1.Study on food and antioxidant intake in smokers and non-smokers in China.
Yu-Na HE ; Feng-Ying ZHAI ; Yi-Song HU ; Zhi-Hong WANG ; Xiao-Guang YANG
Chinese Journal of Epidemiology 2006;27(9):785-788
OBJECTIVETo examine the differences in food and antioxidant vitamin intake in current non-smokers,light smokers,and heavy smokers.
METHODS51 115 people (24 077 male, 27 038 female) aged above 15 years who had completed providing information on smoking habit and dietary intake, were selected from 2002 national health and nutrition survey.
RESULTSAfter adjustment for geographic areas and age, data showed the smokers ate more light vegetable and alcohol, less dark vegetable and fruit than non-smokers. Male smokers consumed more energetic stuff and macronutrients than non-smokers, but female smokers had opposite trends. Light smokers (LS) consumed less antioxidant than non-smokers (NS) after adjusted for area, age, BMI and energy, with carotene (Male LS = 1824.7 microg, NS = 1964.8 microg; Female LS = 1565.4 microg, NS = 2127.4 microg), thiamin (Male LS = 0.84 mg, NS = 0.85 mg; Female LS = 0.72 mg, NS = 0.74 mg), vitamin E (alpha) (Male LS = 9.2 mg, NS = 9.3 mg; Female LS = 7.4 mg, NS = 8.1 mg), vitamin C (Male LS = 91.2 mg, NS = 94.2 mg; Female LS = 76.9 mg, NS = 87.5 mg).
CONCLUSIONSmokers had a significantly lower overall mean dietary antioxidant vitamin intake than non-smokers. Increasing the daily consumption of variety of fruits and vegetables had been recommended to reduce the risk of chronic diseases.
Antioxidants ; administration & dosage ; Case-Control Studies ; China ; Diet ; Female ; Fruit ; Humans ; Male ; Nutritional Status ; Smoking ; Vegetables ; Vitamins ; administration & dosage
2.Treatment of epilepsy with bipolar electro-coagulation: an analysis of cortical blood flow and histological change in temporal lobe.
Zhi-Qiang CUI ; Guo-Ming LUAN ; Jian ZHOU ; Feng ZHAI ; Yu-Guang GUAN ; Min BAO
Chinese Medical Journal 2015;128(2):210-215
BACKGROUNDBipolar electro-coagulation has a reported efficacy in treating epilepsy involving functional cortex by pure electro-coagulation or combination with resection. However, the mechanisms of bipolar electro-coagulation are not completely known. We studied the acute cortical blood flow and histological changes after bipolar electro-coagulation in 24 patients with intractable temporal lobe epilepsy.
METHODSTwenty-four patients were consecutively enrolled, and divided into three groups according to the date of admission. The regional cortical blood flow (rCBF), electrocorticography, the depth of cortex damage, and acute histological changes (H and E staining, neuronal staining and neurofilament (NF) staining) were analyzed before and after the operation. The t-test analysis was used to compare the rCBF before and after the operation.
RESULTSThe rCBF after coagulation was significantly reduced (P < 0.05). The spikes were significantly reduced after electro-coagulation. For the temporal cortex, the depth of cortical damage with output power of 2-9 W after electro-coagulation was 0.34 ± 0.03, 0.48 ± 0.06, 0.69 ± 0.06, 0.84 ± 0.09, 0.98 ± 0.08, 1.10 ± 0.11, 1.11 ± 0.09, and 1.22 ± 0.11 mm, respectively. Coagulation with output power of 4-5 W completely damaged the neurons and NF protein in the molecular layer, external granular layer, and external pyramidal layer.
CONCLUSIONSThe electro-coagulation not only destroyed the neurons and NF protein, but also reduced the rCBF. We concluded that the injuries caused by electro-coagulation would prevent horizontal synchronization and spread of epileptic discharges, and partially destroy the epileptic focus.
Adult ; Electrocoagulation ; methods ; Epilepsy ; surgery ; Epilepsy, Temporal Lobe ; surgery ; Female ; Humans ; Male ; Temporal Lobe ; surgery ; Young Adult
3.Combined transperineal and transpubic urethroplasty for patients with complex male pelvic fracture urethral distraction defect.
Jian Wei WANG ; Li Bo MAN ; Xiao XU ; Zhen Hua LIU ; Feng HE ; Guang Lin HUANG ; Jian Po ZHAI ; Ning ZHOU ; Wei LI
Journal of Peking University(Health Sciences) 2020;52(4):646-650
OBJECTIVE:
To evaluate the clinical effects and characteristics of combined transperineal and transpubic urethroplasty for patients with complex pelvic fracture urethral distraction defect (PFUDD).
