Among the patients visting Department of Dermatology, Chungman National University, 58 cases had various side effects due to the malpractice of skin disorders. We analysed these 58 cases and the results can be summerized as follows ; 1. 37 cases(64%) were in the second and third decades and 11 cases(19%) were under 19 years-old. 2. Drug medication from pharmacy was the most common(79%), and then local clinics(12%), herb clinics(9%) in decreasing orders. 3. In the route of administration, oral ingestion(38%) was the most common, and 47 cases (81%) were medicated with adrenocorticoids. 4. In motivation to the visit, 31 cases(53%)were by advice, 15 cases by advertizement and 12 cases (21%) by themselves. 5. Acne and psoriasis were about a half of pre-existing skin diseases. 6. Side effects due to malpractice may be divided into 5 items : systemic side effects due to adrenocorticoids (59%), aggravation of pre-existing skin diseases (22%), topical side effects due to adrenocorticoids (10%), chemical irritation and burn (7%), and mercury intoxication (2%) in decreasing orders.
Acne Vulgaris ; Administration, Oral ; Burns ; Dermatology ; Humans ; Malpractice* ; Motivation ; Pharmacy ; Psoriasis ; Skin Diseases* ; Skin* ; Young Adult

This 22-year-old female patient has had a lozenge shaped hair tuft with terminal hair on the lumbosacral area since birth. A limping gait due to discrepancy of the length of the lower extremities has also been noted since 5 year age. Subsequently multiple, recurrent trophic ulceration developed on the left foot because of sensory loss. Simple cervico-lumbar spine x-ray showed spina bifida occulta of L-2 to sacrum. Lumbar myelography revealed widened vertebral canal without other spinal anomaliea.
Female ; Foot ; Gait ; Hair ; Humans ; Lower Extremity ; Myelography ; Nevus* ; Parturition ; Sacrum ; Spina Bifida Occulta* ; Spinal Dysraphism* ; Spine ; Ulcer ; Young Adult

We report a case of Hunter's syndrome in an 8-year-old boy, who presented with ivory-white colored papules and ridges on the left chest area, which were regarded as pathognomonic cutaneous markers for Hunter's syndrome. He also showed growth retardation, dear corneas, hepatosplenomegaly and fair intellect. The histopathological findings of papular lesions revealed loosely arranged collagen fibers with massive mutinous material which stained positively with alcian blue at both pH 2.0 and 0.5. On quantitation of glycosaminoglycans by hexuronic add assay in 24-hour urine, excessive excretion of creatinine was noted. To the best of our knowledge, this is the first case in Korea.
Alcian Blue ; Child ; Collagen ; Cornea ; Creatinine ; Glycosaminoglycans ; Humans ; Hydrogen-Ion Concentration ; Korea ; Male ; Mucopolysaccharidosis II* ; Thorax

We report two cases of midline granuloma of the face which occurred in 60-year-old man and 28-year old man. The former who wa.s suffered from nasal stuffness on the right nasal cavity for 10 months had yellow-brownish colored crusted erythema tous plaque on the right naris. The latter had painful erythematous swelling on the left lower eyelid and ulceration on the hard palate. Both shows polyrnorphous infiltration of atypical mononuclear cells with an admixture of normal inflammatory cells histopathologically.
Adult ; Erythema ; Eyelids ; Granuloma* ; Humans ; Middle Aged ; Nasal Cavity ; Palate, Hard ; Ulcer

We report two cases of murine typhus diagnosed by indirect immunofluorescent test. The patients showed cardinal symptoms and signs such as fever and chill, general myalgia, intractable headache and typical rash. Laboratory values and histopathologic findings were compatible with murine typhus. The oral administration of doxycycline improved dramatically the clinical manifestations of the two CCLSPS.
Administration, Oral ; Doxycycline ; Exanthema ; Fever ; Headache Disorders ; Humans ; Myalgia ; Typhus, Endemic Flea-Borne*

