Objective To investigate the correlativity between social support system and the job burnout of the doctor-nurse group. Methods 240 clinical doctors and nurses of XiaoGan City-Owned hospital of Hubei Province were randomly selected to conduct professional burnout inventory (MBI) and social support assessment questionnaire(SSRS) surveys, thus to investigate the correlativity between social support system and the job burnout of doctor-nurse groups. Results Scores of the emotional exhaustion in the job burnout of the doctor-nurse group were higher and in personal sense of achievement were lower than the normal model Maslach respectively, the difference was statistically significant (P all <0.01); The burnout level of nurses was significantly higher than doctors, of which the emotional exhaustion and personal sense of achievement were significantly different between doctors and nurses (P all <0.01); For social support, there were significantly differences between the scores of the subjective support and those of total support two-dimensionally (P all <0. 01); the three-dimension of social support and totul scores were significant negative correlative to the job burnout emotional exhaustions, and were significant positive correlative to personal sense of achievement. Conclusions The job burnout level in the doctor-nurse group, especially in nurses were rather higher. These should be attracted great attention by managers. It is suggested that proper interference in the doctor-nurse group should be brought out and social support system should be consummated, in addition, professional training needs to be conducted with the seek of favorable social support.