Objective: To introduce the centralized management method for the conventional medical equipment and its utilization benefits and economic benefits to hospital and clinical department through scientific management pattern. Methods: Through several parts such as utilization ratio, usage cost, daily maintenance, measure control and data analysis, they could explain the advantage and convenience after proceeding centralized management. Results:Reasonable and scientific centralized management pattern could reduce or wipeout the idle and waste phenomenon for conventional medical equipment, reduce the department's expenditure of equipment depreciation, enhance the economic efficiency to hospital and clinical department. Through timely preventive maintenance and measure control, not only could save the precious time for the service staff to share personal experience, enhance the equipment repair time and repair rate effectively, but also could guarantee the equipment operation status and operation stability, protect the safety of patient medical device's usage. Conclusion:By making full use of various valuable data, it could be the reference point for these device's analysis and evaluation. As a result, concluded from economic, safety and scientific research part, it is necessary to promote centralized management for the conventional medical equipment.

Objective:To elaborate the operation training process and assessment mechanism of medical equipment, emphasizing the medical device operation should be people-oriented, the use of advanced medical equipment must be after through the improvement training and strict examination, adhere to standardized processes, flexible thinking and methods to operating the medical equipment. So that, makes medical equipment to achieve the desired functionality. Methods: By dividing the kind of related personnel of medical equipment, to illustrate the corresponding training and assessment standards level of each staff. Fully mobilize the working enthusiasm of staff, make them pay attention to the normative operation, and change the values of medical equipment for medical staffs, by using the appropriate rewards and punishment system.Results: The medical equipment operation of operating personnel who participate the appropriate training and grade evaluation could conform to the assessment standards. Conclusion: The safety and effectiveness of medical equipment can be effectively improved by upgrade the operating levels of using staffs, it is effectively extending the medical equipment service life and saving the medical equipment cost while upgrading the overall quality of medical cared by the hospital. It makes further sustainable development of hospital.

Objective:To compare the dissolution results of doxazosin mesylate extended release tablets determined by a fiber-optic method and the imported drug registration standard method. Methods:The drug release process was determined directly with a FODT-601 fiber-optic medicine dissolution/ release rate process monitoring system. Aqueous solution of hydrochloric acid and sodium chloride was used as the dissolution medium, the paddle rotation rate was 75 r·min-1 , the detection wavelength was set at 246 nm while the reference wavelength was 550 nm. The detection length was 5 mm. Results:The standard curve of doxazosin mesylate was linear within the concentration range of 0. 468 1-11. 700 0μg·ml-1 and r values were greater than 0. 999 0. The intra-and inter-day RSD (n=6) was 1. 6% and 2. 0%, respectively. The recovery of doxazosin mesylate was 99. 0% and RSD was 1. 4(n=9). The results determined by the fiber-optic method were generally higher than those determined by the standard method, and there were some differences in the measurement results. Conclusion:Fiber-optic method shows the whole dissolution process objectively. It is particularly prominent in the research on the dissolution of rapid, extended and controlled release preparations. However, it can not replace the standard method yet.

This study is based on the application of the medical simulator and the multimedia technology to the medical English teaching for overseas students during their clinical practice in surgical department.It shows that this teaching model is effective by delivering a good studying surroundings and various language carriers.

The RhD antigen is expressed only in human red blood cells (RBC).Its immunogenicity and clinical application are only next to ABO blood group system, and is widely used both for blood typing and prevention of hemolytic disease of the newborn. The traditional anti-Rh(D) is derived by fractionation of plasma from individuals who have been sensitized by pregnancy or transfusion, or have been deliberately immunized to produce anti-Rh(D). Because of the limited source of plasma, researchers began the study of monoclonal and recombinant antibody. Monoclonal and recombinant anti-Rh(D) antibodies may provide alternatives to the current plasma derived polyclonal IgG anti-Rh(D), but up to now,none of them have yet proved effective in humans for prevention of RhD immunity and hemolytic disease of the newborn.