METHODS:
We retrospectively reviewed the clinical data of 17 male patients with complex posterior PFUDD from January 2010 to December 2019. The complications included urethrorectal fistulas in 2 patients (11.8%), urethroperineal fistula in 1 patient (5.9%). Ten patients had undergone previous treatments: dilatation in 3 patients (17.6%), internal urethrotomy in 1 patient, failed urethroplasty in 6 patients (35.3%), of whom 2 patients had two times of failed urethroplasties. All the patients were performed with urethroplasty by combined transperineal and transpubic approach with removing the entire pubic bone followed by the anastomosis.
RESULTS:
The mean age of the patients included in this study was 35.5 (range: 21-62) years. The mean length of stricture was 5.5 (range: 4.5-7.0) cm, the mean follow-up was 27 (range: 7-110) months, the mean time of operation was 190 (range: 150-260) min, the mean evaluated blood loss was 460 (range: 200-1 200) mL. There were 5 patients who needed blood transfusion intraoperatively or postoperatively. Wound infection was seen in 4 out of 17 patients and thrombosis of lower extremities in 1 out of 17 patients. The last follow-up showed that the mean postoperative maximum urinary flow rate was 22.7 (range: 15.5-40.7) mL/s. After removing the catheter, one patient presented with decreased urinary flow and symptoms of urinary infection. Cystoscopy showed the recurrent anastomotic stricture, which was cured by internal urethrotomy. In our series, the success rate of the combined transperineal and transpubic urethroplasty was 94.1% (16/17).
CONCLUSION
Combined transperineal and transpubic urtheroplasty can achieve a tension free anastomosis after removing the entire wedge of pubis in some patients with complex PFUDD. However, this procedure should be completed in a regional referral hospital due to the complexity of the operation and the high percentage of complications.
Adult
;
Anastomosis, Surgical
;
Fractures, Bone/surgery*
;
Humans
;
Male
;
Middle Aged
;
Pelvic Bones
;
Retrospective Studies
;
Treatment Outcome
;
Urethra
;
Urethral Stricture
;
Young Adult
4.Measurement of serum free light chains and its clinical significance in 20 newly diagnosed patients of multiple myeloma.
Xiao-Bei MAO ; Xie-Qun CHEN ; Yong-Ping ZHAI ; Rong LIANG ; Guang-Xun GAO ; Guo-Guang MA ; Ya-Ping YU ; Feng LI
Journal of Experimental Hematology 2008;16(4):829-832
The objective of this study was to explore the clinical significance of measuring serum free light chains (sFLC) and to compare with serum total light chains (free and binded) in multiple myeloma (MM). sFLC in 20 newly diagnosed MM patients and 20 cases of healthy people as control were measured by immuno-nephelometric assays; the serum light chains and kappa/lambda ratio were measured in all patients, while immunofixation electrophoresis (IFE) tests were carried out at the same time in 18 out of 20 patients. The results showed that the abnormality of serum free light chains and kappa/lambda ratio were found in all of the 20 newly diagnosed MM patients (p < 0.01). The measurement of sFLC showed higher sensitivity than the total serum chains (p < 0.01). It is concluded that the method testing sFLC by immuno-nephelometric assay combined with kappa/lambda ratio is valuable for MM diagnosis, and the measurement of sFLC can be used as one of indicators for MM diagnosis.
Adult
;
Aged
;
Biomarkers, Tumor
;
blood
;
Female
;
Humans
;
Immunoglobulin kappa-Chains
;
blood
;
Immunoglobulin lambda-Chains
;
blood
;
Male
;
Middle Aged
;
Multiple Myeloma
;
blood
5.The prevalence of body overweight and obesity and its changes among Chinese people during 1992 to 2002.
Guan-sheng MA ; Yan-ping LI ; Yang-feng WU ; Feng-ying ZHAI ; Zhao-hui CUI ; Xiao-qi HU ; De-chun LUAN ; Yong-hua HU ; Xiao-guang YANG
Chinese Journal of Preventive Medicine 2005;39(5):311-315
OBJECTIVETo describe the prevalence of body overweight and obesity and its changes among Chinese people during 1992-2002, and to provide scientific basis for developing intervention strategies for obesity in China.
