Glottis ; pathology ; Humans ; Laryngeal Diseases ; surgery ; Stents

Glottis ; pathology ; Humans ; Laryngeal Neoplasms ; surgery ; Minimally Invasive Surgical Procedures

OBJECTIVE: To investigate the clinical feature, diagnose and therapeutic methods of paraglottic space primary paraganglioma. METHOD: One case of paraglottic space primary paraganglioma was reported and the relevant literatures were reviewed. RESULT: One case showed a hoarse voice, who was cured after the surgery of neck incision. NSE and CgA were positively expressed. CONCLUSION Paraganglioma of the paraglottic space is very rare. The diagnosis of paraglottic space primary paraganglioma bases on histopathology and immunohistochemistry. The immunohistochemistry and clinical character must be comprehensively analyzed to increase the diagnosis accuracy.
Female ; Glottis ; pathology ; Humans ; Middle Aged ; Paraganglioma ; pathology ; surgery

Subglottic cyst is a rare cause of laryngeal tinnitus in infants and young children, and only a few cases have been reported at home and abroad. In this paper, we report the clinical characteristics and treatment experience of three cases of subglottic cysts in Children's Hospital of Nanjing Medical University. All the 3 childrem were prematurechildren, with a history of tracheal intubation, and the main symptoms were coughing and wheezing.Electronic nasopharyngolaryngoscopy revealed spherical neoplasm under the glottis. Neck computed tomography （CT） showed a slightly hypodense shadow with poorly defined borders, and no significant enhancement was observed after enhancement. Under the self-retaining laryngoscope, the new organisms were clamped and nibbled, and the cyst wall was cauterized by low temperature plasma. There was no recurrence in postoperative follow-up.
Child, Preschool ; Humans ; Infant ; Cysts/surgery* ; Glottis/surgery* ; Laryngeal Diseases/surgery* ; Laryngoscopy/methods* ; Larynx

OBJECTIVETo investigate the clinical features, minimally invasive treatment, and outcomes of subglottic hemangioma in infants.

METHODSFifteen cases of infantile subglottic hemangioma treated from January 2009 to December 2012 were retrospective analysed. Average time of onset was within 43 days-5 months of age. Seven cases had symptoms of laryngeal obstruction one week after birth, and 8 cases had symptoms within three weeks to six weeks after birth. Fourteen cases were unilateral and 1 case bilateral. No case had tracheotomy. Seven cases were hospitalised after intubation. Of which 5 cases with subglottic hemangiomas who failed to respond to pharmacologic treatment were treated by microdebrider under suspension laryngoscope. Ten cases accepted suction cutter suction.

RESULTSAfter surgery, nine cases were confirmed pathologically as capillary hemangioma. Average bleeding was 1-3 ml during operation, surgery usually lasted 10-15 minutes. No complications were found. Five cases required orotracheal intubation for 24 or 48 h after surgery, and no reintubation or tracheotomy was required in this series. Symptoms such as stridor and inspiratory retraction resolved approximately 12-72 h after surgery. Follow-up was 12-18 months after surgery, no systemic or local complications were observed, and no recurrence.

CONCLUSIONSThe treatment of subglottic hemangioma is individualised. If the tracheal stenoses ≥ 50%, with recurrent infection and acute laryngeal obstruction, removal of tumor with microdebrider is the minimally invasive, safe, simple and effective method with less complications. It is important that the anaesthetist should work well with otolaryngologist during operation.

Female ; Glottis ; Hemangioma, Capillary ; surgery ; Humans ; Infant ; Laryngeal Neoplasms ; surgery ; Male ; Retrospective Studies ; Treatment Outcome

Arytenoid Cartilage ; surgery ; Contraindications ; Glottis ; Humans ; Laryngeal Neoplasms ; pathology ; surgery ; Laryngectomy

OBJECTIVETo evaluate the application of acellular dermal matrix (ADM) in the reconstruction of defect after head and neck tumor resection.

METHODSA total of 75 cases applied with ADM after head and neck tumor resection were reviewed. There were 47 cases of laryngeal carcinoma (glottic 41, supraglottic 3, and infraglottic 3), 5 cases of hypopharyngeal carcinoma, 11 cases of maxillary sinus carcinoma, 9 cases of oral cavity tumor, 3 cases of cervical trachea tumor. Among them 25 cases of laryngeal carcinoma, 4 cases of hypopharyngeal carcinoma, 7 cases maxillary carcinoma, 6 cases oral carcinoma, and one case of cervical trachea malignancy received postoperative adjuvant chemoradiotherapy. The patients were postoperatively followed up from 2 weeks to 3 years.

