OBJECTIVES: To explore the efficacy of DSA-guided intrathecal drug delivery system combined with Zi Wu Liu Zhu Acupoint Therapy for management of cancer pain and provide reference for its standardized clinical application. Methods and. RESULTS: Recommendations were formulated based on literature review and expert group discussion, and consensus was reached following expert consultation. The consensus recommendations are comprehensive, covering the entire treatment procedures from preoperative assessment and preparation, surgical operation process, postoperative management and traditional Chinese medicine treatment to individualized treatment planning. The study results showed that the treatment plans combining traditional Chinese with Western medicine effectively alleviated cancer pain, reduced the use of opioid drugs, and significantly improved the quality of life and enhanced immune function of the patients. Postoperative follow-up suggested good treatment tolerance among the patients without serious complications. CONCLUSIONS The formulated consensus is comprehensive and can provide reference for clinicians to use DSA-guided intrathecal drug delivery system combined with Zi Wu Liu Zhu Acupoint Therapy. The combined treatment has a high clinical value with a good safety profile for management of cancer pain.
Humans ; Medicine, Chinese Traditional ; Cancer Pain/therapy* ; Drugs, Chinese Herbal/therapeutic use* ; Drug Delivery Systems ; Pain Management/methods* ; China

Objective To study the clinical efficacy of combination of Modified Lianpo Decoction and standard quadruple therapy for Hp-related gastritis of damp-heat syndrome of spleen and stomach. Methods Based on the principles of random, contrast, and double-blind, 118 cases of Hp-related gastritis of damp-heat syndrome of spleen and stomach were randomly divided into western medicine group (39 cases) and combined Chinese and western medicine group (79 cases). The western medicine group was treated with standard quadruple therapy (PPI + bismuth + two kinds of antibiotics), and the combined Chinese and western medicine group with Modified Lianpo Decoction additionally for two weeks. The clinical efficacy, TCM symptom scores, and eradication rate of Hp were observed by electronic gastroscope, rapid urease test, and pathologic examination before and one month after the treatment, respectively. Results The clinical effective rate of the western medicine group was 76.9% (30/39), while that of the combined Chinese and western medicine group was 94.9%(75/79), with statistical significance (P<0.05). The Hp eradication rate of the western medicine group was 87.2%(34/39), and that of the combined Chinese and western medicine group was 97.5% (77/79), with statistical significance (P<0.05). TCM symptom scores regarding damp-heat syndrome of the spleen and stomach of the combined Chinese and western medicine group were significantly better than those of the western medicine group (P<0.05). Conclusion The clinical efficacy, TCM symptoms, and eradication rate of Hp can be significantly improved by combination of Modified Lianpo Decoction and standard quadruple therapy in the treatment for patients with Hp-related gastritis of damp-heat syndrome of spleen and stomach.