1.Placental Site Trophoblastic Tumor(PSTT) with Vaginal Metastasis: A case report.
Yee Jeong KIM ; Kyu Rae KIM ; Soon Hee JEONG ; Ho Geun KIM ; Jang Yeon KWON
Korean Journal of Pathology 1991;25(6):570-575
PSTT has been established as a separate entity distinct from choriocarcinoma since 1983, because of its different morphological features, biologic behavior and response to chemotherapy. Most cases of PSTT have indolent clinical courses, but there have been several reports showing malignant behavior resulted in death of the patient. We report a case of PSTT showing vaginal metastatis. In biopsy specimen, it was difficult to make differential diagnosis from squamous cell carcinoma of uterine cervix due to uniform and mononuclear cytologic characteristics. Immunohistochemical stains for hPL and hCG were not typical for either PSTT or choriocarcinoma. We suggest that poorly differentiated PSTT may synthesize the lesser amount of hPL than typical PSTT and it may behave more aggressively.
Diagnosis, Differential
;
Biopsy
2.Four Cases of Steroid-Induced Lipodystrophy.
Youn Hee KIM ; Geun Mo KIM ; Young yun CHOI ; Tai Ju HWANG
Journal of the Korean Pediatric Society 1995;38(6):843-847
No abstract available.
Lipodystrophy*
3.A Case of Acute Megakaryoblastic Leukemia in Infant with Down's Syndrome.
Jung Soon WHANG ; Soon hee KIM ; Moon Ja KIM ; Keun LEE ; Je Geun CHI
Journal of the Korean Pediatric Society 1988;31(8):1064-1070
No abstract available.
Down Syndrome*
;
Humans
;
Infant*
;
Leukemia, Megakaryoblastic, Acute*
4.MR imaging in Moyamoya disease: utility of partial flip angle T2- weighted spin-echo imaging.
Kee Hyun CHANG ; Moon Hee HAN ; Jeong Geun YI ; In One KIM ; Man Chung HAN
Journal of the Korean Radiological Society 1991;27(4):479-484
No abstract available.
Magnetic Resonance Imaging*
;
Moyamoya Disease*
5.A case of Kugelberg-Welander syndrome.
Sun Young LEE ; Myung Ik LEE ; Soo Wha KIM ; Don Hee AHN ; Je Geun CHI
Journal of the Korean Pediatric Society 1992;35(9):1263-1266
No abstract available.
Spinal Muscular Atrophies of Childhood*
6.A Study on the CD34 Expression of Cutaneous Benign and Malignant Vascular Tumors.
Yong Kwan BAIK ; Hyung Geun MIN ; Ho Gyun LEE ; Jong Min KIM ; Jin Hee SOHN
Korean Journal of Dermatology 1998;36(5):759-764
BACKGROUND: CD34 is a 115 kD glycoprotein which is expressed on hematopoietic progenitor cells. It is also known as an immunohistochemical marker of endothelial cells. OBJECTIVE: This study was designed to investigate the patterns of CD34 expression on: (1) cutaneous benign and malignant vascular tumors and (2) on the mature and immature vessels of pyogenic grauloma and capillary hemangioma. METHOD: We performed immunoperoxidase staining using a monoclonal anti-CD34 antibody (QBEND/10) on formalin fixed, paraffin-embedded sections of 23 benign and malignant cutaneous vascular tumors. RESULTS: The results are summerized as follows: 1. In 3 cases of nevus flammeus and 6 cases of carvernous hemangioma, vascular endothelial cells of all hemangiomas showed CD34 expressions. In 5 cases of angiokeratoma, endothelial cells of hemangioma, did not express CD34. 2. In all 5 cases of pyogenic granulomas and one case of capillary hemangioma, endothelial cells of mature vessels, endothelial cells near the well-formed lumina and endothelial cells showing intracellular lumina showed strong positivity for CD34, wbile endothelial cells far from the lumina and endothelial cells without lumina formation mostly showed negative staining for CD34. 3. One cese of Kaposis sarcoma showed focall positivity for CD34 both in endothelial cells of the small, well-formed vessels and spindle cells. Two cases of angiosarcoma showed CD34 expression only in endothelial cells of well-formed, normal appearing vessels, whereas atypical endothelial cells of tumor vessels and spindle cells were negative for CD34. CONCLUSION: CD34 could be a marker for endothelium in mature, well-differentiated vascular structures and may serve as a marker of lumen formation or differentiation of endothelial cells.