METHODSThe data from "1992 China third National Nutrition Survey" (78,704 subjects, 38,323 male and 40,381 female) and from "2002 China National Nutrition and Health Survey" (209,849 subjects, 101,377 male and 108,472 female) were used in this study. The overweight and obesity were defined by using WHO Z-score criteria for children younger than 7 years old, Chinese age-, sex-specific BMI criteria for children aged 7-17 years, and Chinese BMI criteria for adults.
RESULTSThe overall prevalence of overweight and obesity of Chinese people was increased by 38.6% and 80.6%, respectively during the period of 1992-2002. The prevalence of overweight and obesity of Chinese people aged 0-6 years, 7-17 years, 18-44 years, 45-59 years and above 60 years was increased 31.7%, 17.9%, 66.7%, 45.2% and 43.7%, respectively. The increase of the prevalence of overweight and obesity was higher in girls younger than 6 years than their male counterparts, while among other age groups, that were higher in boys than girls. The prevalence of overweight and obesity among people living in rural areas was lower than that of their urban counterparts, while the increment of overweight and obesity prevalence among rural people was greater than that of their urban counterparts. It was estimated that another 70 million overweight and 30 million obese Chinese people emerged in China from 1992 to 2002.
CONCLUSIONThe prevalence of overweight and obesity of Chinese people was increased rapidly in the past decade, which had affected 260 million Chinese people. It would continue to increase in the near future if effective intervention measures have not been taken.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Child ; Child, Preschool ; China ; epidemiology ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Obesity ; epidemiology ; Overweight ; epidemiology ; Prevalence ; Rural Population ; statistics & numerical data ; Urban Population ; statistics & numerical data ; Young Adult
6.The relationship of milk consumption and development of 3 - 6 years old preschool children.
Jian-qiang LAI ; Shi-an YIN ; Guan-sheng MA ; Jian-hua PIAO ; Feng-ying ZHAI ; Nan LI ; Xiao-guang YANG
Chinese Journal of Preventive Medicine 2007;41(3):169-171
OBJECTIVETo study the relationship between milk intake of 3 - 6 years old preschool children and their growth.
METHODSThe data bank of 2002 China National and Health Survey were used to analyze the relationship of milk consumption and the growth of children aged 3 - 6 in urban and rural areas.
RESULTSThe percentages of the diet with milk in urban and rural areas were 46.9% and 8.2% respectively, there was significant difference between the urban and rural areas. The averaged milk intake of preschool children were 23.8 g/d, the milk intake of urban children was significantly higher than that in the rural areas (P < 0.01). The height and weight of children with milk or its products in their diets in the group aged 4, 5 and 6 years were significantly higher than those of children without milk or its products in their diets (P < 0.05).
CONCLUSIONThere was close relationship between milk intake of children 3 - 6 years old and their growth, the volume of milk intake of preschool children should be improved in urban and rural areas.
Animals ; Body Height ; Body Weight ; Child ; Child, Preschool ; China ; Dairy Products ; Diet ; Health Surveys ; Humans ; Milk ; Rural Population ; statistics & numerical data ; Urban Population ; statistics & numerical data
7.Comparison of assessment of food intakes by using 3 dietary survey methods.
Yan-ping LI ; Yu-na HE ; Feng-ying ZHAI ; Xiao-guang YANG ; Xiao-qi HU ; Wen-hua ZHAO ; Guan-sheng MA
Chinese Journal of Preventive Medicine 2006;40(4):273-280
OBJECTIVETo analyze the difference and correlation of food intakes assessed by Food Weighted Record, 24 Hours Recall and Food Frequency Questionnaire (FFQ) methods.
SUBJECTSThe data of 2002 China National Nutrition and Health Survey were used. All 23,198 subjects (male 11,107, female 12,091) finished all three dietary survey methods. Food Weighted Record method weighted all food items consumed at home by all family members in last 3 days; 24 Hours Recall recorded all food items the subjects consumed at and out home in last 3 days; FFQ recorded the main 33 categories food items that the subjects consumed at and out home in last year.
RESULTSCompared to Food Weighted Record method, food intakes assessed by 24 hours recall were similar, and the relative differences were less than 10% of most food items. The proportion of over-report and under-report (+/- 25%) by 24 Hours Recall were less than 40%. The correlation coefficients of food intakes between Food Weighted Record and 24 Hours Recall methods ranged from 0.58 to 0.88. The results from Food Weighted Record and FFQ were similar among the high frequently consumed food items. The relative differences of the food intakes investigated between Food Weighted Record and FFQ were less than 15% and the proportion of over-report and under-report (+/- 25%) by FFQ were more than 50%. The correlation coefficients of food intakes between Food Weighted Record and FFQ ranged from 0.08 to 0.76.
