1.Dynamic CT Findings of Bilateral Castleman Disease in the Neck: A Case Report.
Hyung Jin KIM ; Jae Soo KIM ; Eui Gee HWANG ; Won Hong KIM
Journal of the Korean Radiological Society 1997;37(5):797-800
We present a case of hyaline vascular type Castleman disease involving the bilateral cervical lymph nodes. To our knowledge, no previous case of this localized form of the disease has been reported. Dynamic CT demonstrated a hypervascular pattern of enhancement, with central less enhanced areas that corresponded histologically to fibrosis. For the diagnosis of this uncommon lymph node disease, these findings might be helpful.
Diagnosis
;
Fibrosis
;
Giant Lymph Node Hyperplasia*
;
Hyalin
;
Lymph Nodes
;
Neck*
2.A Case of Castleman's Disease Presenting as an Isolated Hypervascular Tumor in Neck.
Eun Jin SON ; Yoon Jae LEE ; Ja Seung KOO ; Hong Shik CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 2004;47(11):1178-1180
Castleman's disease is an unusual condition of lymphoproliferation, still a rarer cause of isolated neck mass. Also known as angiofollicular lymph node hyperplasia, it is a pathological diagnosis, with three histologic variants (hyaline vascular, plasma-cell, and mixed) and two clinical types (localized and multicentric). We present a case of an isolated neck mass of long standing, which was treated by surgical excision and histopathologically confirmed as hyaline vascular type of Castleman's disease. The lesion showed distinct hypervascular features on imaging studies. Castleman's disease should be considered as a differential diagnosis in isolated hypervascular neck masses.
Diagnosis
;
Diagnosis, Differential
;
Giant Lymph Node Hyperplasia*
;
Hyalin
;
Neck*
3.Retroperitoneal Castleman's Disease Incidentally Detected due to Urinary Calculus.
Jung Woo LEE ; Sung Yul PARK ; Byung Seok KIM ; Sang Jin KIM ; Young Woo SON ; Hong Sang MOON ; Chan Kum PARK ; Tchun Yong LEE
Korean Journal of Urology 2008;49(2):186-189
Castleman's disease(CD) is a rare benign tumor characterized by hyperplasia of lymphoid tissue. It can occur in almost any l ocation, with 70% in the mediastinum, 7% in the retroperitoneum, and only 2% in the perirenal area. Approximately 80% of primary retroperitoneal tumors are malignant, so tumor resection and differential diagnosis with other retroperitoneal tumors is important. We present a case of a hyaline-vascular type CD in the pararenal area, detected incidentally during evaluation of a urinary calculus, with a review of the literature.
Diagnosis, Differential
;
Giant Lymph Node Hyperplasia
;
Hyperplasia
;
Lymphoid Tissue
;
Mediastinum
;
Urinary Calculi
4.Surgical Management of Unicentric Castleman's Disease in the Abdomen.
Min Sang KIM ; Jae Kyun JU ; Young KIM
Annals of Coloproctology 2014;30(2):97-100
Castleman's disease (CD) is a rare lymphoproliferative disorder that can involve single or multiple lymph nodes in the body. Especially, the localized form of CD is known to be well-controlled by using a surgical resection. On occasion, the surgeon may confront an abdominal and retroperitoneal mass of unknown origin. Thus, we present this case in which we treated a 16-year-old female patient for CD and investigated how to evaluate and manage the situation from the standpoint of CD. Also, we give a review of the pathology, clinical manifestation, diagnosis, and treatment of CD.
Abdomen*
;
Adolescent
;
Diagnosis
;
Female
;
Giant Lymph Node Hyperplasia*
;
Humans
;
Lymph Nodes
;
Lymphoproliferative Disorders
;
Pathology, Clinical
5.Castleman's Disease (Giant Lymph Node Hyperplasia): Report of 2 cases and review of the literature.
