1.Anatomical study on compression of tibial nerve and it's branches in ankle and foot
Guang YU ; Zhigang LIU ; Quan LIN
Journal of Jilin University(Medicine Edition) 2006;0(05):-
Objective To observe the branches and distribution of the tibial nerve and analyze the compressed position of it.Methods Twenty sides of adult cadavers were anatomized and the tibial nerve branches in ankle,foot,the internal and external plantar tunnel were observed.Correlated data was measured and recorded.Results ① The tendinous part of abductor hallucis muscle that was located under the muscle and consisted the surface of the internal and external plantar tunnel was(8.62?0.79)cm in length,(3.01?0.30)cm in width,and the thickness of it was about(0.24?0.02)cm.The internal and external nerves were located in the internal and external tunnel.The length of the internal tunnel was about(4.58?0.41)cm,and the diameter was(1.11?0.10)cm.The length of the external tunnel was about(2.58?0.23)cm,the diameter was about(0.96?0.08)cm.② Internal hell nerve was in an isolated tunnel interior the hell,which was the hell tunnel.The length of the hell tunnel was about(3.03?0.21)cm,the diameter was(1.07?0.09)cm.Conclusion The tibial nerve branches can be compressed at internal,external plantar tunnel or the heel tunnel.When making neurolysis of the tibial nerve for tarsal tunnel syndrome patients,except for the flexor retinaculum,the internal and external plantar tunnel and the hell tunnel should also be decompressed especially for the patients with the symptom of compressed single branch.
7.APPLICATION OF CELL ENZYME IMMUNOASSAY FOR DETECTION AND ANALYSIS OF MONOCLONAL ANTIBODIES TO HUMAN COLORECTAL ADENOCARCINOMA
Jun WANG ; Caixia LIN ; Hui YU ; Guang LI
Chinese Journal of Immunology 1985;0(02):-
A solid-phase cell enzyme-linked immunoassay is described for screeningand analyzing monoclonal antibodies against the cell surface antigensof human colorectal adenocarcinoma.Horse-radish peroxidase conjugatedProtein A was used to detect the binding of mouse monoclonal antibodiesto human colorectal adenocarcinoma.HR_(8348) cells which had been cultured inand then fixed to the wells of microtiter plates by using glutaraldehyde.Thismethod was found to be specific,reproducible and practical,and especiallyto be advantageous for the large scale screening and analyzing of monoclo-nal antibodies with a panel of cell types.
8.Adaptive Reaction of Actin Cytoskeleton in Podocyte Structure of Glomerulus
yu-lin, KANG ; guang-hua, ZHU ; wei-xun, HE
Journal of Applied Clinical Pediatrics 1992;0(05):-
Actin cytoskeleton in podocyte is a complicated network structure,and the stability of this structure depend on many proteins which located in slit diaphragm,the apical membrane domain and the basal membrane domain with the stimulus of mechanical stress,the actin cytoskeleton can be adaptive regulated to maintain the normal function of glomerulus,and several signal pathways involve in the process,such as RhoA/Rho kinase signal pathway and TRPC6.
9.Effects of curcumin on apoptosis and caspase-3 expression in cortex tissue in rats with hypoxic ischemic brain damage.
Guang-Mei YIN ; Lin-Sheng YU ; Shu-Zhen WU ; Guang-Hua YE
Chinese Journal of Applied Physiology 2010;26(4):504-506
Animals
;
Apoptosis
;
drug effects
;
Brain
;
drug effects
;
Caspase 3
;
metabolism
;
Curcumin
;
pharmacology
;
Hypoxia-Ischemia, Brain
;
metabolism
;
pathology
;
Male
;
Rats
;
Rats, Sprague-Dawley
10.Therapeutic Effects of Low-Dose Topiramate on Children with Tourette Syndrome
guang-yu, LIN ; li-min, LIN ; yu-sheng, LIN ; yi, WU ; pai-zhen, CHEN ; wan-li, ZHUANG ; lian, MA
Journal of Applied Clinical Pediatrics 2004;0(12):-
Objective To explore the therapeutic effects and dose of Topiramate(TPM)in children with Tourette syndrome(TS).Me-thods Seventy-nine children with TS were given oral TPM,which were treated with Topiramate [0.5-3.0 mg/(kg?d),twice a day].The therapeutic effects were assessed using Yale Global Tic Severity Scale(YGTSS)before and 3 months after treatment and the side-effects of the drugs were observed.Results The differences of YGTSS scores before and after treatment,motertic score(19.63?3.09 vs 5.05?1.74),vocaltic score[(18.95?2.56)vs(4.82?1.94)],global scole score[(24.21?5.89)vs(10.42?3.69)],severity score[(62.21?5.81)vs(22.26?4.81)],there were significant differences of every score of YGTSS between before and after treatment(Pa