No abstract available.
Female ; Granulosa Cell Tumor ; Granulosa Cells

No abstract available.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Ovary*

No abstract available.
Female ; Granulosa Cell Tumor ; Granulosa Cells ; Neoplasm Metastasis ; Ovary

Granulosa cell tumors of the ovary are rare, and account for 2 to 3% of ovarian tumors. Granulosa cell tumors are discovered often in perimenopausal or postmenopausal women but 10 to 26% are found in the reproductive age group. The tumors associated with pregnancy are infrequent. In this study, we present a case of granulosa cell tumor of left ovary at pregnancy.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Ovary ; Pregnancy*

No abstract available.
Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Infant*

No abstract available.
Female ; Granulosa Cells* ; Interferon-alpha* ; Rodentia*

Ovarian granulosa cell tumors are uncommon low-grade malignancies. They are characterized by their long history and their tendency to recur years after an apparent clinical cure. Only a small percentage of granulosa cell tumors metastasize, and they rarely do so to the liver. In this paper, we present a case of hepatic metastasis treated by surgery and BEP combination chemotherapy, with a brief review of corresponding literatures.
Drug Therapy, Combination ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Liver ; Neoplasm Metastasis* ; Ovary*

A 7-years-old female patient was first seen in our out-patient clinic on June 21, 1975 with five day history of progressive proptosis of the left eye. Biopsy was taken from the orbit and the submandibular lymphnodes. Exploratory laparotomy revealed ovarian malignancy. Pathologic examination confirmed generalization of ovarian granulosa-theca cell tumor.
Biopsy ; Exophthalmos ; Female ; Generalization (Psychology) ; Granulosa Cell Tumor* ; Granulosa Cells* ; Humans ; Laparotomy ; Neoplasm Metastasis* ; Orbit* ; Outpatients

Testicular granulosa cell tumor(GCT) is a rare neoplasm. We report here on an incidentally discovered testicular granulosa cell tumor in a 36-year-old man. The serum tumor markers were within the normal limits. The ultrasonographic findings revealed a mass with a heterogenous hypoechoic echotexture, including multiple variable sized cystic components. The histology on the orchiectomy specimen demonstrated a gonadal stromal tumor with granulosa cell features. Testicular granulosa cell tumor of the adult type is a very rare tumor, and there have been several isolated case reports and small serial studies described in the literature.
Adult ; Female ; Gonads ; Granulosa Cell Tumor ; Granulosa Cells ; Humans ; Orchiectomy ; Testicular Neoplasms ; Testis ; Biomarkers, Tumor

OBJECTIVE: The aim of this study was to describe the unique transvaginal sonographic(TVS) findings and clinical manifestations attributes of adult ovarian granulosa cell tumor(GCT) in postmenopausal women. METHODS: Data for 7 postmenopausal women with pathological proven adult ovarian GCT were respectively reviewed in Samsung Cheil Women's Hospital, between 1996 and 1999. Characteristics of transvaginal sonographic findings, pathological findings and clinical manifestations were analyzed. RESULT: On the basis of TVS findings, 7 cases of adult ovarian GCT were varied, but grossly categorized into 2 morphologic patterns: semisolid mass with scattered cystic components (n=3), muliticystic mass resembling typical hemorrhagic cyst (n=4). There are characteristics of TVS imaging of GCT that various size and stage of hemorrhage presents in the tumor. Endometrial transvaginal sonographic findings were normal atrophic EM (n=1), less than 5 mm with fluid collection (n=1), more than 5 mm with or without abnormal echogenicity (n=5). Clinical manifestations were, combination or alone, abnormal uterine bleeding (n=all), abdominal pain (n=1), mass palpation(n=3). Histopathologically most tumors were mixed, such as microfollicular, marcofollicular, trabecular pattern and also varied histologic appearance and tumor cell arrangement. CONCLUSION: TVS findings and combined presenting symptoms in postmenopausal women that raise suspicion of adult ovarian GCT include a relatively large ovarian mass (especially with hemorrhage) with a complex consistency, thickened endometrium and abnormal uterine bleeding without horomone replacement therapy. So it is possible to differentiate on basis of TVS imaging and symptoms between GCT and epithelial tumors of the ovary in postmenopausal women.
Abdominal Pain ; Adult ; Endometrium ; Female ; Granulosa Cell Tumor* ; Granulosa Cells* ; Hemorrhage ; Humans ; Ovary* ; Ultrasonography ; Uterine Hemorrhage