1.Approaches to construct the faculty's professionalism in medical schools
Basic & Clinical Medicine 2006;0(03):-
Professional development of faculty is an essential component of strategy for medical schools to construct teaching team.Development of education is dependent upon the professional quality of teaching staff.Starting from connotation of faculty's professionalism,this paper compared present status of composition of teaching staff in China with that in foreign countries,explored the potential approaches for medical schools to strengthen the construction and sustainable development of teaching staff.
2.Chinese Medicine Master Lin Qianliang
Jiaqi GUAN ; Qianliangtutor LIN
Journal of Zhejiang Chinese Medical University 2016;40(2):114-116
Objective]To appreciate Professor Lin's rigorous attitude of research,discuss and analyze his research findings in Traditional Chinese Pharmacy, academic thinking and achievements. [Methods]We put in order his academic papers,articles,as well as the materials science books of half a century, followed Professor Lin's visiting and studying across the country,summed up and gave comparative analysis as well as referring to detailed quotation and abstract.[Results]Professor Lin,about the spirit of learning,concentrated on the research thoroughly,made his academic achievement gradually and improved himself step by step.He had extensive interest and wide reading,committed to inheritance and improvement.His academic thinking reflected the value of history,respected tradition and followed the code and had comprehensive and innovative advantages.In his professional field,he also showed a wonderful career ethics such as caring for the people, simple prescription, attention to compatibility of Chinese Medicinal Herbs and thought highly of the classics. His academic achievements included textbooks and monographs, medical history and the history of medicine,herbal cuisine and tea treatment, as well as studies of both prescriptions and pharmacies since ancient times till now.All his achievements involved culture both at home and abroad. [Conclusion] Professor Lin Qianliang was born of poor parentage, but he concentrated on studies. He has excellent academic attitude and rich academic achievements,a wide rang of knowledge,which is worth learning and passing on to the younger generations.
3.Clinical Observation of Acupuncture plus Hyperbaric Oxygen for Post-stroke Depression
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):508-510
Objective To observe the therapeutic efficacy of acupuncture plus hyperbaric oxygen in treating post-stroke depression. Method Sixty patients with post-stroke depression were randomized into a treatment group of 30 cases and a control group of 30 cases. The treatment group was intervened by acupuncture plus hyperbaric oxygen, while the control group was by Fluoxetine. Before and after intervention, the Hamilton Depression scale (HAMD) was adopted for evaluation, and the efficacies were compared. Result The total effective rate of the treatment group was significantly higher than that of the control (P<0.01);after intervention, the HAMD score of the treatment group was markedly lower than that of the control (P<0.01). Conclusion Acupuncture plus hyperbaric oxygen can obviously improve the depression symptom and promote the recovery of neurologic function in patients with post-stroke depression.
4.Implication of androgen receptor gene methylation in transformation of hormone-resistance in prostate carcinoma
Chinese Journal of Urology 2006;0(S1):-
Objective To study the mechanisms underlying this loss of AR expression in rat prostate cancer. Methods The methylation status of the AR gene promoter region in rat prostate cancer and cell lines (PLS10,20,and 30) was investigated by Southern blotting,methylation-specific polymerase chain reaction,and methylation-sensitive single-strand conformation analysis (MS-SSQA). Results AR mRNA expression was not detected in any of the rat prostate cancers or cancer cell lines tested by Northern blot analysis. Higher levels of methylated CpGs were observed in PLS20 than that in PLS10 or 30. Demethylation treatment by 5-aza-2’-deoxycytidine restored AR mRNA expression in PLS20.The CpGs was suggested to be responsible for AR expression in rat prostate cancer,and found to be located-9 and-1 nucleotides upstream of the transcriptional initiation site.All of the examined rat prostate and seminal vesicle cancers demonstrated hypermethylation at these CpG sites. Conclusions These data clearly demonstrate that aberrant hypermethylation in the AR promoter region may play a critical role in AR expression in rat prostate cancers.Loss of AR expression might result in development of hormone-resistant prostate carcinoma.
5.Establishment of transplantable rat prostate carcinomas and study of its relationship to hormone dependency
Chinese Journal of Urology 2006;0(S2):-
Objective To establish transplantable rat prostate carcinoma and study its relationship to hormone dependency. Methods Six transplantable rat prostate carcinoma lines were established from primary tumors developing in the dorsolateral prostate of F344 rats receiving a combined treatment with 3, 2’-dimethyl-4-aminobiphenyl (DMAB) and testosterone propionate (TP). Results Growth in the subcutis of nude mice (ICR-nu/nu) is rapid with a doubling time of approximately 10 days and transplantability is 100%. The histological appearance of the transplanted tumors is very similar to that of the primaries and their structures have not been altered by after 8 passages. Androgen receptor immunohistochemistry revealed all to be negative. Conclusions These data indicate that the model should prove useful for studies of invasion, metastasis, and hormone dependency of prostate carcinomas.
