1.Low-magnitude vibration promotes osteogenesis of osteoblasts in ovariectomized osteoporotic rats via the estrogen receptor
Guangguang ZHU ; Xiaoqin YU ; Jirui WEN ; Mingyue BAO ; Min TANG ; Jingge WANG ; Xueling HE ; Liang LI
Journal of Biomedical Engineering 2020;37(5):825-833
The purpose of this study was to investigate the effect of low-magnitude vibration on osteogenesis of osteoblasts in ovariectomized rats with osteoporosis via estrogen receptor α(ERα). The mRNA expression of osteogenic markers were examined with qRT-PCR, based on which the optimal vibration parameter for promoting osteogenesis was determined (45 Hz × 0.9 g, g = 9.8 m/s
Animals
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Cell Differentiation
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Estrogen Receptor alpha/genetics*
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Female
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Osteoblasts
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Osteogenesis
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Osteoporosis
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Ovariectomy
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Rats
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Vibration