We report a case of staphylococcal septicemia with skin lesions characteristic of septic emboli in a 55-year-old man. Examination of the skin revealed small pustules surrounded by wide ring of erythema on the trunk and extremities. Histopathologic examination of a pustule showed subcorneal pustule and Gram positive septic emboli within blood vessels. There were neutrophilic infiltration and numerous extravasated erythrocytes within dermis. Staphylococcus aureus was isolated on the bacterial culture of blood and small pustules, He was treated with cloxacillin, but died due to respiratory distress syndrome.
Blood Vessels ; Cloxacillin ; Dermis ; Erythema ; Erythrocytes ; Extremities ; Humans ; Middle Aged ; Neutrophils ; Sepsis* ; Skin* ; Staphylococcus aureus

No abstract available.
Blood Pressure* ; Extremities*

BACKGROUND: Electronic bulletin board systems have been used for education, information exchange, and medical consultation for a number of years. However, most of these systems have been text-based. The field of dermatology has never had a system that allowed a quick exchange of visual information. OBJECTIVE: Dermatology is a field of medicine which especially requires a visual image for an accurate diagnosis, and subsequent effective treatment. We have developed a web-based bulletin board system which can be used by any clinician with access to the internet to view clinical images of skin diseases with accompanying clinical findings. METHODS: A web-based bulletin board system was developed for the internet. The system is designed to operate independently of client hardware and software using hyper text markup language so participants using different platforms can access and use the site effectively. RESULTS: Any participant can easily upload a diagnostic image to the board along with relevant clinical information. Other participants can make comments regarding the presented case which may prove useful to the presenter in diagnosis and development of an effective treatment modality. CONCLUSION: Our web-based bulletin board system for discussion of skin diseases has the potential to help in the diagnosis and treatment of various skin diseases. Dissemination of information relating to clinical cases and participation of a widespread audience of experienced clinicians will allow better practice of dermatology and aid in further training of inexperienced clinicians.
Dermatology ; Diagnosis ; Education ; Internet ; Skin Diseases* ; Skin*

BACKGROUND: Nosocomial urinary tract infection (UTI) accounts for 35% of the nosocomial infection and 80-90% of them are associated with urethral catheters. Recently, we experienced an outbreak of nosocomial UTI caused by multidrug-resistant Pseudomonas aeruginosa in neurosurgical intensive care unit (NSICU). METHODS: We investigated clinical records of the patients and observed the methods of care of urethral catheters in NSICU. Identification of P. aeruginose was done by API NE (API system; bioMerieux, France) and antibiotic susceptibility tests were done by disk diffusion method. Random Amplification of Polymorphic DNA (RAPD) assay was used as a genotyping method. RESULTS: Between November 1997 and January 1998, 11 P. aeruginosa strains were isolated from the urine of 11 patients hospitalized in NSICU of Kangnam St. Mary's Hospital. Routine regular bladder irrigation, and emptying urine with common urinal had been done falsely. Antibiogram of the isolates showed resistance to multiple antibiotics including imipenem, gentamicin. amikacin, piperacillin, ciprofloxacin, ceftazidime, and cefoperazone/sulbactam. RAPD of the outbreak strains showed clonal relatedness, which was different from those of other clinical strains, We instructed all the health care workers to stop bladder Irrigation, and to use the separate urinals for each patient. Thereafter, no further case of P. aeruginosa UTI has occurred. CONCLUSION: An outbreak of UTI, caused by a single clone of P. aeruginosa, was confirmed by RAPD and was eradicated after correction of false practice on care-of urinary catheter.
Amikacin ; Anti-Bacterial Agents ; Ceftazidime ; Ciprofloxacin ; Clone Cells ; Cross Infection ; Delivery of Health Care ; Diffusion ; DNA ; Drug Resistance, Multiple ; Gentamicins ; Humans ; Imipenem ; Intensive Care Units ; Microbial Sensitivity Tests ; Piperacillin ; Pseudomonas aeruginosa* ; Pseudomonas* ; Urinary Bladder ; Urinary Catheters ; Urinary Tract Infections* ; Urinary Tract*