6.Antibiotic resistance of Neisseria gonorrhoeae isolates from female patients
Chinese Journal of Infection and Chemotherapy 2006;0(04):-
Objective To investigate antibiotic resistance of Neisseria gonorrhoeae strains isolated from female patients. Methods:Antimicrobial susceptibility of N.gonorrhoeae to 7 antibiotics was tested by disk diffusion method and penicillinase- producing N.gonorrhea(PPNG)was confirmed by nitrocefin disk.Results:Of the 95 strains collected,38(40%)were found to be PPNG.No resistance to spectinomycin was identified.The susceptibility rate of these isolates to penicillin,tetracycline, and ciprofloxacin were much lower,only from 0% to 2.6%.More than 90% of the isolates were susceptible to cefuroxime, ceftriaxone,and ceftizoxime.Conclusions:Our study suggests that spectinomycin,cefuroxime,ceftriaxone,ceftizoxime are the first choice for treatment of gonorrhea in female patients.
7.Differentiation of xanthomonads causing the bacterial leaf spot of poinsettia in China from the pathotype strain of Xanthomonas axonopodis pv. poinsettiicola.
Bin LI ; Guan-lin XIE ; J SWINGS
Journal of Zhejiang University. Science. B 2005;6(6):451-453
In October 2003, a new bacterial disease with symptoms similar to those caused by Xanthomonas axonopodis pv. poinsettiicola was observed on poinsettia leaves at a flower nursery in Zhejiang Province of China. Three Xanthomonas strains were isolated from infected plants and classified as X. axonopodis. They were differentiated from the pathotype strain LMG849 of X. axonopodis pv. poinsettiicola causing bacterial leaf spot of poinsettia by comparison of pathogenicity, substrate utilization and BOX-PCR genomic fingerprints.
Cell Differentiation
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China
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Euphorbia
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microbiology
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Plant Diseases
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microbiology
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Plant Leaves
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microbiology
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Species Specificity
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Xanthomonas
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classification
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genetics
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isolation & purification
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pathogenicity
8.Perioperative nursing of patients with primary venous reflux disease of lower extremity
Yumei GUAN ; Yihua YANG ; Qiong LIN
Chinese Journal of Practical Nursing 2008;24(21):20-21
Objective To discuss the perioperative nursing experience of patients with primary venous reflux disease(PVRD)of lower extremity undergoing external valvuloplasty of superficial femoral vein.Methods Patients(146 cases)with PVRD of lower extremity were given psychological nursing,observation of postoperative complications and rehabilitation exercise instruction.Results Five limbs appeared short lymphatic seepage and other limbs recovered completely.No thrombus Was seen.Venous claudication,swelling and pain disappeared in 90.4% patients.Limbs symptom alleviated in 9.6% patients.All varicos evein disappeared.The function of deep vein valve recovered in 92% patients by color doppler ultra sonoscope re-examination.Conclusions General evaluation before operation,good perioperative psycho logical nursing and attention to the complication and rehabilitation exercise instruction are significant for reduction of postoperative complication and improvement of success rate of operation.
9.Study on Cold-soak Extraction of Fat-soluble Components in Radix Salviae Miltiorrhizae
Zhongze LIN ; Donghui LIU ; Shixia GUAN
Journal of Guangzhou University of Traditional Chinese Medicine 2000;0(04):-
Objective To explore the optimal process conditions for cold-soaking extraction of fat-soluble components in Radix Salviae Miltiorrhizae.Methods Tanshione Ⅱwas determined by HPLC.The effect of different concentrations of ethanol and comminution on the extraction rate of tanshione Ⅱwas observed,and the process conditions were optimized by orthogonal test.Results The optimal process conditions for obtaining higher extraction rate of tanshione Ⅱwere as follows: the medicinal material was extracted by cold-soak extraction with 95% ethanol for two times(3 hours for each time),and the volume of ethanol was as much as 8 times of the medicinal material.Conclusion The extraction process is simple,stable and efficient for Radix Salviae Miltiorrhizae.
10.Clinical Observation on Huangqi Injection in Inhibiting the Side Effects Induced by Chemotherapy
Meiying LIN ; Ying GUAN ; Encun HOU
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
[Objective] To observe the regulatory effect of Huangqi Injection (HI) on immune function of patients after chemotherapy (CT). [Methods] Thirty-four patients confirmed as acute myelogenous leukemia (AML) received two cycles of CT. During the 1st cycle, the patients were only treated with DA (daunomycin + arabinoside) regimen; in the 2nd cycle, intravenous injection of 20 mL of HI, qd for 2 weeks was added. The effect of CT on myelosuppression and immune function of the patients was observed. [Results] Immunosuppressive manifestations such as myelosuppression, fatigue, spontaneous sweating, impaired appetite, lassitude were found after the 1st cycle of CT, and peripheral immunoglobulin A (IgA), IgG, IgM and complements C3 levels were also decreased (P