1.Research progress of the relation between A20 and cancers
Yaoqi WANG ; Xianying MENG ; Guang CHEN ; Qiang ZHANG ; Jiabin HAN
Chinese Journal of Endocrine Surgery 2016;10(4):333-335
The zinc finger protein A20 exists in many kinds of ceils in the body and plays multiple roles in physiological and pathological processes such as regulation of immune response,inflammatory diseases and cancers by inhibiting cell apoptosis induced by tumor necrosis factor (TNF) and restricting NFKB signaling pathway.Recently,the role of A20 in generation and development of tumors draws wide attention,hence,we summarized recent research progress of the relation between A20 and cancer in this review.
2.Clinicopathologic analysis of 1018 cases of thyroid carcinoma
Jing XU ; Tingting LI ; Guang CHEN ; Wei MENG ; Guimin WANG
Chinese Journal of General Surgery 2011;26(4):279-282
Objective To explore the incidence and pathologic feature of patients with thyroid carcinoma treated at the First Hospital of Jilin University. Methods From January 2000 to July 2010,clinicopathologic data of 1018 patients with thyroid carcinoma treated in the First Hospital of Jilin University were retrospectively analyzed. Results The cases of thyroid carcinoma between 2008 and 2010 were more than 73% higher than that in the preceding 8 years. Cancer cases from January 2009 to July 2010 were more1018 cases reviewed, 976 cases were clearly classified pathologically. Papillary thyroid carcinoma, follicular thyroid carcinoma, medullary thyroid carcinoma and anaplastic thyroid carcinoma were present in 897 (91.91%), 43(4. 41% ), 22(2. 25% ) and 6(0. 61% ) cases respectively. Of the 1018 cases reviewed,804 cases were recorded with or without lymphnode metastasis. The rate of lymphnode metastasis of male and female patient were 39. 24% and 28. 64% respectively and the difference was significant( χ2 = 6. 71 ,P <0. 05). The rate of lymphnode metastasis of age <45 years and age ≥45 years were 37.65% and 23. 26%respectively and the difference was significant ( χ2 = 19. 54, P < 0. 05 ). Conclusions In the past ten and a half years, the number of the thyroid carcinoma patients treated in the First Hospital of Jilin University increased year by year. The increase of papillary thyroid carcinoma was the most obvious. Thyroid carcinoma was more common among females. The peak incidence age of males and females was 30 -59. The rate of lymphnode metastasis of males was larger than that of females. The rate of lymphnode metastasis of age <45years was larger than that of age≥45 years.
3.A case report of successful treatment of severe acute paraquat poisoning with pulmonary aspergillus infection.
Qiang CHEN ; Guang-Liang HONG ; Qiao-Meng QIU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2011;29(7):543-544
Aspergillosis
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etiology
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therapy
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Aspergillus
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Humans
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Lung Diseases, Fungal
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etiology
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therapy
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Male
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Middle Aged
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Paraquat
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poisoning
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Treatment Outcome
4.The exploration of misdiagnosis and reoperation in thyroid carcinoma
Guang CHEN ; Jiang REN ; Jia LIU ; Wei MENG ; Hongyu ZHANG ; Hui HAN ; Xianying MENG ; Qiang GUAN
Journal of Endocrine Surgery 2009;3(4):239-242
Objective To explore the reason of misdiagnosis and discuss the reoperation in thyroid carcinoma.Methods The data of 77 patients that had reoperation because of misdiagnosis were analyzed.Results The daignosis of all 77 cases were only based on pre-operative physical and uhrasound examination.The post-reoperative follow up (3~41 monthes):no case was found local recurrence.Conclusions The preoperative frozen section may avoid misdaignosis and the effect of reoperation for misdaignosed cases are satisfactory.
