No abstract available.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Ovary*

No abstract available.
Female ; Granulosa Cell Tumor ; Granulosa Cells

Granulosa cell tumors of the ovary are rare, and account for 2 to 3% of ovarian tumors. Granulosa cell tumors are discovered often in perimenopausal or postmenopausal women but 10 to 26% are found in the reproductive age group. The tumors associated with pregnancy are infrequent. In this study, we present a case of granulosa cell tumor of left ovary at pregnancy.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Ovary ; Pregnancy*

No abstract available.
Female ; Granulosa Cell Tumor ; Granulosa Cells ; Neoplasm Metastasis ; Ovary

No abstract available.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Infant*

No abstract available.
Female ; Granulosa Cells* ; Interferon-alpha* ; Rodentia*

Granulosa cell tumors are uncommon neoplasm of ovary that are characterized by their long natural history and for their tendency to recur years after an aparrent clinical cure. Endometrial cancer occurs in association with these tumor in at least 5% of cases and 25%-50% are associated with endometrial hyperplasia. In this study, we present a case of granulosa cell tumor of right ovary with endometrial cancer after left oophrectomy.
Endometrial Hyperplasia ; Endometrial Neoplasms* ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Natural History ; Ovary*

Unilocular cystic granulosa cell tumors (UCG) are extremely rare. Due to the relatively small mass of the tumor available for histologic examination, diagnosis of UCG is not easy. Here we present a case of UCG in a 54-year old female. A 12x10 cm unilocular cystic mass was identified in the right ovary. The tumor was thin-walled and consisted of a single large cavity with a smooth internal surface. In most areas there were no cells lining the cyst, however, in focal areas the unilocular cyst was lined by one or more layers of uniform granulosa cells, forming Call-Exner bodies. A diagnosis of UCG was made after multiple sections were examined. A careful histologic examination is required for the correct diagnosis of UCG.
Diagnosis ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Middle Aged ; Ovary

OBJECTIVE: The aim of this study was to describe the unique transvaginal sonographic(TVS) findings and clinical manifestations attributes of adult ovarian granulosa cell tumor(GCT) in postmenopausal women. METHODS: Data for 7 postmenopausal women with pathological proven adult ovarian GCT were respectively reviewed in Samsung Cheil Women's Hospital, between 1996 and 1999. Characteristics of transvaginal sonographic findings, pathological findings and clinical manifestations were analyzed. RESULT: On the basis of TVS findings, 7 cases of adult ovarian GCT were varied, but grossly categorized into 2 morphologic patterns: semisolid mass with scattered cystic components (n=3), muliticystic mass resembling typical hemorrhagic cyst (n=4). There are characteristics of TVS imaging of GCT that various size and stage of hemorrhage presents in the tumor. Endometrial transvaginal sonographic findings were normal atrophic EM (n=1), less than 5 mm with fluid collection (n=1), more than 5 mm with or without abnormal echogenicity (n=5). Clinical manifestations were, combination or alone, abnormal uterine bleeding (n=all), abdominal pain (n=1), mass palpation(n=3). Histopathologically most tumors were mixed, such as microfollicular, marcofollicular, trabecular pattern and also varied histologic appearance and tumor cell arrangement. CONCLUSION: TVS findings and combined presenting symptoms in postmenopausal women that raise suspicion of adult ovarian GCT include a relatively large ovarian mass (especially with hemorrhage) with a complex consistency, thickened endometrium and abnormal uterine bleeding without horomone replacement therapy. So it is possible to differentiate on basis of TVS imaging and symptoms between GCT and epithelial tumors of the ovary in postmenopausal women.
Abdominal Pain ; Adult ; Endometrium ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Hemorrhage ; Humans ; Ovary* ; Ultrasonography ; Uterine Hemorrhage

Ovarian granulosa cell tumor is a uncommon low-grade feminizing malignancy. Its natural history shows slow growth without pain. It often reveals to be very large sized mass when diagnosed, and is confined to the involved ovary in many cases. Complete surgical removal is primary treatment and recurrences thereafter are relatively common. Postoperative adjuvant therapy including reoperation, chemotherapy, radiation therapy or a combination therapy has been used with various degrees of success. We experienced a case of huge ovarian granulosa cell tumor occupying whole abdominal cavity by rapid growth, which is presented with a brief review of corresponding literatures.
Abdominal Cavity ; Drug Therapy ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Natural History ; Ovary* ; Recurrence ; Reoperation