Woo Young SOHN ; Myung Suk SIM ; Dong Seon PARK ; Jin Kook KANG
Journal of the Korean Surgical Society 1997;53(1):138-145
Two cases of Castleman's disease (Giant lymph node hyperplasia) are reported. The first case was a multicentric cervical giant lymph node hyperplasia. Excisional biopsy confirmed the diagnosis of Castleman's disease of the plasma-cell type. Despite repeated dissection of the cervical lymph nodes, complete removal of the lymph nodes was impossible, and the type was changed into mixed type, and regrowth of the tumor was noted. Prednisolone was of no benefit. The patient is now living with cervical masses in situ without general symptoms, 4 years after the initial diagnopsis. The second case was a solitary retroperitoneal giant lymph node hyperplasia, incidentally found. Complete excision was performed and biopsy confirmed the diagnosis of Castleman's disease of hyaline-vascular type. No recurrence was found at 2 years after the excision.
Biopsy
;
Diagnosis
;
Giant Lymph Node Hyperplasia*
;
Humans
;
Lymph Nodes*
;
Neck
;
Prednisolone
;
Recurrence
6.A Case Report of Castleman's Disease(Giant Lymph Node Hyperplasia) Presenting as a Isolated Neck Mass.
See Young PARK ; Sang Chul KIM ; Young Seung KO ; Seung Bum KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 2004;47(9):935-938
Castleman's disease, a benign lymphoproliferative disease of unknown etiology, rarely occures as a neck mass. Only 6% of the cases reported in the literature was detected primarily in the neck. This disease consists of unicentric or multicentric (or systemic) forms by clinical manifestation and hyaline vascular type or plasma cell type, histologically. The more common hyaline vascular type usually presents as an asymptomatic lymphoid mass. On the other hand, in plasma cell type, systemic manifestations are frequently observed. Definite diagnosis and treatment is possible with complete surgical resection following histologic evaluation. Recently, we experienced a 22 year old woman patient with 5 year history of right neck mass. She underwent surgical mass resection. Pathologic analysis confirmed hyaline vascular variant of Castleman's disease. Now, we report this case with a review of previously reported literature.
Diagnosis
;
Female
;
Giant Lymph Node Hyperplasia
;
Hand
;
Humans
;
Hyalin
;
Lymph Nodes*
;
Neck*
;
Plasma Cells
;
Young Adult
7.MRI Findings of Cervical Lymphadenopathy: Preliminary Study.
Young Chil CHOI ; Sung Sik OH ; Yeon Ok LEE ; Ji Yean LEE ; Young Ja CHO ; Byung Lyul PARK ; Koung Hee LEE
Journal of the Korean Radiological Society 1994;31(2):197-203
PURPOSE: The purpose of this study is to evaluate findings in MRI which maybe useful in differential diagnosis of cervical lymph node enlargement. MATERIALS AND METHODS: We retrospectively analyzed the MRI findings of cervical lymph node enlargement in surgically proven 13 patients. We analyzed the location, size and shape, signal intensity, margin between node and surrounding structures degree and patterns of contrast enhancement RESULTS: No disease specificity in location and size of lymphadenopathy. was demonstrated in MRI. Most lymph nodes shows isointensity or slightly increased signal intensity to adjacent muscle on T1WI and high signal intensity on T2WI. Most of the cases showed contrast enhancement with metastatic lymph nodes showing ring-like and/or patchy enhancement. Tuberculous lymphadenopathy showed homogeneous or rather thick walled ring-like enhancement and one or multiple central nonenhancing portions of eccentrical location in the node. Relatively homogeneous enhancements were noted on reactive lymphold hyperplasia, Lymphoma and Castleman's disease. CONCLUSION: MR imaging was helpful in differentiation of cervical lymph node enlargements. Tuberculous lymphadenopathy showed characteristic findings of rather spherical shaped, thick walled ring enhancement and multiple eccentrically located central nonenhancing portions.
Diagnosis, Differential
;
Giant Lymph Node Hyperplasia
;
Humans
;
Hyperplasia
;
Lymph Nodes
;
Lymphatic Diseases*
;
Lymphoma
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Sensitivity and Specificity
8.Castleman's Disease of the Renal Sinus Presenting as a Urothelial Malignancy: A Brief Case Report.
