1.Anomalous systemic arterial supply to normal basal segments of the left lower lobe of the lung:characteristic findings on chest radiography and spiral CT
Guang-Zhao YANG ; Shun-Biao ZHAO ; Ming CHAO ;
Chinese Journal of Radiology 2001;0(08):-
Objective To summarize the characteristic findings on chest radiography and spiral CT of anomalous systemic arterial supply to normal basal segments of the left lower lobe of the lung.Methods Five patients with anomalous systemic arterial supply to normal basal segments of the left lower lobe of the lung were retrospectively reviewed.Chest radiography,and contrast-enhanced spiral CT scan were analyzed. Results On posteroanterior chest radiographs,the findings in 5 cases of this anomaly were all shown as a retrocardiac mass,narrowing lower lobar pulmonary artery shadow,and without normal lower lobar pulmonary artery branches but there were dilated abnormal markings in left lower lung zone.On contrast- enhanced spiral CT scans,the involved left lower lobe of the lung had mild volume loss but normal bronchial trees in all 5 cases and areas of ground-glass opacity in 2 cases.The absence of normal left lower lobar pulmonary artery distal to the origin of superior segmental artery,anomalous systemic artery originating from the descending aorta,diffuse dilatation of the systemic arterial branches distributed in the basal segments of the left lower lobe were also found in all the patients.One patient who underwent angiography had similar vessel features with spiral CT.Conclusion There are some characteristic findings on chest radiography in this anomaly.the contrast-enhanced spiral CT scans are important in diagnosing and avoiding invasive angiography and life-threatening lung biopsy.
2.Analysis of clinical effects of iliolumbar fixation in treating sacrum fracture of Denis type II.
Zhe-biao CAO ; Zhao-ming YE ; Yong-jin ZHANG ; Zhao-guang MAO ; Fu-gen ZHOU
China Journal of Orthopaedics and Traumatology 2016;29(3):248-251
OBJECTIVETo evaluate the clinical effects of iliolumbar fixation for the sacrum fractures of Denis type II.
METHODSThe clinical data of 86 patients with sacrum fracture of Denis type II treated by iliolumbar fixation from January 2008 to January 2012 were retrospectively analyzed. There were 55 males and 31 females, aged from 17 to 55 years old with an average of 39.1 years. Among them, 73 cases complicated with pelvis fracture and 13 cases with acetabular fracture; 37 cases with sacral neurological symptoms and 49 cases without sacral neurological symptoms. Fracture healing time, nerve function, clinical function and complications were observed in the patients.
RESULTSIn 86 cases, 6 cases were out of followed-up and 80 cases were followed up from 24 to 71 months with an average of 36 months. The mean fracture healing time was 13 weeks (ranged, 10 to 38 weeks). According to Gibbons scoring to evaluate the neurological function, preoperative nerve rehabilitation, lower limbs feeling, lower limbs activity,bladder and rectum function,total score respectively were 0.62 +/- 0.04, 1.54 +/- 0.35, 1.12 +/- 0.18, 0.23 +/- 0.01, 3.46 +/- 0.47 and postoperative respectively were 0.82 +/- 0.12, 0.36 +/- 0.04, 0.05 +/- 0.01, 0.03 +/- 0.01, 1.25 +/- 0.22, there were statistically significant differences between preoperative and postoperative (P < 0.05). According to Majeed scoring to evaluate the clinical function, postoperative pain, standing, sitting, sexual life, work ability, total score respectively were 22.54 +/- 4.02, 27.93 +/- 5.46, 8.47 +/- 3.61, 2.54 +/- 1.33, 16.46 +/- 4.34, 81.32 +/- 8.73, 60 cases got excellent results, 17 good, 3 fair. The main complications including fracture nonunion of 5 cases,deep incision infection of 1 case, and screw prominence resulting uncomfortable of 8 cases.
CONCLUSIONIliolumbar fixation has the advantages of stable fixation, satisfactory functional rehabilitation, less complications, and is a good method in treating sacrum fracture of Denis type II.
