Objective: : Peripheral nerve injuries occur mostly as a result of mechanical trauma. Due to the microvascular deterioration in peripheral nerve damage, it becomes challenging to remove free oxygen radicals. Gallic acid is a powerful antioxidant with anti-inflammatory effects and a free radical scavenger. The purpose of the study is to show that gallic acid contributes to the restorative effect in mechanical nerve damage, considering its antioxidant and anti-inflammatory effects. Methods: : Thirty male Sprague Dawley albino mature rats were included in the study. Ten of them constituted the control group, 10 out of 20 rats for which sciatic nerve damage was caused, constituted the saline group, and 10 formed the gallic acid group. Post-treatment motor functions, histological, immunohistochemical, and biochemical parameters of the rats were evaluated. Results: : Compared to the surgery+saline group, lower compound muscle action potential (CMAP) latency, higher CMAP amplitude, and higher inclined plane test values were found in the surgery+gallic acid group. Similarly, a higher nerve growth factor (NGF) percentage, a higher number of axons, and a lower percentage of fibrosis scores were observed in the surgery+gallic acid group. Finally, lower tissue malondialdehyde (MDA) and higher heat shock protein-70 (HSP-70) values were determined in the surgery+gallic acid group. Conclusion : Gallic acid positively affects peripheral nerve injury healing due to its anti-inflammatory and antioxidant effects. It has been thought that gallic acid can be used as a supportive treatment in peripheral nerve damage.

STUDY DESIGN: Prospective study. PURPOSE: To investigate the cross-cultural adaptation, validity, and reliability of the Turkish version of the Back Pain Functional Scale (BPFS). OVERVIEW OF LITERATURE: Low back pain is a common disorder in the population that negatively affects the patient’s daily, professional, and social life. Self-report questionnaires are important to precisely evaluate back pain and making better and appropriate treatment decisions. Currently, there are several questionnaires for investigating mobility in patients with low back pain. METHODS: We recruited 360 patients with chronic low back pain. For assessing the reliability of the scale, we performed test–retest and internal consistency analyses. Test–retest analysis was performed using intraclass correlation coefficient (ICC). Internal consistency was analyzed by calculating Cronbach’s alpha value. Construct validity of the questionnaire was evaluated by comparing total scores on the BPFS with those on Roland Morris Disability Questionnaire (RMDQ) and Oswestry Disability Index (ODI) using Pearson’s correlation coefficient analysis. RESULTS: Cronbach’s alpha value was 0.910, indicating high internal consistency. The test–retest reliability was excellent (ICC, 0.958; 95% confidence interval, 0.710–0.908). No floor or ceiling effects were observed. Factor analysis indicated that the scale had a single-factor structure. Pearson correlation coefficient was −0.669 when BPFS was compared with RMDQ and −0.701 when compared with ODI. These values indicate a significant correlation of BPFS with RMDQ and ODI. CONCLUSIONS: These data indicate the validity and reliability of the Turkish version of the BPFS.
Back Pain ; Humans ; Low Back Pain ; Prospective Studies ; Reproducibility of Results

Choroidal fissure cysts are often incidentally discovered. They are usually asymptomatic. The authors report a case of growing and hemorrhagic choroidal fissure cyst which was treated surgically. A 22-year-old female presented with headache. Cranial MRI showed a left-sided choroidal fissure cyst. Follow-up MRI showed that the size of the cyst had increased gradually. Twenty months later, the patient was admitted to our emergency department with severe headache. MRI and CT showed an intracystic hematoma. Although such cysts usually have a benign course without symptoms and progression, they may rarely present with intracystic hemorrhage, enlargement of the cyst and increasing symptomatology.
Choroid* ; Emergency Service, Hospital ; Female ; Follow-Up Studies ; Headache ; Hematoma ; Hemorrhage ; Humans ; Magnetic Resonance Imaging ; Temporal Lobe ; Young Adult

Objective: : The aim of this study to investigate the benefits of patient-based 3-dimensional (3D) cerebral arteriovenous malformation (AVM) models for preoperative surgical planning and education. Methods: : Fifteen patients were operated on for AVMs between 2015 and 2019 with patient-based 3D models. Ten patients’ preoperative cranial angiogram screenings were evaluated preoperatively or perioperatively via patient-based 3D models. Two patients needed emergent surgical intervention; their models were solely designed based on their AVMs and used during the operation. However, the other patients who underwent elective surgery had the modeling starting from the skull base. These models were used both preoperatively and perioperatively. The benefits of patients arising from treatment with these models were evaluated via patient files and radiological data. Results: : Fifteen patients (10 males and five females) between 16 and 66 years underwent surgery. The mean age of the patients was 40.0±14.72. The most frequent symptom patients observed were headaches. Four patients had intracranial bleeding; the symptom of admission was a loss of consciousness. Two patients (13.3%) belonged to Spetzler-Martin (SM) grade I, four (26.7%) belonged to SM grade II, eight (53.3%) belonged to SM grade III, and one (6.7%) belonged to SM grade IV. The mean operation duration was 3.44±0.47 hours. Three patients (20%) developed transient neurologic deficits postoperatively, whereas three other patients died (20%). Conclusion : Several technological innovations have emerged in recent years to reduce undesired outcomes and support the surgical team. For example, 3D models have been employed in various surgical procedures in the last decade. The routine usage of patient-based 3D models will not only support better surgical planning and practice, but it will also be useful in educating assistants and explaining the situation to the patient as well.