Se Min JANG ; Hulin HAN ; Ki Seok JANG ; Young Jin JUN ; Tchun Yong LEE ; Seung Sam PAIK
Korean Journal of Pathology 2012;46(5):503-506
Castleman's disease is a rare benign lymphoproliferative disorder that frequently affects lymph nodes of the mediastinal thorax and the neck. It very rarely affects the renal sinus. We report a case of Castleman's disease arising in the renal sinus in a 64-year-old man. The patient visited the hospital with the chief complaint of hematuria. Abdominal computed tomography revealed a homogeneous mass in the sinus of the left kidney, radiologically interpreted as a malignant urothelial tumor. Subsequently, nephroureterectomy was performed, after which microscopic examination of the specimen revealed a diffuse lymphoproliferative lesion with reactive lymphoid follicles of various sizes and prominent plasma cell infiltration of interfollicular spaces, highlighted by immunohistochemical staining for CD138. The lesion was diagnosed as Castleman's disease of the plasma cell type. Although preoperative diagnosis of Castleman's disease is difficult and the incidence is exceedingly rare, it should be considered in the differential diagnosis of renal sinus tumors.
Diagnosis, Differential
;
Giant Lymph Node Hyperplasia
;
Hematuria
;
Humans
;
Incidence
;
Kidney
;
Lymph Nodes
;
Lymphoproliferative Disorders
;
Middle Aged
;
Neck
;
Plasma Cells
;
Thorax
9.Hyaline Vascular-Type Castleman Disease Presenting as an Esophageal Submucosal Tumor: Case Report.
Ki Nam KIM ; Ki Nam LEE ; Myong Jin KANG ; Mee Sook ROH ; Pil Jo CHOI ; Doo Kyung YANG
Korean Journal of Radiology 2006;7(1):73-76
Castleman disease is a relatively rare disorder of lymphoid tissue that involves the gastrointestinal tract in a variety of clinical and pathologic manifestations. A submucosal location has never been described in the medical literature. We report a case of esophageal Castleman disease involving thesubmucosal layer in a 62-year-old man, which was confirmed on pathology. Esophagography and CT demonstrated an intramural tumor, and a leiomyoma or leiomyosarcoma was suspected based on the known incidence of such tumors.
Mucous Membrane/*pathology
;
Middle Aged
;
Male
;
Humans
;
Giant Lymph Node Hyperplasia/*diagnosis
;
Esophageal Diseases/*diagnosis
;
Endoscopy
;
Diagnosis, Differential
10.Pelvic Castleman's disease presenting as an adnexal tumor in a young woman.
Jisun LEE ; Jiheum PAEK ; Yong Hee LEE ; Tae Wook KONG ; Suk Joon CHANG ; Hee Sug RYU
Obstetrics & Gynecology Science 2015;58(4):323-326
Castleman's disease (CD) is a rare benign disorder of unknown etiology characterized by proliferation of lymphoid tissues. Seventy percent of this tumor occurs in the mediastinum and it is seldom found in neck, pancreas or pelvis. We report a case of asymptomatic pelvic CD initially presenting as an adnexal tumor in a 27-year-old woman. Initial transvaginal sonography revealed 7-cm-sized hyperechoic mass adjacent to the right ovary and the following abdominal computed tomography scanning showed the same sized mass located on the right extraperitoneal pelvic cavity. Laparoscopic mass excision was performed without any complication and pathological diagnosis was made as CD. CD should be included in the differential diagnosis of female pelvic masses which are noted in the pelvic cavity. In this report, we review the clinicopathological findings in a presentation of CD.
Adult
;
Diagnosis
;
Diagnosis, Differential
;
Female
;
Giant Lymph Node Hyperplasia*
;
Humans
;
Lymphoid Tissue
;
Mediastinum
;
Neck
;
Ovary
;
Pancreas
;
Pelvis