2.Biological characteristics of porous tantalum:short-term application is clinically safe but the long-term effect needs to be further studied
Bin LI ; Yongxin HUA ; Guang YANG
Chinese Journal of Tissue Engineering Research 2014;(43):7028-7032
BACKGROUND:Porous tantalum, characterized as high porosity, low elastic modulus, high friction coefficient, stable biological properties, good compatibility and typical structural properties, has been the focus in medicine, especial y in orthopedics. <br> OBJECTIVE:To review the biological characteristics of porous tantalum, including its mechanical properties, compatibility, and biological activity. <br> METHODS:A computer-based search of PubMed, CSTJ, Wanfang and VIP databases was done for articles relevant to porous tantalum published from 1990 to 2014 using the keywords of“porous tantalum, biological character, orthopedic applications”both in English and Chinese. <br> RESULTS AND CONCLUSION:Porous tantalum, with high porosity, low elastic modulus, high friction coefficient, and good compatibility, has become increasingly popular in medicine, especial y in orthopedics. At present, porous tantalum is used in the preparation of the integrated acetabular cup, total hip arthroplasty acetabular cup, acetabular reinforcing pad, porous tantalum metal rod, tibial plateau prosthesis and patel ar prosthesis and tibial plateau prosthesis. The short-term fol ow-up of porous tantalum implants in orthopedic surgery has been reported. And clinical data, radiology, histological analysis of the removed material have proved the practicability and safety of the porous tantalum. But the long-term effects of porous tantalum remain to be confirmed.
3.The effect of fluoride toxicity on free radical level in rats
Xing-hua, LI ; Bo, SUN ; Guang-sheng, LI
Chinese Journal of Endemiology 2001;20(2):98-99
Objective Recently,it was reported the analy sis of bone free radical by using electron spin resonance (ESR),so this article aimed to determine the changes of bone free radical in fluoresis rats.Methods To analyze the free radical level of bone in fluoresis rats fed with different dose of calcium by ESR method.Results The free radical of bone in the group of low ca lcium level and the group low calcium+fluorides was higher than that in the cont rol group (P<0.01),but that in normal animal feeds (calcium-rich)+fluoride group was lower than that in the control group.Conclusions Low doses of fluoride did not resulted in the increase of free radical in calcium-rich condition at short time,but at low calcium condition,fluoride could increase the level of free radical,these suggested that simple overdose of fluoride did not change the level of free radical of bone.
5.Headles cannulated screw for the treatment of Freiberg disease.
Chang-hua LI ; Guang-mao LIN ; Wei-liang WANG
China Journal of Orthopaedics and Traumatology 2013;26(12):1057-1058
Bone Screws
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utilization
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Female
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Foot Diseases
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surgery
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Fracture Fixation, Internal
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instrumentation
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methods
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Humans
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Internal Fixators
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utilization
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Metatarsus
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abnormalities
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surgery
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Osteochondritis
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congenital
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surgery
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Young Adult
7.Porous tantalum in orthopedic applications:joint replacement and cartilage reconstruction scaffolds
Bin LI ; Qing XIA ; Yongxin HUA ; Guang YANG ; Xiaojie PEI
Chinese Journal of Tissue Engineering Research 2015;(12):1943-1947
BACKGROUND:Porous tantalum with high porosity, low elastic modulus, high friction coefficient has stable biological characters and good biocompatibility, which is considered as an ideal implant material in orthopedic surgery. OBJECTIVE:To review the application situation of porous tantalum used in artificial joints, spine, bone necrosis, defects of bone and so on. METHODS:A computer-based search of PubMed, Wanfang, and VIP databases was performed for relevant articles published from 1990 to 2014 using the keywords of “porous tantalum, biological character, orthopedic applications” in English and Chinese. RESULTS AND CONCLUSION:Porous tantalum is a kind of good orthopedic implant material, with high porosity, low elastic modulus, high friction coefficient, and good compatibility. Porous tantalum is mostly used in the preparation of integrated acetabular cup, total hip arthroplasty acetabular cup, acetabular reinforcing pad, porous tantalum metal rod, tibial plateau prosthesis, patelar prosthesis and tibial plateau prosthesis, which has achieved good clinical effects.
8.Characteristics of Attentional Blink in Patients with Depression
Ning LI ; Yin-hua WANG ; Xu-guang GAO
Chinese Journal of Rehabilitation Theory and Practice 2006;12(6):511-512
ObjectiveTo investigate the characteristics of attentional blink (AB) in the patients with depression.MethodsThirty-five antidepressant-free, non-elderly patients with depression diagnosed according to CCMD-Ⅲ as well as thirty-five health control subjects matched for education, age and sex were tested with the rapid serial visual presentation (RSVP) paradigm.ResultsAll cases of two groups showed an AB, and AB for depressive participants was larger and longer.ConclusionThe patients with depression have attentional impairments.
9.Reaction Time in Patients with Depression
Yin-hua WANG ; Ning LI ; Xu-guang GAO
Chinese Journal of Rehabilitation Theory and Practice 2006;12(11):983-986
ObjectiveTo investigate whether subjects with major depression display attention deficits.Methods35 antidepressant-free,non-elderly patients with unipolar depression diagnosis according to ICD-10 and CCMD-Ⅲ as well as 35 health control subjects matched for education,age and sex were administered three tests for attention(sustained attention,Selective attention and Attention Blink).ResultsOn the Continuous Performance Test(CPT),depressed participants needed more reaction time and made more mistake than nondepressed participants.There were no differences between two block in reaction time in the CPT of patients and control subjects.The performance on the Stroop Color-Word Test was impaired in depression.Compared with normal subjects,depressed participants presented increased choice reaction times(CRT).Stroop interference was higher in depressed patients than in controls.On Attention Blink(AB) paradigm,both groups performed equally well at reporting the first target appearing in a rapidly presented stream of stimuli.All groups showed an AB,and AB for depressive participants were larger and longer.Correlations were observed between the HAMD score and the reaction time in CPT.ConclusionThe depressive participants showed a decrement tendency in vigilance,a higher Stroop interference and a larger and longer AB.
10.The study of expression of matrix metaUoproteinases-2 in patients with colorectal cancer
Ya MA ; Guang-Ling CAI ; Guang-Yin YU ; Wei-Hua YIN ; Li CHEN ;
Chinese Journal of Primary Medicine and Pharmacy 2005;0(11):-
Objective Research the correlation between expression of MMP-2 in colorectal cancer and patho- logical factors,or biological behaviors in colorectal cancer.Methods The expression of MMP-2 in 68 cases with col- orectal cancer were detected by immunohistochemical staining.Results The expression of MMP-2 in colorectal can- cer was not correlated with tumor region and histologic type,but related with depth of tumor invasion and metasta- sis.The frequency of positive cases in patients with colorectal cancer with of lymph,node metastasis was significantly higher than that in patients without lymph node metastasis(P