1.In vitro studies of immunoglobulin G secretion in cultures of peripheral lymphocytes and function of suppressor T cell in autoimmune thyroid disease
Chinese Journal of Pathophysiology 1989;0(05):-
0.05), but their SR was much lower(P
2.Progress of molecular biology in thyroid carcinoma
International Journal of Surgery 2011;38(2):109-112
Thyroid carcinoma is the most frequent endocrine cancer,and most are found in women.Different pathologic types of thyroid carcinoma has different biologic behaviors,and onset is hidden,which results in difficults to diagnose the early thyroid carcinoma.With the development of the molecular biology,more researches are focus on thyroid carcinoma in recent years.This article reviews the tumor markers,oncogene and gene therapy of thyroid carcinoma.
3.A Meta-analysis about early results of small J-pouch versus straight anastomosis after low anterior resection for rectal cancer
Chinese Journal of Current Advances in General Surgery 1999;0(04):-
0.05).The comparison of operating time and hospital stay was not performed due to insufficient data.Conclusion:Relative small J-pouch and straight anastomos is provided similar early results after low anterior resection.Both of these methods were proved to be safe and effective.
4.Employment analysis of graduates in biomedical engineering specialty
Chinese Medical Equipment Journal 2015;(9):144-146,152
Mass data is absent for the employment of the graduates in biomedical engineering specialty in China. Questionnaire was carried out in the graduates from 1989 to 2013 in School of Biological Sciences & Medical Engineering of Southeast University, and more than 1 500 questionnaires on the graduate employment were classified, summarized and analyzed to provide instructions for graduate employment guidance and student education in biomedical engineering specialty.
5.Advances of the long-term medication adherence in the children with bronchial asthma
International Journal of Pediatrics 2016;43(1):33-35,40
Asthma is the most common chronic inflammatory airway disease in childhood. Adhering to a daily anti-inflammatory treatment is the most important cornerstone of bronchial asthma control. However,with the large number of clinical studies conducted in recent years,learning inhaled corticosteroids as an anti-inflam-matory drug of choice,there is a mixed compliance rate of inhaled corticosteroids in children. Standard treatment and control of asthma has yet to be further improved. This review discusses the medication adherence to long-term inhaled corticosteroid as well as the relevant aspects of research progress.
6.The analysis of the calcification in differentiating malignant thyroid neoplasm and the molecular mechanisms for the formation of the calcification.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(16):763-766
The purpose of this review is to investigate the value of the calcification in differentiating malignant thyroid neoplasm and the molecular mechanisms for the formation of the calcification. Many published reports have proved the presence of calcifications in thyroid neoplasm and calcified nodules in these studies are more frequently malignant than noncalcified nodules. Through viewing the related references, we found that psammoma bodies (PBs), Runx2, osteocalcin, osteopontin, CD44v6 play an important role in the molecular mechanisms in the formation of the calcification in PTC. But further study is required for elucidating the mode of action.
Calcinosis
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diagnosis
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pathology
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Core Binding Factor Alpha 1 Subunit
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metabolism
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Humans
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Hyaluronan Receptors
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metabolism
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Osteocalcin
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metabolism
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Osteopontin
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metabolism
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Thyroid Neoplasms
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diagnosis
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pathology
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Thyroid Nodule
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pathology
7.A comparison study on auditory verbal learning ability among four different brain areas after stroke
Chinese Journal of Geriatrics 2012;31(2):105-109
Objective To compare the ability of auditory verbal learning,memory and retention between each side of thalamus and basal ganglia after stroke.Methods 63 patients with single lesion in thalamus or basal ganglia after stroke,34 patients with amnestic mild cognitive impairment (aMCI)and 34 healthy control subjects received auditory verbal learning test.Results There was an overall decline of immediate and delayed recall,retention ability in patients with single lesion of stroke as compared with the healthy control group(P<0.05).Both the left thalamic stroke group [(19.0± 3.1)scores]and aMCI group[(17.6 ±3.3)scores]showed similar pattern in damaged recognition ability,while this ability still existed in the other three stroke groups.The ability of auditory verbal learning in the left thalamic stroke group[(2.2 ± 2.0)scores]and right thalamic stroke group[(2.1 ± 1.9)scores]were lower than in the healthy control group[(3.6 ± 1.8)scores](P <0.05).The retention ability in the left thalamus stroke group[(2.8±1.7)scores]and the right basal ganglia stroke group[(2.7 ± 1.9)scores]was decreased than in the healthy control group[(1.7±1.4)scores](P<0.05).Conclusions There is decline of AVLT-learning,memory and retention ability in patients with single lesion stroke,especially in the left thalamus stroke patients.Moreover,the pattern of impairment in the left thalamus stroke is similar to aMCI but different from the other three stroke groups.
