A comparative investigation on the effect of ampicillin and procaine penicillin in the treatment of uncomplicated male gonorrhoea is presented. Three hundred and twenty eight male patients with uncomplicated gonococcal urethritis at a Venereal Disease Center in Seoul was subjected to this study. 164 patients were treated with 3.5 gm ampicillin plus l.0 gm probenecid, and 87 patients were followed. There were 16 (18.4%) failures and 15(21.1%) postgonococcal erethritis(PGU). Other 164 patients were treated with 4.8 million units produced penicillin plus 1.0gm prohenecid, and 73 patients were followed. There were 11 (15.1%) failures and 11(17.7%)PGU. There was no statistically significant difference of effect in the treatment of gonorrhoea between above two drugs. It is suggested that ampicillin plus probenecid is as effective as procaine penicilIin plus probenecid in the treatment of uncomplicated male gonococca1 urethritis.
Male ; Humans

OBJECTIVE: The study of 467 cases of amniocentesis have been done at the department of Genetics, Taegu Cheil Hospital from Oct. 1997 to May 1999 for the purpose of analysis of abnormal karyotype according to the indication and age distribution, METHODS: We collected amniotic fluid using 22G spinal needle and measured amniotic alphafetoprotein and acetylcholine esterase in supematant and performed cytogenetic analysis. RESULTS: Positive Down screeing(positive triple test) was the most common indication of amniocentesis (61.5%) and abnormal karyotypes were 24 cases(5.1%) in 467 cases. Among 24 abnormal cases, 10 cases(2.1%) of 21 trisomy were observed. Abnormal karyotypes were most common in the group of abnormal ultrasonogram finding and the gmup of maternal age between 31 to 35 years old, which consists of 25% and 7.7% respectively. CONCLUSION: More attention for the abnormal karyotype should be paid to the group of abnormal ultrasonogram finding and the group of maternal age between 31 to 35 years old as well as above 35 years old.
Abnormal Karyotype ; Acetylcholine ; Adult ; Age Distribution ; Amniocentesis ; Amniotic Fluid ; Cytogenetic Analysis* ; Cytogenetics* ; Daegu ; Female ; Genetics ; Humans ; Karyotype ; Maternal Age ; Needles ; Trisomy ; Ultrasonography

The recent discovery of plasmid derived beta-lactamase production by N. gonorrhoeae has changed the outlook of treatment of gonococcal infections and may well become the single most important factor in gonorrhoea control. Penicillinase is a beta-lactamase that splits the beta-lactam ring of penicillin hetween the C and N atoms to form penicilloic acids. We have been trying to assess the prevalence of PPNG in Korea since May 1980. We report here 7 strains of beta-lactamase producing N. gonorrhoae detected by chrornogenic cephalosporin method from Jan. 1981 to Mar. 1981 at the Joong Ku puhlic health center in Seoul. In January, I strain (l.3%); February, 2 strains (5.0%); and March, 4 strains .(6 4%) have been isolated. All restrains were confirmed by sugar feriventation test. Previously only one strain of PPNG had been reported among Korean laymen. The sudden appearance of PPNG among Korean laymen in 1981 may mean the barruer between U.S. Army enc1aves and Korean public has been broken recently and/or direct irnport of PPNG frorn abroad especially from South East Asia.

The idiopathic calcinosis of the scrotum (Shapiro, 1970) is usually multiple, asymtomatic nodules of the scrotal skin which begins m childhood or early adult life, increase in the size and numbers, and sometimes breakdown to discharge chalky contents. Clinically they are most often misdiagnosed as cysts. The forty eight years old male patient visited our hospital on Oct. 14, 1980, because of multiple asymtomatic scrotal masses which are pin head to walnut sized. There is no family history of calcification, scrotal or otherwise. Histology shows naked amorphous masses in the dermis without any evidence of residual cysts, and is acicular clefts in the masses. Most of the tumors were surgically removed in 5 sessions.
Adult ; Calcinosis* ; Dermis ; Head ; Humans ; Juglans ; Male ; Scrotum* ; Skin

No abstract available.
Idiopathic Pulmonary Fibrosis* ; Radiographic Image Enhancement*

