No abstract available.
Graft Survival* ; Kidney* ; Transplants*

No abstract available.
Graft Survival* ; Kidney* ; Transplants*

No abstract available.
Graft Survival* ; Transplants*

No abstract available.
Allografts* ; Cyclosporine* ; Graft Survival* ; Transplants*

No abstract available.
Allografts* ; Cyclosporine* ; Graft Survival* ; Transplants*

No abstract available.
Cyclosporine* ; Graft Survival* ; Kidney* ; Transplants*

No abstract available.
Allografts* ; Graft Survival* ; Humans ; Transplants*

PURPOSE: To conform the effectiveness of Cyclosporin(CsA) in penetrating keratoplasty(PKP), we compared the survival rate of grafts between CsA-used group and CsA-unused group(control group) in high risk patients. MATERIAL AND METHOD: High risk cornea was defined as vascularization in 3 or 4 quadrants, recurrent graft or corneal surface disease. We reviewed the 74 eyes(74 patients) which received penetrating keratoplasty with high risk cornea, and compared the survival rate between CsA-used group and control group. RESULT: Twenty-nine of the 74 patients were treated with CsA(17 patients with topical CsA and 12 with oral CsA ). The survival rate of CsA-used group was not superior to that of control group. CONCLUSION: CsA seems not to be effective in graft survival of high risk PKP.
Cornea ; Cyclosporine* ; Graft Survival ; Humans ; Keratoplasty, Penetrating* ; Survival Rate ; Transplants

Non-vascularized free composite graft is one of the simple and effective reconstructive options, but its clinical use has been limited due to questionable survival rate. Early vascularization is essential for graft survival and is mainly carried out via recipient bed or repaired sites. This study was designed to investigate the effect of the lateral marginal approximations on the survival of the free composite flap using a model of skin-subcutaneous composite graft in rats. Thirty 1.5 x 1.5 cm2 sized square shape composite flaps were elevated freely and reposed in place immediately on the dorsum of five Sprague-Dawley rats, and divided into five groups of six flaps. In all groups, graft bed was isolated with silastic sheet. In the group I, all sides of flap were repaired with blockage of silastic sheet insertion. Three, two, and one sides of flap were treated with same method in the group II, III, and IV respectively. Other sides of flaps were repaired without blockage, so all sides of flap were repaired in the group V. At 14 days later, the survived rate of each flap was evaluated according to the numbers of the repair sites. Histological examination was done for the evaluation of new vessel development quantitatively. Overall survived rates were increased with the number of repaired sites, but the group V only showed increased survival rate up to more than fifty percentile of the flap size with a significant difference statistically. New vessels were also increased in proportion with the number of repaired sites, and the repair site more than two had significant effect on the increased number of new vessels. In conclusion, at least more than threefourth of flap circumference should be repaired in order to increase flap survival effectively under the condition of bed isolation.
Animals ; Graft Survival ; Rats ; Rats, Sprague-Dawley ; Survival Rate ; Transplants

There is a persistent shortage of allografts available for transplantation, so we envisioned using non-heart beating donation to expand the donor pool. Non-heart beating donors (NHBD) were categorized using four definitions. Controlled donors, consisting of categories III and IV, are the most suitable for NHBD. Delayed graft function is associated with the use of kidneys from such donors, but had no difference on graft survival in the long-term results compared with heart beating donors. The proportion of NHBD of deceased donors differs considerably among countries, but national programs in many nations have now been initiated to increase the rate of non-heart beating donation. In most cases, the organs from NHBD are not available for transplantation in Korea because of legal restrictions. The use of controlled NHBD is encouraged to expand available allografts in Korea, due to the shortage of such allografts
Delayed Graft Function ; Graft Survival ; Heart ; Humans ; Kidney ; Korea ; Tissue Donors ; Transplantation, Homologous ; Transplants ; Warm Ischemia