1.Metabolic syndrome: cunent status and perspective.
Chinese Journal of Epidemiology 2006;27(12):1018-1019
2.Experts comment.
Chinese Journal of Pediatrics 2011;49(11):813-813
5.Effect of nicotine on coagulation abnormalities in endotoxemic rats
Wei LIU ; Jianguo LI ; Xuemin SONG ; Hui HANG ; Guang LI
Chinese Journal of Anesthesiology 2011;31(3):338-341
Objective To investigate the effect of nicotine on coagulation abnormalities in endotoxemic rats.Methods Ninety-six male SD rats weighing 200-250 g were randomly divided into 4 groups (n=24 each): group normal saline (group NS);group LPS;group nicotine(group NIC)and group α-bungarotoxin (α7 nicotinic acetylcholine receptor antagonist, group α-BGT) . Endotoxemia was induced by LPS 10 mg/kg injected via femoral vein in LPS, NIC and α-BGT groups. In group NIC nicotine 400 μg/kg was injected intraperitoneally at 30 min before LPS injection. In group α-BGT α-BGT 1 μg/kg was injected intraperitoneally at 15 min before intraperitoneal nicotine. Prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(Fib),antithrombin (AT),von Willebrand factor(vWF),plasminogen activator inhibitor-1(PAI-1),D-dimer,platelet count and TNF-α were measured before (baseline) and 2, 4 and 6 h after LPS injection.Results PT and APTT were significantly prolonged and plasma Fib and AT concentrations and platelet count were significantly decreased, while plasma PAI-1, D-dimer, vWF and TNF-α concentrations were significantly increased after LPS administration in group LPS as compared with group NS. Nitotine pretreatment significantly attenuated the LPS-induced changes in group NIC.The effect of nicotine was counteracted by α-BGT. Conclusion Nicotine can attenuate coagulation abnormalities induced by LPS by acting on α7 nicotinic acetylcholine receptor.
6.Epithelioid angiosarcoma after radical mastectomy for breast carcinoma: a case report.
Hong-ji DING ; Guo-guang WEI ; Li-qun YU ; Qi-song WU ; Yan-guang DONG
Chinese Journal of Pathology 2006;35(10):637-638
Aged
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Antigens, CD34
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metabolism
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Breast Neoplasms
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metabolism
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pathology
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therapy
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Chemotherapy, Adjuvant
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Combined Modality Therapy
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Epithelioid Cells
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pathology
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Female
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Follow-Up Studies
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Hemangiosarcoma
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metabolism
;
pathology
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Humans
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Immunohistochemistry
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Mastectomy, Radical
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Neoplasms, Second Primary
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metabolism
;
pathology
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Radiotherapy, Adjuvant
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Vimentin
;
metabolism
7.The study of expression of matrix metaUoproteinases-2 in patients with colorectal cancer
Ya MA ; Guang-Ling CAI ; Guang-Yin YU ; Wei-Hua YIN ; Li CHEN ;
Chinese Journal of Primary Medicine and Pharmacy 2005;0(11):-
Objective Research the correlation between expression of MMP-2 in colorectal cancer and patho- logical factors,or biological behaviors in colorectal cancer.Methods The expression of MMP-2 in 68 cases with col- orectal cancer were detected by immunohistochemical staining.Results The expression of MMP-2 in colorectal can- cer was not correlated with tumor region and histologic type,but related with depth of tumor invasion and metasta- sis.The frequency of positive cases in patients with colorectal cancer with of lymph,node metastasis was significantly higher than that in patients without lymph node metastasis(P
8.Newly onset non-Hodgkin's lymphomas presenting as WAIHA: a clinical and laboratory analysis of 6 cases.
Bo-ting WU ; Feng LI ; Wei-guang WANG
Chinese Journal of Hematology 2012;33(1):64-65
Anemia, Hemolytic, Autoimmune
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complications
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immunology
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pathology
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Antibodies
;
immunology
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Female
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Humans
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Lymphoma, Non-Hodgkin
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etiology
;
immunology
;
pathology
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Male
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Middle Aged
9.Headles cannulated screw for the treatment of Freiberg disease.
Chang-hua LI ; Guang-mao LIN ; Wei-liang WANG
China Journal of Orthopaedics and Traumatology 2013;26(12):1057-1058
Bone Screws
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utilization
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Female
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Foot Diseases
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surgery
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Fracture Fixation, Internal
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instrumentation
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methods
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Humans
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Internal Fixators
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utilization
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Metatarsus
;
abnormalities
;
surgery
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Osteochondritis
;
congenital
;
surgery
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Young Adult
10.Effect of intravitreal bevacizumab injection before vitrectomy on proliferative diabetic retinopathy
Cai-Rui, LI ; Shu-Guang, SUN ; Wei, HONG
International Eye Science 2010;10(9):1654-1656
AIM: To evaluate the effect of intravitreal bevacizumab (IVB) injection 1 week before pars plana vitrectomy (PPV) in proliferative diabetic retinopathy (PDR) patients. METHODS: A retrospective research was done on 46 PDR patients who were divided into PPV group (n=28) and IVB group (n=18, PPV with preoperative IVB). Bevacizumab was injected 1 week before PPV. Main outcome measures were visual acuity, incidence of iatrogenic retinal breaks, intraoperative and postoperative bleeding. RESULTS: At 1 month after surgery, visual acuity in PPV (82.1%) and IVB group (88.9%) improved significantly (P<0.01) and the difference between the two groups was not significant. Iatrogenic retinal breaks were reported in 18 cases (64.3%) in PPV group and 4 cases (22.2%) in IVB group (P<0.05). Intraoperative bleeding was encountered in all cases in PPV group and 7 cases (39%) in IVB group (P<0.01). Postoperative bleeding was reported in 9 cases (32.1%) in PPV group and none in IVB group (P<0.01). CONCLUSION: IVB injection before PPV is helpful in reducing iatrogenic retinal breaks, intraoperative and postoperative bleeding in PDR patients.