Bone Diseases ; chemically induced ; epidemiology ; China ; epidemiology ; Chronic Disease ; Fluoride Poisoning ; epidemiology ; etiology ; genetics ; Fluorosis, Dental ; epidemiology ; etiology ; Humans ; Prevalence

Objective: To study the effect of rosiglitazone on the bone microarchitecture of bilaterally ovariectomized(OVX) rats. Methods: Twenty-one 24-week-old skeletally mature rats were bilaterally ovariectomized, and were randomly divided into three groups (n = 7) : Control group(C group) ,Rosiglitazone A group(RA group) ,and Rosiglitazone B group (RB group). Rats in RA group were given i. g 0. 35 mg/d rosiglitazone for four weeks and those in the RB group were given i. g 0. 70 mg/d rosiglitazone. Rats in the control group were given normal saline in the same manner. The rats were sacrificed four weeks later. The bone volume/tissue volume (BV/T V) , the trabecular number(Tb. N), the trabecular thickness ( Tb. Th), the trabecular separation Th. Sp), and the bone surface/bone volume (BS/BV) of the femur, tibia, and lumbar were determined by micro-computered tomography(micro-CT). Results: Compared with the control group, the Tb. N,Tb. Th, and BS/BV of the femur, tibia, and lumbar all decreased significantly in RA group (except for the BS/BV of tibia) (P<0. 05, P<0. 01) ; the Tb. SP of tibia and lumbar in the RA group were significantly increased (P<0. 05) ; and there were no differences in BV/TV between the two groups. Compared with control group, the Tb, N, Tb. Th, and BS/BV of the femur, tibia, and lumbar were decreased significantly in RB group (P<0. 05, P<0. 01); the Tb. Sp of tibia and lumbar increased significantly (P<0. 05); and the BV/TV had no differences between the two groups. There were no significant differences between the RA group and RB group concerning all the parameters. Conclusion: Rosiglitazone can cause injury to the bone microarchitecture, especially to the cancellous part of the bone.

Acupuncture Points ; Acupuncture Therapy ; methods ; Adult ; Aged ; Female ; Humans ; Injections ; Male ; Middle Aged ; Sleep Apnea, Obstructive ; therapy

Air Pollutants ; analysis ; Animals ; Child ; Esters ; toxicity ; Humans ; Liver ; drug effects ; Phthalic Acids ; analysis ; metabolism ; toxicity ; Reproduction ; drug effects ; Soil Pollutants ; analysis ; Thyroid Gland ; drug effects ; Water Pollutants, Chemical ; analysis

Adolescent ; Adult ; Arrhythmias, Cardiac ; therapy ; Chiropractic ; Combined Modality Therapy ; Humans ; Male ; Massage ; Middle Aged ; Young Adult

Relevant literatures on the relationship betw een fluorosis and oxidative stress were reviewed.Based on most of the original papers published in recent years,we can see the increased free radicals and oxidative stress may occur in certain stage of fluoride intoxication,but confirmation of the causality between oxidative stress and fluoride-induced damages still remains much work to do.

The fresh conidia powder of Beauveria bassiana SGBB8702 produced with diphasic technology was dried using 36-h procedures of vacuum-freeze drying (VFD) or vacuum drying (VD). The VFD and VD procedures reduced water content of the fresh conidia powder from 58.56% to 3.97% and 4.26%, resulting in preparations containing 1.29, and 1.25?10 11 conidia/g. The VFD or VD conidia had the same viability (≥98%) as the fresh ones but germinated slightly more slowly than the fresh ones. The estimates of LC 50 s for the fresh, VFD, and VD conidia against Myzus persicae on day 7 after inoculation were 1.15, 5.89, and 2.95?10 4 conidia/ml, respectively. At the concentration of 10 6 conidia/ml, the LT 50 of the fresh conidia against M. persicae was estimated as 3.6 d, corresponding to 3.9 d and 4.4 d for the VFD and VD conidia, respectively. Due to much lower cost, the VD procedure was of greater potential for drying B. bassiana conidia in mass production though the VFD procedures resulted in slightly better quality of conidia powder. The viability and virulence of the VFD conidia were assessed periodically during 12-mon storage at 4℃ and 20℃, respectively. No viable conidia stored at 20℃ were detected 255 d after storage whereas those stored at 4℃ had a viability of 90.15% and an LT 50 of 4.7 d at the end of 12-mon storage. The results showed that storage of B. bassiana conidia powder at ambient temperature was unable to maintain shelf life at commercially acceptable level even though its water content was reduced to

Adolescent ; Adult ; Capsules ; Drugs, Chinese Herbal ; therapeutic use ; Hepatitis B, Chronic ; drug therapy ; Humans ; Male ; Middle Aged ; Phytotherapy

Bone Density ; physiology ; Bone Diseases ; epidemiology ; etiology ; metabolism ; pathology ; Calcium ; metabolism ; China ; epidemiology ; Endemic Diseases ; Fluoride Poisoning ; epidemiology ; etiology ; metabolism ; pathology ; Humans ; Osteoblasts ; physiology ; Oxidative Stress ; Parathyroid Hormone ; metabolism ; Thioredoxins ; metabolism ; Transcription Factor AP-1 ; metabolism