5.234 cases of parathyroid carcinoma
Peisong WANG ; Shuai XUE ; Shuo WANG ; Xianying MENG ; Guimin WANG ; Wei MENG ; Jia LIU ; Zhe HAN ; Guang CHEN
Chinese Journal of Endocrine Surgery 2017;11(4):334-337
6.Clinical use of AO three-dimensionally preformed titanium mesh plates for orbital fractures
Ming, CHEN ; Guang-Rui, CHAI ; Meng, WANG ; Lu, LIU ; He-Ming, LI ; He, ZHANG
International Eye Science 2015;(1):112-116
Abstract?AlM:To evaluate the accuracy and practicability of three - dimensionally preformed Arbeitsgemeinschaft Osteosynthese AO titanium mesh plates for orbital fractures.?METHODS:Forty-seven patients with isolated blow-out orbital fractures were included in this study. Fracture locations were as follows: floor/medial wall ( n = 26, 55%), medial wall ( n = 12, 26%), and floor ( n = 9, 19%) . The floor fractures were exposed by a standard transconjunctival approach, whereas a combined transcaruncular transconjunctival approach was used in patients with medial wall fractures with temporary dissection of inferior oblique muscle. A three -dimensionally preformed AO titanium mesh plate was selected according to the size of the defect previously measured on the preoperative computed tomographic scan examination and fixed at the inferior orbital rim with 2 screws. The accuracy of plate positioning of the reconstructed orbit was assessed on the postoperative computed tomography ( CT) scan. The practicability of clinical use of AO three - dimensionally preformed titanium mesh plates was assessed on the preoperative and postoperative clinical data.?RESULTS: Postoperative orbital CT scan showed an anatomic three- dimensional placement of the orbital mesh plates in all of the patients. All patients had a successful treatment outcome without clinical complications. 40 patients ( 87%) had a successful enophthalmos correction. 25 patients ( 86%) had a successful recovery from diplopia.?CONCLUSlON: Three- dimensionally preformed AO titanium mesh plates for orbital fracture reconstruction results in an accurate anatomic restoration of the bony orbital contour with a high rate of success to correctenophthalmos and diplopia.
7.Clinic analysis of phoenix roebelenii pollen's allergens sensitization in Hainan province
Chunlin LI ; Weiwei XIE ; Shuo LIU ; Guang MENG ; Qi LONG ; Qiongxiang CAI ; Jurong CHEN
Chinese Archives of Otolaryngology-Head and Neck Surgery 2015;(10):520-522
[ABSTRACT]OBJECTIVETo investigate the phoenix roebelenii pollen as the allergen of allergic rhinitis in Hainan Province and provide guidance for prevention and treatment of allergic rhinitits.METHODSA total of 2054 patients with allergic rhinitis were tested with the allergen of phoenix roebelenii pollen by skin prick test, and then choose 30 positive cases to give the nasal mucosa provocation test. RESULTSThe total positive rate of allergen of phoenix roebelenii pollen by skin prick test was 67.38% (1384/2054). The 30 cases with positive skin prick test were all positive in nasal mucosa provocation test and the cases in control group were all negative.CONCLUSIONPhoenix roebelenii pollen is an important allergen in Hainan Province. There is a correlation between skin prick test and nasal mucosa provocation test. The allergen skin prick test can provide clue for the patients to avoid the pathogenic allergens and for the specific immunotherapy.
8.Expression and significance of Th1/Th2 cytokines in ankylosing spondylitis
Junxiang WANG ; Ping WEI ; Jinghong MENG ; Xiuchan LIU ; Yanjie LIU ; Guang GU ; Haiying CHEN ; Jianli XIE
Clinical Medicine of China 2008;24(10):989-990
Objective To investigate the changes and significance of Th1/Th2 cytokines in ankylosing spondyhtis (AS).Metbotis Serum and synovial fluid levels of TNF-α,IL.17.IL-10 and IL-4 were detected by en-zyme linked immunosorbent assay(ELISA)in AS cases.Results The serun levels of TNF-α,IL-17 and IL-10 were significantly higher,while the serum level of IL-4 Was significantly lower in AS group than in normal group.The levels of TNF-α.IL-17 and IL-4 in synovial fluid were significantly higher than in serum.Conclusion Disequilibrium exists in Th1/Th2 cytokine network of AS.and there is a strong predominance of Th1.
9.Design of a wireless ambulatory blood pressure monitoring system based on ARM.
Jian-guo ZENG ; Guang-meng CHEN ; Jian WANG
Chinese Journal of Medical Instrumentation 2006;30(6):424-427
A design of the wireless ambulatory blood pressure monitoring system has been presented based on ARM embedded microprocessor and GPRS module for the extention of native mobile telemedicine. The whole system framework and flow chart have been introduced in detail. Based on RBF neural networks, the ambulatory blood pressure data curve has been simulated, and the trend curve provides a reliable gist for the prevention, treatment, diagnosis and therapeutic efficacy of cerebrocardiac diseases.
Algorithms
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Blood Pressure Monitoring, Ambulatory
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instrumentation
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Computer Communication Networks
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Equipment Design
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Humans
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Neural Networks (Computer)
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Signal Processing, Computer-Assisted
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instrumentation
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Software