Recently, a benign variant of scleroderma, called the C.R.S. T, syndrome, has ben ibed by Winterbauer. Patients with this disorder have skin changes such as Cermal and subr,utaneous calcinosis, Raynauds phenomenon, sclerodactyly, and te1angiectasia. With the passible exception. of the gastroirgestinal syaterh, involvernent of other organs is uncommon, and affected. individuals have a Iong clinical cgurse. A case of C.R.S.T. syndrome in 25-year-old femala in reported with brief reviev of literatures. The patient showed miultiple pea sized nodular depoaits on dermal and subcuta.neous layers of both elbow and. knee joints, Rayaauds phenamenon, sclerrodactyly with acroselerosis and sclerodermatous change on both hands and forearm and telangiectasia on face and both palms On eeophagogram, slight disturhance of passage at the cardioesophageal junetion area was noted.
Adult ; Calcinosis ; Elbow ; Forearm ; Hand ; Humans ; Knee Joint ; Peas ; Skin ; Telangiectasis

Objective To establish the procedural pain nursing care protocols to improve the management of perioperative pain in elderly patients after total knee replacement,as well as to relief postoperative pain,and promote the rehabilitation.Methods 82 patients were randomly divided into the control group (45 cases) and the intervention group (37 cases).The control group was controlled by usual care,and the intervention group was offered with the standardized pain nursing care.The scores for postoperative pain,the satisfaction for analgesia,the complications associated with analgesia and the injection rate of Dolantin at 24,48,72h postoperatively were compared between two groups.Results The score for postoperative pain at rest in the intervention group was significantly lower than that in the control group at 24 h postoperatively,but there was no statistical difference at 48 h and 72 h postoperatively.Pain scores during passive activity at 24,48h,and 72h postoperatively were significantly lower in the intervention group when compared with that of the control group.The rates of side effects at 24,48,72h postoperatively in the intervention group were significantly lower than those in the control group.The injection rate of Dolantin in the control group were significantly higher than that in the intervention group.The score for both analgesia and life satisfactory in the intervention group was significantly higher than that in the intervention group at 24,48,72h postoperatively.Conclusions Procedural pain nursing care can reduce the pestoperative pain,complications and the injection rate of Dolantin in patients after total knee replacement.It can also improve elderly patients' satisfaction of analgesia and promote early recovery of their joint function.

Drug-induced nephrotoxicity is very common in both new drug development and clinic practice. Various drugs can induce kidney injuries, including tubulointerstitial, glomerular and renal vascular disease. To investigate the mechanism of drug induced nephrotoxicity is important for risk reduction of new drug development, reasonable drug usage, early discovery and effective prevention/treatment of adverse effects in clinics.

Objective To observe the clinical efficacy of abdominal acupuncture plus moxibustion in treating cervical spondylosis of vertebral artery type.Method A hundred patients with cervical spondylosis of vertebral artery type were randomized into a treatment group and a control group, 50 cases in each group. The control group was intervened by abdominal acupuncture plus electroacupuncture; while the treatment group was by moxibustion in addition to the treatment given to the control group. After a treatment course, the onset and remission time of vertigo was observed, and the clinical efficacies were compared between the two groups.Result The total effective rate was 96.0% in the treatment group versus 93.8% in the control group, and the difference was statistically significant (P<0.05). There was a significant difference in comparing the onset and remission time of vertigo between the two groups (P<0.05). In comparing the relapse rates 3, 6, and 12 months after the intervention between the two groups, the difference were statistically significant (P<0.01).Conclusion Abdominal acupuncture plus moxibustion is an effective approach in treating cervical spondylosis of vertebral artery type.

PurposeCT myelography (CTM) and gadolinium-enhanced MR myelography (Gd-MRM) are essential methods used for localizing spinal cerebrospinal fluid leaks in patients with spontaneous intracranial hypotension (SIH) and are significant for diagnosis and guided epidural blood patches. This paper analyzes the rate and imaging features of unsuccessful myelography due to misinjection of contrast into epidural space to guide prompt and correct clinical judgment of unsuccessful myelography.Materials and Methods Myelography from 121 patients with SIH was retrospectively reviewed and the image features of the unsuccessful myelography were analyzed.Results A total of 128 myelography examinations were done. Contrast media was accidently injected into the epidural space in 33 examinations. The failure rate was 25.8%. In all 33 failed exams, bilateral spinal nerve roots on both sides of the dural sac passing through contrast media was observed without visualization of anterior and posterior nerve roots. Cauda equina was not seen within contrast media in 29 cases (87.9%); non-diffusion of contrast media into cisterns and ventricles in 26 cases (78.8%). Contrast was not continuous in spinal canal in 16 cases (48.5%), heterogeneous in 10 cases (30.3%). In 4 cases (12.1%) the inner contour of contrast was not smooth.Conclusion The unsuccessful rate of myelography is relatively high in SIH patients. A prompt and correct decision could be made based on the knowledge of contrast misinjection imaging features.