RESULTSAmong 75 cases, 65 cases, including 40 cases of laryngeal carcinoma, 4 cases of hypopharyngeal carcinoma, 9 cases of oral cavity tumor, 9 cases of maxillary carcinoma and 3 cases trachea tumor, presented with good wound healing without any complication within 3 months; the 47 patients with tracheotomy were decannulated successfully; 2 cases of laryngeal carcinoma and 1 case of hypopharyngeal carcinoma were complicated with pharyngeal fistula, which healed with dressing change, followed by decannulation; 5 cases had laryngeal stenosis and decannulation failed in these patients; and 3 cases of maxillary carcinoma had wound infection.

CONCLUSIONADM application is a easy and feasible method for the repair of the defect after head and neck tumor resection.

Acellular Dermis ; Glottis ; pathology ; Humans ; Hypopharyngeal Neoplasms ; surgery ; Laryngeal Neoplasms ; surgery ; Reconstructive Surgical Procedures

OBJECTIVETo introduce a new surgical technique for the treatment of bilateral vocal cord paralysis.

METHODSTwenty-nine patients with bilateral vocal cord paralysis treated in Dalian Municipal Central Hospital between 2008 and 2012 were retrospectively studied. Coblation assisted arytenoidectomy was performed in all cases. The pre and postoperative glottic measurement and vocal acoustic parameters were analyzed.

RESULTSAll patients were decanulated 1 week after operation. Three months later, the mean glottic area increased from (21.9 +/- 4.7) to (40.3 +/- 5.2) mm2 (t = 5.74. P < 0.05); the width of maximal glottic chink increased from (1.47 +/- 0.37) to (4.82 +/- 0.54) mm (t = 6.24, P < 0.05). Twenty-six patients (89.7%) satisfied with the voice quality. Acoustic parameters (F0, jitter, shimmer) were no significant difference (P > 0. 05) , but there was a significant difference in maximum phonation time (P < 0.05). During three months to 3.5 years follow-up, the patients had a stable airway and effective phonation.

CONCLUSIONSEndoscopic coblation assisted arytenoidectomy is a new surgical method for the treatment of patients with bilateral vocal cord paralysis, which is efficient, minimally invasive and safe.

Arytenoid Cartilage ; surgery ; Endoscopy ; Glottis ; Humans ; Laryngectomy ; Laryngoplasty ; Laryngoscopy ; Phonation ; Vocal Cord Paralysis ; surgery ; Voice Quality

OBJECTIVE: To study clinical characteristics, diagnosis, pathological types and therapy methods of nonsquamous cell neoplasm in subglottis, in order to improve comprehension of this rare disease. METHOD: To analysis 3 patients' clinical data with noosquamous cell neoplasm in subglottis by reviewing related literature, and to generalize the symptoms, differentiation and treatment experience of nonsquamous cell neoplasm in subglottis. RESULT: Among the 3 patients, one's main complain was hoarseness and the other two's main symptom was inspiratory dyspnea. As diagnosis was definite and acute obstruction of airway was relieved, the neoplasms were removed totally. Two patients were undergone operation through oral cavity by using suspended laryngoscope, and one patient was done surgery by neck approach. Paraffin wax result showed that one patient suffered epithelial-myoepithelial carcinoma, who received radiotherapy after surgery. There is no recurrence in all patients by following up more than 1 year. CONCLUSION The occurrence of nonsquamous cell neoplasm in subglottis is relatively low, and the subglottis should be inspected carefully to avoid missed diagnosis. Operation is the preferred method to treat this kind of disease. To choose a suitable operational manner according to size, location of the neoplasm is crucial.
Female ; Glottis ; pathology ; Humans ; Laryngeal Neoplasms ; diagnosis ; pathology ; surgery ; Male ; Middle Aged

OBJECTIVE: To investigate the effectiveness external radiation (XRT) vs transoral laser surgery (TOL) for treatment of early glottic carcinoma. METHOD: Medline (1990-2010), Embase (1990-2010), Cochrane Library, CBM (1990-2010), CNKI (1994-2010), Wanfang Database were searched for published case-control studies investigating the effectiveness external radiation vs transoral laser surgery for treatment of early glottic carcinoma. The odds ratio was calculated. Meta-analyses were performed by RevMan5. 0. 2 Software. RESULT: In the complications of this study, there was significant heterogeneity in the literatures, so Meta analysis was given up. In the recurrence and 5-years locoregional control, XRT group was no significant difference with TOL group by eliminating the heterogeneity or using the subgroup analysis, but the results till showed there was less recurrence and more locoregional control in TOL group than those in XRT group. In death of disease, overall survival and laryngeal preservation, the differences were statistically significant. CONCLUSIONS TOL could be complete in the clinic and the cost was much more cheaper than XRT. So TOL could be used as the first choice for the treatment of early glottic carcinoma versus XRT. But for larger tumors, involving the anterior commissure, there was no clear conclusion. Based on literatures, traditional surgery was the proposed choice. We recognize that the datas included in our study are retrospective studies, for a more scientific conclusion, we need more RCTs.
Glottis ; pathology ; Humans ; Laryngeal Neoplasms ; radiotherapy ; surgery ; Laser Therapy ; Treatment Outcome