Angiokeratoma
;
Endothelial Cells
;
Endothelium
;
Formaldehyde
;
Glycoproteins
;
Granuloma, Pyogenic
;
Hemangioma
;
Hemangioma, Capillary
;
Hemangiosarcoma
;
Hematopoietic Stem Cells
;
Negative Staining
;
Port-Wine Stain
;
Sarcoma, Kaposi
7.Achondrogenesis Type 2: An autopsy case.
Joon Mee KIM ; Young Chae CHU ; Soo Kee MIN ; Hee Jeung CHA ; Je Geun CHI
Korean Journal of Pathology 1997;31(5):482-488
Achondrogenesis type 2 is a lethal form of congenital skeletal dysplasia characterized by severe short-limbed dwarfism, decreased vertebral ossification and normal ossification of the skull. We report an autopsy case of achondrogenesis type 2 in a female fetus terminated at 29 weeks of gestation. External morphology revealed a relatively large head, short upper and lower extremities, short neck, and distended abdomen. The x-ray finding showed normal calvarial ossification, hypoplastic ilium and unossified ischium, and metaphyseal flares of the femur and tibia. Histologically, chondrocytes were large and irregular with increased vascularity.
Abdomen
;
Autopsy*
;
Chondrocytes
;
Dwarfism
;
Female
;
Femur
;
Fetus
;
Head
;
Humans
;
Ilium
;
Ischium
;
Lower Extremity
;
Neck
;
Pregnancy
;
Skull
;
Tibia
8.A Case of Contact Dermatitis due to Herb Ointment.
Dong Geun KANG ; Kwang Soo KIM ; Hee Jin CHO ; Kyu Joong AHN ; Cheol Heon LEE
Korean Journal of Dermatology 1990;28(2):212-215
A case of contact dermatitis due to herb onintment is described in a 24 year-old female patient. After topical application of herb ointment, she developed erythematous papules and plaques on the face and neck. Patch test revealed positive reactions to ammoniated mercury, thimerosal, and the herb ointment. Energy-dispersive X-ray microanalysis of the herb ointment showed a striking peak for mercury.
Dermatitis, Contact*
;
Electron Probe Microanalysis
;
Female
;
Humans
;
Neck
;
Patch Tests
;
Strikes, Employee
;
Thimerosal
;
Young Adult
9.Congenital Systemic Cytomegalic Inclusion Disease.
Dong Beom LEE ; Dong Hyun KIM ; Jung Sik MIN ; Chang Hee CHOI ; Je Geun CHI
Journal of the Korean Pediatric Society 1990;33(1):100-106
No abstract available.
Cytomegalovirus Infections*
10.A Case of Steven-Johnson Syndroe Associated with Cholestatic Hepatitis.
Tae Hee PARK ; Ran Ju KIM ; Byoung Geun LEE ; Soo Chul CHO ; Dae Yeol LEE
Journal of the Korean Pediatric Society 1994;37(7):1016-1019
A 12-year-old boy developed cholestatic hepatitis with Steven-Johnson syndrome following the use of amoxicillin. The skin lesion and general condition were improved over 2 weeks, but jaundice was gradually aggrevated. We performed liver biopsy, on 30th hospital day, which showed cholestatic hepatitis. The patient improved gradually and liver function was normalized 5 months later.
Amoxicillin
;
Biopsy
;
Child
;
Hepatitis*
;
Humans
;
Jaundice
;
Liver
;
Male
;
Skin