2.Paraneoplastic relapsing minimal change disease associated with type A thymoma in an elderly patient: A case report and literature review
Clara Lee Ying Ngoh ; Giap Hean Shaun Goh ; Weng Kin Wong
The Medical Journal of Malaysia 2019;74(1):97-98
Thymoma is a rare mediastinal tumour that can be
accompanied by different paraneoplastic syndromes. Here
we report a case of Type A thymoma associated with
relapsing minimal change disease (MCD). This case
highlights: (1) The need to balance rapid prednisolone
weaning against risk for relapse in an elderly patient at risk
for steroid-induced complications. (2) The addition of
calcineurin inhibitor in relapsed thymoma-related MCD, to
achieve steroid sparing effects. Resection of the offending
tumour and prompt immunosuppressive therapy are critical
in getting best renal and overall outcomes in this rare entity