CONCLUSIONFood intakes might be assessed accurately by the Food Weighted Record revised 24 Hours Recall method, and FFQ method be also used to assess the food intakes, especially for the frequently consumed food items, as to studying the relationship between food consumption and health.
Data Collection ; Diet Surveys ; Eating ; Female ; Humans ; Male ; Sampling Studies
8.A description on the Chinese national nutrition and health survey in 2002.
Li-ming LI ; Ke-qin RAO ; Ling-zhi KONG ; Chong-hua YAO ; Hong-ding XIANG ; Feng-ying ZHAI ; Guan-sheng MA ; Xiao-guang YANG ; null
Chinese Journal of Epidemiology 2005;26(7):478-484
OBJECTIVETo describe the status of nutrition and health related indices in the Chinese population.
METHODSA stratified multi-stage cluster sampling was used from 31 provinces, autonomous regions, and municipalities. The survey was done in 2002, including data gathered from questionnaires, interviews, physical examinations, measurement of biochemical indices, and dietary investigation.
RESULTSCereals accounted for 48.5% of all the sources of energy in urban and 61.4% in rural populations. Daily mean percentages of calories for total fat were 35.0% in urban and 27.5% in rural areas. The prevalence rates of stunting and underweight were 14.3% and 7.8% respectively in young children under 5-year-old. The prevalence of vitamin A deficiency was 9.3% in Chinese children aged 3-12 years old. The total prevalence of anemia was 15.2% in general population of all ages. The prevalence of anemia in young adults was significantly higher in women than in men. The total prevalence rates of overweight and obesity were 17.6% and 5.6%, respectively. The prevalence rates of hypertension, diabetes, hypercholesteremia, hypertriglyceridemia, or low serum high density lipoprotein cholesterol were 18.8%, 2.6%, 2.9%, 11.9%, 7.4% respectively in Chinese adults aged 18 and over. The rates of awareness, treatment, and under control among hypertensives were 30.2%, 24.7%, and 25.0%, respectively. Significant regional and age differences were revealed in the dietary habit and the prevalence of various diseases. The prevalence of diseases associated with malnutrition were higher in rural than in urban areas. In contrast, the prevalence of conditions associated with overconsumption and inappropriate dietary patterns were higher in urban than in rural populations.
CONCLUSIONChinese people were currently suffering from both problems on nutrition related issues and burdens of diseases which were characterized in nutrient deficiencies and overconsumption, malnutrition and noncommunicable conditions associated with overconsumption and inappropriate diet. The difference of nutrition and health status between rural and urban people was also seen.
Adolescent ; Adult ; Anemia ; epidemiology ; Child ; Child, Preschool ; China ; Chronic Disease ; epidemiology ; Diabetes Mellitus ; epidemiology ; Diet ; statistics & numerical data ; Eating ; Energy Intake ; Female ; Growth and Development ; Health Surveys ; Humans ; Hypertension ; epidemiology ; Infant ; Lipids ; blood ; Male ; Middle Aged ; Nutrition Surveys ; Obesity ; epidemiology ; Pregnancy ; Vitamin A Deficiency ; epidemiology ; Young Adult
9.Disease risks of childhood obesity in China.
Yan-Ping LI ; Xiao-Guang YANG ; Feng-Ying ZHAI ; Jian-Hua PIAO ; Wen-Hua ZHAO ; Jian ZHANG ; Guan-Sheng MA
Biomedical and Environmental Sciences 2005;18(6):401-410
OBJECTIVETo estimate the relative risks of dyslipidemia, hypertension, diabetes mellitus, and metabolic syndromes among overweight and obese Chinese children compared with their normal weight counterparts.
METHODSOverweight and obesity were defined by age- and sex-specific BMI classification reference for Chinese children and adolescents. Pediatric metabolic syndrome (MetS) and each risk factor for MetS were defined using the criteria for US adolescents. Definition of hyper-TC, LDL, and dyslipidemia for adults was applied as well. General linear model factor analysis and chi-square test were used to compare the difference in metabolic indicators among normal weight, overweight, and obese groups. Multiple logistic regression analysis was performed to estimate the odds ratio of metabolic abnormalities between obesity, overweight, and normal weight children, after adjustment for living area, family economic level, age, sex, and daily exercise time and TV watching time, as well as different dietary indices in the model.
