9.0.[Result]Bone mineral density(BMD)decreased with age after 50 years old.The occurrence rates of osteoporosis were 56.34% for females at 50-59 years,87.80% at 60-69 years,97.22% at 70-79 years and 100% at 80-89 years,25.44% for males at 50-59 years,50.64% at 60-69 years,66.66% at 70-79 years,and 90.91% at 80-89 years.[Conclusion]The incidence of osteoporosis is positively related with the age.The occurrence rate of osteoporosis increases with increasing age.It is obviously higher in females than in males.

[Objective] To evaluate the clinical value of diagnosing osteoporosis with vertebra bone mineral density(BMD) by measurement with quantitative computed tomography (QCT) . [ Method] BMD in of lumbar vertebrae (L<,1～4>)were measured by QCT in 53 healthy middleaged persons or elderly persons (group A) and 68 osteoporosis patients ( groupB) . [Result] BMD in group A declined obviously as age increasing with significant differences (P<0. 01) . In group B,all 68 patients showed osteoporosis according to the diagnostic standard of BMD≤x -2. OSD. Sixty patients showed osteoporosis ifthe diagnostic standard was set to BMD ≤ x -2. 5SD. The BMD values of different age group was lower than the bone quantityblock values. [Conclusion] As a method for diagnosing osteoporosis, QCT has advantages of high sensitation, being precise,being reproducible and is easy for applying. It would be more practical and could decrease mis - diagnosing if the diagnosticstandard was BMD≤x-2.OSD.

The enzymatic synthesis of endomorphins were carried out by immobilized papain on sodium alginate-chitosan (IPSAC). The reaction has been carried out in two steps. First, Trp-Phe-NH2 was obtained by Boc-Trp-OH coupling with Phe-NH2 using IPSAC catalyst in microaqueous acetonitrile system with a 27.8 % yielding as determined by high performance liquid chromatography (HPLC). The catalytic properties of IPSAC were examined by studying the dependence of pH, ionic strength, solution content, reaction temperature,enzyme loading and reaction time over the yields. The results of orthogonal experiments indicated that pH was the most significant factor that influenced this synthesis. Second, Boc-Tyr-Pro-OMe and Trp-Phe-NH2 were suspended into the microaqueous acetonitrile to produce Tyr-Pro-Trp-Phe-NH2 (endomorphin-1) with a 35.2% yield.

OBJECTIVETo study the genetic relationship of Astragalus membranaceus var. mongholicus in different producing area and provide theoretical basis for the evaluation of Astragalus germplasm resources.

METHODThrough quence-related amplified polymorphism (SRAP) analysis, the systematic diagram of genetic relationship was constructed by UPGMA method.

RESULTA total of 141 SRAP markers were scored. By the use of UPGMA cluster analysis with genetic distance, Astragalus could be divided into two provenance plots of Gansu and Shanxi.

CONCLUSIONThe genetic differentiation among populations of A. membranaceus var. mongholicus is remarkable. SRAP marker could be efficiently used for the study of the genetic relationship of Astragalus.

Astragalus Plant ; classification ; genetics ; Astragalus membranaceus ; genetics ; DNA, Plant ; analysis ; Drugs, Chinese Herbal ; classification ; Genetic Markers ; genetics ; Phylogeny ; Polymorphism, Genetic ; RNA, Ribosomal, 18S ; genetics

OBJECTIVETo investigate the distribution and host plants of Cynomorium songaricum, and provide a scientific basis for the artificial cultivation of C. songaricum and protect the ecological environment in the sandy area.

METHODSpecimens of C. songaricum in growing area was collected and accessed according to relevant literature and identified.

RESULTThe results showed that a new host plant of C. songaricum-Peganum multisectum was found.

CONCLUSIONA new host plant of C. songaricum, Peganum multisectum was reported, and it is provide the necessary nutrition for normal growth of C. songaricum.

China ; Cynomorium ; anatomy & histology ; physiology ; Ecosystem ; Peganum ; anatomy & histology ; physiology

As the transportation of O2 and CO2 inside human body is an integrated aspect of Qi-blood transportation, a hemodynamic model is established based on the analysis of the respiratory and circulation system. The results of such model show that the abnormality of the circulatory and respiratory parameters always lead to a reduction of Po2 (O2 pressure) in tissue fluid, and then a Lung Qi-Deficiency Syndrome (QDS). This model can be used to quantitatively explain, to some extent, the physiological phenomena of Lung QDS, and could combine all the discoveries of in clinical researches, on Lung QDS. The measurement of Po2 in tissue fluid as an index to analyze Lung QDS is in accordance with TCM and TMM (the theory of modern medicine). This model may provide a new approach in clinical research of Lung QDS.
Hemodynamics ; Lung Diseases ; physiopathology ; Medicine, Chinese Traditional ; Models, Biological ; Qi ; Respiratory Mechanics

Based on the morphology and function of lymphatic vessel, and on the achievements of researches in the regulatory mechanism of lymphatic circulation, we fully considered the dynamic interaction of blood, interstitial fluid and lymph fluid; then we imitated and used Sungawa's method of analyzing the heart output, and finally set up a dynamic model for describing lymphatic circulation. Comparison of our calculating results with the data from Ikomi's experiment showed that they were identical, thus indicating that our model is of value in explaining the dynamic mechanism of lymphatic circulation. In this paper is especially calculated the relationship between lymph flow and massage frequency, which is useful for analyzing the effect of massage on the lymph flow rate with respect to this model.
Animals ; Computer Simulation ; Endothelium, Lymphatic ; cytology ; physiology ; Humans ; Lymph ; physiology ; Lymphatic Vessels ; physiology ; Models, Biological ; Nonlinear Dynamics ; Pressure ; Rabbits ; Rheology