1.Pulmonary artery sling: case report.
Gil Hyun SHIN ; Sun Wha LEE ; Sung Ho CHA
Journal of the Korean Radiological Society 1993;29(5):1067-1070
Aberrant left-sided pulmonary artery(pulmonary artery sling) is an uncommon anomaly, which may cause significant respiratory abnormality. We report a case of pulmonary artery sling which is combined with persistent left superior vena cava and dextrocardia. This case was identified by esophagogram and CT and confirmed by MRI and angiography. We consider that MRI is a valuable new method for the diagnosis of aberrant left-sided pulmonary artery.
Angiography
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Arteries
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Dextrocardia
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Diagnosis
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Magnetic Resonance Imaging
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Methods
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Pulmonary Artery*
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Vena Cava, Superior
2.The Study for Relationship of Ocular Surface Abnormalities, Corneal Sensitivity and Diabetic Retinopathy in DM.
Jae Suk KIM ; Gil Wha HYUN ; Nam Ju MOON ; Yoon Kyung KANG ; Do Hyung LEE
Journal of the Korean Ophthalmological Society 2004;45(3):383-389
PURPOSE: To evaluate the correlation between the severity of diabetic retinopathy, decrease of corneal sensitivity and conjunctival impression cytology. METHODS: 150 eyes of 75 patients were enrolled. The patients were divided into two groups. The study group is 110 eyes of 55 patients with diabetic retinopathy and the control group is 40 eyes of 20 patients without diabetic retinopathy. The hemoglobin A1C (HbA1C) and fasting plasma glucose (FPG) were measured for the index of diabetic control. Corneal sensitivity was measured with Cochet-Bonnet aesthesiometer, and conjuctival impression cytology and fundus examination were done in two groups after topical anesthesia instillation. The classification of diabetic retinopathy was based on the ETDRS. RESULTS: In corneal sensitivity, the study group was 3.8 +/- 3.6 g/mm2, the control group 1.1 +/- 2.16 g/mm2, showing statistically significant difference (p<0.05). The severity of diabetic retinopathy had negative correlation with corneal sensitivity (R2=0.26, p<0.05). Conjunctival impression cytology had negative correlation with corneal sensitivity (R2=0.41, p<0.05), and positive correlation with retinopathy (R2=0.26, p<0.05). Corneal sensitivity was affected by the hemoglobin A1C (p<0.01), but fasting plasma glucose (p=0.7). CONCLUSIONS: Conjucntival impression cytology had negaitive correlation with corneal sensitivity and positive correlation with diabetic retinopathy. It can be thought that corneal sensitivity is affected by chronic glycemic control.
Anesthesia
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Blood Glucose
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Classification
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Diabetic Retinopathy*
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Fasting
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Humans
3.Changes in t-PA and PAI-1 levels after exercise in patients with diabetes mellitus: A sex and age-matched control study.
Jung Hye CHOI ; Sun Gil KIM ; Woong Soo LEE ; Tae Wha KIM ; Tae Young KIM ; Jin Ho SHIN ; Jae Ung LEE ; Kyung Soo KIM ; Jeong Hyun KIM ; Heon Kim LIM ; Bang Hun LEE ; Chung Kyun LEE
Korean Journal of Medicine 1999;56(5):606-612
OBJECTIVES: Plasma fibrinolytic activity is determined by the balance between plasmonogen activators and their inhibitors. The aim of this study was to compare the fibrinolytic activity before and after exercise of the type 2 diabetic patients with control group. METHODS: We measured plasma tissue-plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) antigen before and after standardized treadmill exercise in 21 type 2 diabetic patients (14 men, 11 women, ages 46.2+/-5.6 years) and 21 sex and age- matched control group (10 men, 11 women, ages 48.6+/-5.4 years). RESULTS: 1) Post exercise t-PA antigen increased in both diabetic group (from 7.36+/-3.89 to 10.62+/-4.81 ng/ml, p<0.05) and control group (from 8.30+/-3.99 to 10.99+/-5.52 ng/ml, p<0.05). But the rise in t-PA antigen with exercise was similar in both group. 2) Both base line and post exercise PAI-1 antigen levels were similar between the diabetic group (from 29.46+/-10.35 to 31.48+/-12.94 ng/ml, p>0.05) and control group (from 30.04+/-10.40 ng/ml to 31.06+/-10.88 ng/ml, p>0.05). 3) In diabetic group, significant correlations between base line PAI-1 antigen levels and serum triglyceride levels were observed. And post exercise PAI-1 antigen levels were correlated with systolic blood pressure. CONCLUSION: The results show that plasma t-PA antigen level is increased after vigorous exercise in patients with type 2 diabetes mellitus and plasma PAI-1 antigen level is not changed. The increment of plasma t-PA level is not different with healthy subjects.
Blood Pressure
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Diabetes Mellitus*
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Diabetes Mellitus, Type 2
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Female
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Humans
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Male
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Plasma
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Plasminogen Activator Inhibitor 1*
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Plasminogen Activators
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Triglycerides
4.Differences of Zebrin II Expression Pattern Between Normal Balb/C and Ataxic Pogo Mouse Cerebellum.
Nam Seob LEE ; Chul Tae KIM ; Ki Hyung KIM ; Sun Kyung KIM ; Seung Hyuk CHUNG ; Kyong Og KO ; Kazuhiko SAWADA ; Yoshihiro FUKUI ; Byung Wha HYUN ; Moo Ho WON ; Young Gil JEONG
Korean Journal of Anatomy 2003;36(6):457-462
The purpose of this study is to identify the differences of zebrin II expression between ataxic pogo and normal Balb/C mouse cerebellum. Zebrin II is expressed by subsets of Purkinje cells that form an array of parasagittal bands that extend rostrocaudally throughout the cerebellar cortex, separated by similar bands of Purkinje cells that do not express zebrin II. Zebrin II immunoreactivity was localized in the perikarya of Purkinje cells, and the dendrites. Distribution of zebrin II-immunoreactive Purkinje cells were very similar pattern in pogo and Balb/C mouse cerebellum. But, in the lobule III, distribution of zebrin II expression was different between pogo and Balb/C mouse cerebellum. In lobule III of Balb/c mouse cerebellum, 10~15 zebrin II-immunoreactive Purkinje cells were observed and clustered to form a parasagittal bands. On the other hand, zebrin II expressions of lobule III in pogo mouse cerebellum showed a little different patterns. In lobule III of pogo mouse cerebellum, three bilateral zebrin II immunoreactive parasagittal band were observed. P1 band was almost same with lobule III of Balb/C mouse cerebellum. But, P2 bands were composed of 50~60 Purkinje cells which were immunoreactive with zebrin II. These kind of thickening in zebrin II expression of pogo mouse cerebellum may be due to the genetical difference. Furthermore, these results may provide useful information with further ataxic pogo mice cerebellum studies.
Animals
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Cerebellar Cortex
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Cerebellum*
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Dendrites
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Hand
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Immunohistochemistry
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Mice*
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Purkinje Cells