1.Diagnosis and treatment of pediatric allergic rhinitis with comorbid diseases except asthma and upper airway cough syndrome.
Ze-Zhang TAO ; Rong-Guang WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2011;46(1):23-25
Asthma
;
Child
;
Cough
;
Humans
;
Rhinitis, Allergic, Perennial
;
complications
;
diagnosis
;
therapy
2.Fifty-six cases of Hunt facial paralysis treated by syndrome differentiation acupuncture combined with buccal mucosal bleeding.
Yi YANG ; Guang-Tao ZHOU ; De-Qing ZHANG
Chinese Acupuncture & Moxibustion 2012;32(2):111-112
Acupuncture Therapy
;
Adolescent
;
Adult
;
Aged
;
Bloodletting
;
Combined Modality Therapy
;
Facial Paralysis
;
therapy
;
Female
;
Humans
;
Male
;
Middle Aged
;
Mouth Mucosa
;
blood supply
;
Young Adult
3.Effects of adriamycin on cultured mouse podocytes VEGF expressions and the potential protective effects of dexamethasone.
Xiao-zhong LI ; Hai-tao YUAN ; Xue-guang ZHANG
Chinese Journal of Pediatrics 2003;41(2):146-146
Animals
;
Antibiotics, Antineoplastic
;
pharmacology
;
Blotting, Northern
;
Cells, Cultured
;
Dexamethasone
;
pharmacology
;
Doxorubicin
;
pharmacology
;
Enzyme-Linked Immunosorbent Assay
;
Gene Expression Regulation
;
drug effects
;
Glucocorticoids
;
pharmacology
;
Kidney Glomerulus
;
cytology
;
drug effects
;
metabolism
;
Mice
;
RNA, Messenger
;
drug effects
;
genetics
;
metabolism
;
Vascular Endothelial Growth Factor A
;
genetics
;
metabolism
4.Advance in the Research of Axonal Damage Mechanism in Multiple Sclerosis (review)
Jin-tao ZHANG ; Guang-yu XING ; Ling YIN
Chinese Journal of Rehabilitation Theory and Practice 2006;12(10):885-887
To review the advance in research of axonal damage mechanism of multiple sclerosis (MS) in recent years. To explain the evidence and effect of morphology and imageology in axonal damage of MS. And, to show the progression in the mechanism of axonal damage in MS.
5.Re-discrimination on "reinforcement can be achieved by slow-yet-rapid needling, and rapid-yet-slow needling weakens evil qi".
Chen-guang ZHANG ; Guang-zheng TAO ; Heng-hui XIE
Chinese Acupuncture & Moxibustion 2007;27(5):387-390
OBJECTIVETo study on the original meanings of "reinforcement can be achieved by slow-yet-rapid needling, and rapid-yet-slow needling weakens evil-qi", one of important bases of reinforcing-reducing in acupuncture.
METHODSUsing the principle of knowledge archaeology and through structure an d through structure analysis on the subjects described by "slow" and "rapid" and the papers appearing the words, the meanings of this sentence are re-discriminated.
CONCLUSION"Slow-rapid" prescribed in the reinforcing-reducing needling method in Huangdi's Internal Classic includes 3 subjects: pulse condition, needle-retained time, and velocity of withdrawing the needle. The "slow-rapid" in "reinforcement can be achieved by slow-yet-rapid needling, and rapid-yet-slow needling weakens evil-qi" should be pulse condition, but was not needling method, which means that the pulse changes from slow to rapid, marked by transformation of channels from deficiency to excess; the transform of the pulse from rapid to slow means that the channel transforms from excess to deficiency.
