The inflammatory pseudotumor of the urinary bladder is rare, especially in children. It is a benign proliferative lesion of the submucosal stroma easily mistaken for a sarcoma clinically, so it should be differentiated from a malignant neoplasm. We report the case of bladder inflammatory pseudotumor in a 7-year-old girl.
Bladder Diseases/pathology ; Bladder Diseases/diagnosis* ; Bladder Neoplasms/diagnosis ; Case Report ; Child ; Diagnosis, Differential ; Female ; Granuloma, Plasma Cell/pathology ; Granuloma, Plasma Cell/diagnosis* ; Human ; Urography

Humans ; Dendritic Cell Sarcoma, Follicular/diagnosis* ; Granuloma, Plasma Cell/diagnosis* ; Biopsy, Needle ; Gastrointestinal Neoplasms ; Hepatitis

Plasma cell granuloma (PCG) of the lung is a rare disease that usually presents as a pulmonary nodule or mass on incidental radiographic examination without symptoms. Although the etiology of PCG is still controversial, many findings have lent support to the lesion being a reactive inflammatory process rather than a neoplastic one. We describe a 53-yr-old male who presented with a hemoptysis and have a lung mass at the left upper lobe on chest radiograph. The lung mass was primarily diagnosed as PCG by percutaneous needle aspiration and biopsy, and the patient was treated with oral steroid because he and relatives refused the operation. However, the size of the lung mass did not change and open thoracotomy and lobectomy were done therefore. He was confirmed as having pulmonary actinomycosis with PCG after surgery. To our knowledge, this is the first report of PCG associated with actinomycosis in Korea.
Middle Aged ; Male ; Lung Diseases/*complications/*diagnosis ; Humans ; Granuloma, Plasma Cell/*complications/*diagnosis ; Actinomycosis/*complications/*diagnosis

Carcinoma ; diagnosis ; Granuloma, Plasma Cell ; diagnosis ; Humans ; Laryngeal Neoplasms ; diagnosis ; Larynx ; pathology

Inflammatory pseudotumor (IPT) is an uncommon benign neoplasm of unknown etiology presenting as an incidental mass, fever, malaise, anemia, and weight loss. Generally, IPT in the lung is asymptomatic. A case of pulmonary IPT presenting as prolonged fever in a 59 year old man is presented with clinicopathological findings. The patient had been febrile for three months before admission. Five months before admission, a chest X-ray showed a small left pulmonary mass which was regarded as old tuberculosis. An chest X-ray taken on admission revealed a left pulmonary mass two times the size of the one on the first x-ray. Percutaneous needle aspiration and biopsy were performed, and the microscopic examination revealed a plasma cell reaction with myofibroblastic proliferation, consistent with IPT. As prolonged unexplained fever is a frequent symptom in patients with IPTs, this disease entity should be included in the differential diagnosis of fever of unknown origin.
Anemia ; Biopsy ; Diagnosis, Differential ; Fever of Unknown Origin* ; Fever* ; Granuloma, Plasma Cell ; Humans ; Lung ; Middle Aged ; Myofibroblasts ; Needles ; Plasma Cell Granuloma, Pulmonary* ; Plasma Cells ; Thorax ; Tuberculosis ; Weight Loss

Inflammatory pseudotumor (IPT) is an uncommon benign neoplasm of unknown etiology presenting as an incidental mass, fever, malaise, anemia, and weight loss. Generally, IPT in the lung is asymptomatic. A case of pulmonary IPT presenting as prolonged fever in a 59 year old man is presented with clinicopathological findings. The patient had been febrile for three months before admission. Five months before admission, a chest X-ray showed a small left pulmonary mass which was regarded as old tuberculosis. An chest X-ray taken on admission revealed a left pulmonary mass two times the size of the one on the first x-ray. Percutaneous needle aspiration and biopsy were performed, and the microscopic examination revealed a plasma cell reaction with myofibroblastic proliferation, consistent with IPT. As prolonged unexplained fever is a frequent symptom in patients with IPTs, this disease entity should be included in the differential diagnosis of fever of unknown origin.
Anemia ; Biopsy ; Diagnosis, Differential ; Fever of Unknown Origin* ; Fever* ; Granuloma, Plasma Cell ; Humans ; Lung ; Middle Aged ; Myofibroblasts ; Needles ; Plasma Cell Granuloma, Pulmonary* ; Plasma Cells ; Thorax ; Tuberculosis ; Weight Loss

Plasma cell Granuloma (PCG) is a form of idiopathic inflammatory pseudotumor (IPT). It is a rare entity character-ized by a nonneoplastic proliferation of inflammatory cells dominated by a polyclonal expansion of the plasma cells. This lesion has been discovered in many parts of the body including the central nervous system. We now report two cases of plasma cell granuloma involving the brain. The first case was a 42-year-old man who presented a right hemi-paresis. He had a lesion in the convexity of the left parietal region. The second case was a 58-year-old woman who was expressed confusion and a frontal-temporal headache. She had a lesion in the convexity of the left temporal region and mastoid bone. The diagnosis of PCG was confirmed by pathological and immunohistochemical studies revealing pre-dominant plasma cells in the affected tissues.
Adult ; Brain ; Central Nervous System ; Diagnosis ; Female ; Granuloma, Plasma Cell* ; Headache ; Humans ; Mastoid ; Middle Aged ; Plasma Cells* ; Plasma* ; Rabeprazole

Diagnosis, Differential ; Endoscopy ; Granuloma, Plasma Cell/diagnosis* ; Humans ; Orbital Pseudotumor ; Skull Base

Inflammatory myofibroblastic tumor is a rare tumor of mesenchymal origin. A case of intratracheal inflammatory myofibroblastic tumor in a male child was reported. The clinical characteristics, diagnosis, treatment and prognosis of the disease were reviewed based on the literature, and a differential diagnosis between inflammatory myofibroblastic tumor and hamartoma was performed to ultimately confirm the nature of the tumor in the child.
Humans ; Child ; Male ; Trachea/pathology* ; Granuloma, Plasma Cell/diagnosis* ; Prognosis ; Diagnosis, Differential ; Tomography, X-Ray Computed

Focal inflammatory lesions are benign lesions of various etiology reported in numerous anatomic sites. Because of the development of imaging study, most of focal inflammatory lesions were noted incidentally without symptom and sign. Among them, eosinophilic liver disease and inflammatory pseudotumor are relatively important diseases and are associated with a variety of other disease such as parasitic infestations, bacterial and viral infection, allergic conditions, autoimmune disease, and internal malignancies. These are largely self-limiting entities and have favorable prognosis. The terminology of eosinophilic liver disease is not strictly defined and a variety of terms, including focal eosinophilic infiltration, eosinophilic abscess, and eosinophilic granuloma exist histologically. Inflammatory pseudotumor was composed of diffuse infiltration of spindle-shaped cells, myofibroblasts, and mixed inflammatory cells (plasma cells, lymphocytes, and histiocytes), microscopically. Focal inflammatory lesions are difficult to differentiate clinically from malignant tumors, because these show variable imaging findings. Thus, it is important to preoperatively distinguish these lesions from malignancy. Meticulous liver biopsy is frequently needed to make differential diagnosis from malignant tumors and to avoid unnecessary resection.
Abscess ; Autoimmune Diseases ; Biopsy ; Diagnosis, Differential ; Eosinophilic Granuloma ; Eosinophils ; Granuloma, Plasma Cell ; Liver ; Liver Diseases ; Lymphocytes ; Myofibroblasts ; Prognosis