RESULTSSignificant increases in blood lipids, glucose, and blood pressure were found among overweight and obese children as compared with their counterparts with normal weight. By applying WGOC-recommended BMI classification, the risks for hypertriglyceridemia, low HDL and dyslipidemia among overweight children were 1.9, 1.4, and 1.5 times, and was 3.3, 1.5, and 1.8 times among obese groups compared to their counterparts with normal weight after adjustment for age, sex, region, socioeconomic status, physical activity, and dietary intakes. The overweight and obese children (15-17.9 years) had a high-risk of developing hypertension, which was 2.3 and 2.9 times higher than their counterparts with normal weight. Above 90% obese adolescents had abdominal obesity, while less than 1% normal weight ones had abdominal obesity. No obese adolescents were free from any risk factors for MetS, while 36.9% of normal weight adolescents were from the risk factors. 83.3% obese boys and all obese girls had metabolic syndrome, while only 15.5% normal weight boys and 18.8% normal weight girls had metabolic syndrome. Four risk factors for metabolic syndrome were found in 8.3% obese boys while none in normal weight boys and girls. The prevalence of MetS among normal weight, overweight, and obesity groups was 1.5%, 18.3%, and 38.1% respectively.
CONCLUSIONThe cardiovascular disease (CVD) risk factors are clustered in obese Chinese children. Our observations strongly suggest that efforts should be made to prevent the onset of overweight and its associated diseases during early childhood.
Adolescent ; Child ; China ; epidemiology ; Diabetes Mellitus ; epidemiology ; Dyslipidemias ; epidemiology ; etiology ; Female ; Humans ; Hypertension ; epidemiology ; etiology ; Male ; Obesity ; complications ; epidemiology ; Risk Factors
10.Analysis of the levels of serum total calcium and inorganic phosphate of 2,342 children in Beijing.
Cheng-li XU ; Sheng-kai YAN ; Shu-yu ZU ; Ying SHEN ; Feng-ying ZHAI ; Shao-mei HAN ; Li-wei ZHANG ; Guang-jin ZHU
Acta Academiae Medicinae Sinicae 2004;26(4):455-459
OBJECTIVETo study the changes of serum total calcium (Ca) and inorganic phosphate (P) levels during children growth and related factors.
METHODSUsing a stratified-multi-steps-cluster sampling method, we selected 2,342 healthy children aged 10-18 years from urban and suburban areas of Beijing from September 2001 to December 2001 to test the levels of serum Ca and P. Their meal status was also surveyed to analyse the correlation of the leves of serum Ca and P with sex, age, height, weight, and diet on statistic basis.
RESULTSThe Ca levels of Beijing children were (2.39 +/- 0.12) mmol/L, which had a positive correlation with age, height, and weight (P < 0.01). The Ca levels of female children were somewhat higher than those of male [male, (2.38 +/- 0.12) mmol/L; female, (2.39 +/- 0.12) mmol/L; P < 0.05]. The Ca levels of urban children were significantly higher than those of suburban children [urban, (2.40 +/- 0.13) mmol/L; suburban, (2.37 +/- 0.10) mmol/L; P < 0.001]. The P levels of Beijing children were (1.39 +/- 0.18) mmol/L, which had a negative correlation with age, height, and weight (P < 0.01). The P levels of male children were significantly higher than those of female [male, (1.43 +/- 0.18) mmol/L; female, (1.36 +/- 0.17) mmol/L; P < 0.001]. The P levels of urban children were significant higher than those of suburban children [urban, (1.41 +/- 0.19) mmol/L; suburban, (1.38 +/- 0.16) mmol/L; P < 0.001]. The Ca levels of Beijing children had a negative correlation with P levels (r=-0.141, P < 0.01). [Ca] x [P] (mmol/L) of Beijing children were 3.32 +/- 0.44. The value of [Ca] x [P] reached peak by 3.45 +/- 0.46 when Beijing children were of 13-14 years old, and then the value declined with increasing age.
CONCLUSIONThe levels of serum Ca and P correlates with sex, age, growth, and diet. The level of serum Ca goes up while P goes down during the children growth.
Adolescent ; Age Factors ; Body Height ; Body Mass Index ; Body Weight ; Calcium ; blood ; Child ; Child Development ; Female ; Humans ; Male ; Phosphorus ; blood ; Reference Values ; Sampling Studies ; Sex Factors ; Urban Health