Adolescent ; Adult ; Bone Screws ; Female ; Fracture Fixation, Internal ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sacrum ; injuries ; surgery ; Spinal Fractures ; surgery ; Treatment Outcome ; Young Adult
3.Effects on osteoblast and adipocyte differentiation of bone marrow mesenchymal stimulated by pulsed electromagnetic fields
Yong YANG ; Hua WU ; Dong-Ming ZHAO ; Wen-Chun ZHAO ; Run-Guang LI ;
Chinese Journal of Physical Medicine and Rehabilitation 2003;0(08):-
Objective To study the effects of pulsed electromagnetic fields(PEMFs)of 15Hz and lmT on osteoblast differentiation of bone marrow mesenchymal stem cells.Methods The bone marrow mesenchymal stem cells were isolated and cultured in vitro,the third passage cells were harvested and half of them was exposed to PEMFs,another half exposed to sham PEMFs served as the control.The activity of ALP was measured.And the ex- pression of osteoblast and adipogenesis was measured with the semi-quantitative RT-PCR,adipogenic differentiation was observed with the Oil Red O Staining.Results When compared with the control,PEMFs of 15 Hz and 1 mT significantly increased the activity of ALP(P
4.Differentiation Between Vaccine Strain and Field Isolates of Classical Swine Fever Virus Using Polymerase Chain Reaction and Restriction Test
Yun ZHAO ; Yu-Ming QIN ; Guang-Chuan ZHANG ; Qi-Zu ZHAO ; Yi-Bao NIN ;
Microbiology 1992;0(03):-
A nest RT-PCR/restriction test has been developed in order to distinguish the lapinised vaccine strain from field isolates of classical swine fever virus. The restriction enzyme cut sites mapping of the major coding sequence of E2 gene lapinised vaccine strain and ShiMen strain of classical swine fever virus have been compared. Ten and sixteen unique restriction markers have been found in the lapinised vaccine strain and ShiMen strain. The restriction enzyme cut sites mapping of the twenty six unique restriction marker in the major coding sequence of E2 gene of 17 classical swine fever field isolates have been analyzed. Only 3 sites (HgaI、Hin8I及Hsp92I) are present in the lapinised vaccine strain sequence. Two pans of nested primers and a criteria of analysis have been designed for HgaI restriction marker site. The tests have been conducted first on the lapinised vaccine strain and ShiMen strain of classical swine fever virus resulting in predicted restrection patterns. Finally, the tests have been applied to 5 field isolates of different gene group analyzed by phylogenetic study. The result showed that only HCLV strain gene can be cut to 2 fragment by Hgal , and ShiMen strain and 5 field isolates cant be cut At the same time the sensitivity and specificity of nest RT-PCR have been tested. The sensitivity is 0. 2MLD. The specific fragment of BDV and BVDV were not obtained by the nest RT-PCR. These results showed that the development of the nest RT-PCR/restriction tests is very important for the control and perish of classical swine fever in china.
5.Efficacy of combined pranoprofen eye drops and artificial tears on the treatment of mild to moderate dry eye syndrome after trabbeculectomy
Guang-Ming, ZHAO ; Ping, ZHAO ; Bao-Ling, NI ; Zhong-Gang, YI ; Cheng, YANG ; Jing-Jing, ZHENG
International Eye Science 2015;(2):370-372
AlM:To evaluate the efficacy of combined pranoprofen eye drops and artificial tears on the treatment of mild to moderate dry eye syndrome after trabbeculectomy.METHODS:This prospective case control study included 63 cases (63 eyes) of patients with mild to moderate dry eye syndrome after trabbeculectomy in our hospital from November 2013 to June 2013. All subjects were randomly divided into two groups. Observation group was treated with combined pranoprofen eye drops and artificial tears and control group received simple artificial tears marking the eyes at 1, 2, 4wk. The patient's symptoms, signs, BUT, S▏t, and FL were observed before treatment and 1, 2, 4wk after treatment.RESULTS: After 2wk, the symptoms of observation group were improved, there was statistically significant difference (P<0. 05). FL difference of each group was statistically significant ( P<0. 05 ); After 4wk, symptoms and signs were improved. There was statistically significant difference ( P < 0. 05 ). The BUT of the observation group and corneal FL scores of two groups showed significant differences (P<0. 05). CONCLUSlON: Artificial tears joint pranoprofen eye drops has good curative effect in the treatment of mild to moderate dry eye syndrome after trabbeculectomy.
8.RESEARCH ON THE TESTING OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS BY NESTRT-PCR
Yun ZHAO ; Guang-Chuan ZHANG ; Yu-Ming QIN ; Yi-Bao NING ; Qin WANG ;
Microbiology 1992;0(06):-
Three primer were designed based on the consevered area of the genetic of the ATCC VR-2332 strain and LV strain. And the nest RT-PCR of testing porcine reproductive and respiratory syndrome virus were developed. The nest RT-PCR against ATCC VR-2332 strain, LV strain and B13 strain were done by this method.The DNA fragment were obtained specially from the three strains isolated from different region. The size were 430bp (430bp) , 410bp (413bp) and 410 bp (413bp) separately. But the DNA fragment were not obtained from HCV, PPV and PRV. Its sensitivity was 10-2 TCID50. It's sensitivity increased 10000 times than one step RT-PCR. It should make the method of testing porcine reproductive and respiratory syndrome virus more sensitive, fast and accurate.
9.Pharmacokinetics and relative bioavailability of tramadol hydrochloride tabletin Chinese healthy volunteers
Bo CHEN ; Zhao-Hong ZENG ; Guo-Guang MAO ; Yue-Ming MA ; Qiu ZHONG ;
Chinese Journal of Clinical Pharmacology and Therapeutics 1999;0(04):-
0. 05). Conclu-sion The THT and THC have bioequivalence.
10. Research progress on the pathogenesis and treatment of sepsis-induced liver injury
Medical Journal of Chinese People's Liberation Army 2019;44(6):515-520
Liver injury induced by sepsis is one manifestation of sepsis-induced multiple organ dysfunction syndrome, which often indicates the severity of illness with poor prognosis. In recent years, more and more studies have shown that liver microcirculatory dysfunction, energy metabolism dysfunction, oxidative stress, inflammatory response, apoptosis or necrosis of hepatocyte and other mechanisms play an extremely important role in the development of sepsis - induced liver injury. Fully understand the mechanism of occurrence and development of sepsis - induced liver injury, which will help to prevent and control better, and reduce the incidence and mortality effectively. Therefore, this article reviews the current research progress about the pathogenesis and treatment measures of sepsis - induced liver injury.