Lichen sclerosus et atrophicus (LSA) is an uncommon condition of the skin with small white macular or atrophic plaques which predominantly affects the genital regions of middle aged and elderly women. We present an atypical case of LSA on a 58 year old woman. The patient had a brownish-black colored patch of 2.5 * 7.0 cm in size on the right clavicular area of one year's duration. The histopatholgy of the lesion disclosed classical findings of LSA. A marked incontinence of pigment is noted in the upper dermis which accounts for the clinical picture of the lesion. She was treated with topical hydrocortisone cream resulting in a marked diminution of pigmentation.
Aged ; Dermis ; Female ; Humans ; Hydrocortisone ; Lichen Sclerosus et Atrophicus* ; Lichens* ; Middle Aged ; Pigmentation ; Skin

The lesions of central nervous system in tuberous sclerosis often calcify, especially those present in the perivascular region, allowing the computed tomography to make early and definite diagnosis, even when patients intelligence was normal, seizures were absent, or clinical findings were not specific, We report three cases of tuberous sclerosis, which showed pathognomic subependymal paraventricular calcification in brain CT.
Brain* ; Central Nervous System ; Diagnosis ; Humans ; Intelligence ; Seizures ; Tuberous Sclerosis*

Suture microvascular anastomosis is time-consuming and tedious and demands long and continuous training. The Unilink instrument system is a fast and simple method to achieve high patency rates without long and continuous training in the anastomosis of small vessels. The author experimentally studied the carotid arteries and facial veins of 14 rabbits with an average weight of 1900 gm using the unilink apparatus. A total of 27 arterial and venous anastomoses were performed. We examined the postoperative patency at immediate, 2 weeks, and 8 weeks. The results were as followings; 1. All anastomosed vessels were fully patent just after operation and at 2 weeks(100%), but one of the arterial anastomosis was thrombotized at 8 weeks(90%) 2. The mean time for completion of the anastomosis were 8.5 minutes(range 6-15) in arteries and 6.2 minutes.(range 4-10) in veins. 3. The cases having partial obliterations were 3 cases(15%) under the operating microscope. 4. At the histological examination, the thickness of vessel wall was decreased due to moderate atrophy of the media and mild degree of nonspecific chronic inflammation was seen around the unilink apparatus. 5. A case of the arterial anastomosis was released with acting out at 15 minutes after operation, and a case of arterial anastomosis showed complete oblieration at postoperative 8 weeks. 6. The important factors in the technical problems were the proper selection of the ring size and optimal fitting between two rings. The Unilink method provides a very safe, fast, and simple way to perform microvascular anastomoses.
Acting Out ; Arteries ; Atrophy ; Carotid Arteries ; Inflammation ; Methods ; Rabbits ; Sutures ; Veins

Agressive osteoblastoma is a very rare primary bone tumor having locally aggressive and destructive natures.But distant metastasis is not well occurred. Aggressive osteoblastoma may be similar to osteoblastomaradiologically, but has different pathological featurs. We experienced one case of aggressive osteoblastomaarising from left ilium and report this case with review of the literatures.
Ilium ; Neoplasm Metastasis ; Osteoblastoma

A clinical analysis and follow-up study were performed with 35 cases of subarachnoid hemorrhage of unknown etiology among 217 cases of spontaneous subarachnoid hemorrhage who were diagnosed by cerebral pan-angiohraphy and brain C-T scan and treated at department of neurosurgery, Chonju Presbyterian Medical Center from 1977 to 1982. The duration of follow-up study was 6 months to 8 years(mean 4.4years). The author obtained the following results. 1) Subarachnoid hemorrhage of unknown etiology was 16% of 217 cases of spontaneous hemorrhage. 2) The incidence of subarachnoid hemorrhage of unknown etiology was high in 5th decade and higher in women. 3) Manifestations of subarachnoid hemorrhage of unknown etiology were similar to those of ruptured aneurysm. 4) When primary cerebral pan-angiography was normal, the secondary cerebral pan-angiography was not so meaningful. 5) The overall prognosis of the cases of unknown etiology was good in 30 among 35 cases(86%) who were able to return to their previous occupation. 6) Age and blood pressure were probably major prognostic factor.
Aneurysm, Ruptured ; Blood Pressure ; Brain ; Female ; Follow-Up Studies ; Hemorrhage ; Humans ; Incidence ; Jeollabuk-do ; Neurosurgery ; Occupations ; Prognosis* ; Protestantism ; Subarachnoid Hemorrhage*