8.The fourth long-term follow-up study of 72 patients with transient ischemic attacks
Chinese Journal of Geriatrics 2001;20(2):85-88
Objective In order to observe the long-term follow-up of 72 patients with transient ischemic attack(TIA),including the recurrence of TIA after the first attack, occurrence of complete stroke and myocardial infarction, fatality rate, causes of death, and the survival rate in each year and its 95% confidence interval, and to evaluate the clinical significance of neurovascular surgical indication. Methods Seventy-two patients with TIA collected from 1959 to 1977 were followed up by means of face-to-face communication with the patients themselves or their families till 1998. And those aspects mentioned above were analyzed with the methods of cohort study, life table and other medical epidemiological statistics. Results The recurrent rate of TIA in 72 patients was 27.9%, and the occurrence rate of complete stroke 65.7%, and that of the myocardial infarction and the fatality 8.4% and 72.7%, respectively. There were 2(3.8%) patients died of myocardial infarction. It was showed from the study that the main cause of death was complete stroke, accounting for 59.6% of all dead patients, with the first cause in non-elderly patients was cerebral hemorrhage and that in the elderly patients was cerebral infarction. The 20-year survival rate was 39.9% and its 95% confidence interval was (28.4%,51.4%). Nineteen cases had the indication of neurovascular surgical operation, accounting for 26.6% of all 72 patients. Conclusions In the long-term follow-up study, the prognosis of patients with TIA was better than that of those with cerebral infarction. About one third of patients had the recurrence of TIA. The occurrence rate of the complete stroke was obviously higher than that of the myocardial infarction. It was considered that neurovascular surgical operation for preventing the happening of complete stroke in patients with TIA was limited.
9.Progress of neoadjuvant chemotherapy for pancreatic cancer
International Journal of Surgery 2009;36(5):335-338
Surgical treatment has improved the prognosis of resectable pancreatic cancer considerably de-spite the generally aggressive behavior of its malignancy. Neoadjuvant therapy for pancreatic cancer has been shown effective in improving a survival benefit. Few prospective randomized controlled clinical trials (RCTs) on the use of neoadjuvant chemotherapy and chemoradiation has been done tp show the survival advantage of systemic chemotherapy (5-FU/FA or gemcitabine) following surgical resection. Up to now, there is no high-level evidence of any benefit deriving from neoadjuvant chemo therapy for pancreatic cancer. Well designed trials are needed to compare neoadjuvant chemotherapy with surgery to judge the value of neoadjuvant cherqo-therapy in multimodal treatment concepts of pancreatic cancer.
10.The analysis of effects and complications of cervical spondylotic myelopathy(CSM)treated with de compression by two different approaches
Chinese Journal of Orthopaedics 2008;28(9):714-719
Objective To analyze functional improvement of spinal cord and the prognosis of two surgical approaches for the stenosis of cervical spinal canal;to investigate the mechanisms concerning post-terior decompression,fusion with ilium graft and internal fixation and 158 cases who underwent dorsal laminectomy from January 2001 to October 2002 were follow-up for at least 24 months and examined with the evaluation systems of Japanese Orthopaedic Association Score,somatosensary evoked essential and initiative range of motion to compare preoperative,short-term and long-term efficacy.Results According to selected standard of improvement rate,therapeutic effect of 56 sufferers among ventral approach group was analyzed,14 cases(25%)excellent,29 cases(51.79%)good,10 cases(17.86%)fair,3 cases(5.36%)poor;postoperative effect of 62 sufferers from dorsal approach group was analyzed,23 cases(37.10%)excellent,31 cases(50%)good,7 cases(11.29%)fair,1 case(1.61%)poor.Concerning JOA evaluation of spinal cord function,initiative range of motion and correlated parameters of SEP,there was significant difference between two decompression approach in postoperative periods.7 cases from anterior approach and 13 patients from posterior approach disturbed by postoperative complications were gradually rehabilitated through conservative of Cervical 5 spinal root',the essence of above-mentioned symptoms may be cervical cord impairment due to decompression process,which would be alleviated by appropriate intervention;2)The efficiency of posterior decompression get the better of anterior decompression in light of fundamentally enlarging available space approach became a little smaller than normal individuals,however,the corresponding parameters after anterior approach lower than the former two groups.