Objective To evaluate the recovery of island ?-cell function through different terms of continuous subcutaneous insulin infusion(CSII)in diabetic patients with failure of oral hypoglycemic agents(OHA).Methods The 48 diabetic patients with OHA failure were divided into group A(10 cases,7-day CSII),group B(18 cases,14-day CSII)and group C(20 cases,28-day CSII).Results Compared with group A,the daily administration of basic dose and premeal supplementary dose of insulin at targeted glucose level were decreased in group B and C(P