Acupuncture Therapy ; Humans ; Medicine, Chinese Traditional
6.Ultrasound-guided minimally invasive biopsy techniques in thyroid surgery
Guang ZHANG ; Xuehai BIAN ; Tao ZHAO ; Chunhai ZHANG ; Yantao FU ; Hui SUN
International Journal of Surgery 2010;37(2):79-81
Objective To approach the guide of ultrasound-guided minimally invasive biopsy technique in diagnosis and treatment of thyroid diseases. Methods One hundred and seventeen cases (a total of 131 nodules, nodules 0. 5-1.5 cm in diameter, with an average diameter of approximately 0. 8 cm) with thyroid nodules , under Ultrasound-guided minimally invasive biopsy techniques from October 2008 to July 2009 were analyzed. Result One hundred and seventeen cases of patients with biopsy derived satisfaction were not ap-parent discomfort and complications after biopsy. Across 59 cases of surgical treatment in patients with biop-sy, and preoperative biopsy and postoperative pathologic is not fully consistent in only two cases, 58 patients without surgical treatment, who is combined with symptoms, palpation, serum thyroxine and color Doppler ultrasound and other laboratory examinations, and regularly review treated with symptomatic treatment, the symptoms, and color Doppler ultrasound imaging were much better under the treatment. 8 cases of patients in 117 cases of minimally invasive biopsy have cervical lymph node biopsy at the same time, biopsy patholo-gy and postoperative results are consistent with postoperative pathologic (7 cases of metastatic carcinoma, 1 case of reactive hyperplasia), accuracy was 100%. Conclusion Uhrasound-guided minimally invasive bi-opsy technique have important guiding for diagnosis and treatment of thyroid diseases, consistent with the high rate of clinical, especially for the preoperative diagnosis of small nodules, to avoid unnecessary over-treatment, can also reduce the misdiagnosis of thyroid cancer. While this technology is simple, safe and ac-curate, which have clinical value in the thyroid surgery.
8.Effects of activation and inhibition of Stat 3 signaling pathway on invasion of human pancreatic cancer cells
Guang YANG ; Zhengjun QIU ; Fang ZHANG ; Tao JIANG ; Kejian HUANG ; Jun CAO ; Chen HUANG
Tumor 2009;(7):645-649
Objective: In order to investigate the effects of activating and blocking Stat3 signaling pathway on invasion ability of human pancreatic cancer cells and explore its action mechanism.Methods:Human pancreatic cancer Capan-2 cells were treated with IL-6. SW1990 human pancreatic cancer cells were treated with AG490. Cell proliferation was measured by MTT assay. Western blotting and immunocytochemistry were performed to detect expression of phosphorylated Stat3 (p-Stat3) protein. Real-time fluorogentic quantitative PCR (RFQ-PCR) and Western blotting were used to detect the mRNA and protein expression of VEGF and MMP-2 mRNA, respectively. The invasion abilities of SW1990 and Capan-2 cells were determined by cell invasion assay in vitro. Results:IL-6 stimulated the proliferation of Capan-2 cells (P<0.05), elevated the expression of p-Stat3, increased the mRNA and protein expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 2 (MMP-2) (P<0.05), and enhanced the invasion ability of Capan-2 cells. AG490 inhibited the proliferation of SW1990 cells (P<0.05), down-regulated the expression of p-Stat3, markedly decreased the mRNA and protein expression of VEGF and MMP-2 (P<0.05), and weakened the invasion ability of SW1990 cells. Conclusion:Stat 3 signaling pathway plays an important role in the invasion and metastasis of pancreatic cancer. Stat 3 signaling transduction pathway may provide a novel therapeutic target for the treatment of pancreatic cancer.
9.Comparative study on the effects of different therapeutic methods in preventing and treating nonalcoholic fatty liver in rats.
Tao LIU ; Lili YANG ; Li ZHANG ; Haiyan SONG ; Dongfei LI ; Guang JI
Journal of Integrative Medicine 2012;10(10):1120-6
To explore the pathogenesis of nonalcoholic fatty liver (NAFL) in traditional Chinese medicine (TCM) by comparing the therapeutic efficacy of methods for fortifying the spleen and replenishing qi, warming yang and fortifying the spleen and warming yang to move water.
10.Danshensu inhibits acetaldehyde-induced proliferation and activation of hepatic stellate cell-T6.
Li ZHANG ; Tao WU ; Junming CHEN ; Lili YANG ; Haiyan SONG ; Guang JI
Journal of Integrative Medicine 2012;10(10):1155-61
To evaluate the effects of danshensu, the main component of the extract of Chinese medicine Salvia miltiorrhiza, on the proliferation and activation of hepatic stellate cells (HSCs).