Solitary plasmacytoma of bone, one form of plasma cell neoplasms, is relatively rare. We successfully treated two cases of solitary plasmacytoma of the spine. Both patients underwent surgery. In a 46-year-old female, the tumor of C7 vertebral body was removed completely and the patient received postoperative radiotherapy(5400 rad). After a follow-up period of 27 months, she had no local recurrence. In the other 42-yea-old male, the tumor of the T6 vertebral body was partially removed and the patient did not receive postoperative radiotherapy. After 20 months, the patient had local recurrence with serious neurological deficits(paraparesis). We removed the regrown tumor mass totally, and his symptoms and signs were improved clinically. Then he received radiotherapy(5000 rad). After the mean follow up period of 33 months, neither patient developed disseminated systemic myeloma. The outcome of solitary osseous plasmacytoma is relatively good with surgically excision followed by local irradiation. Close long term follow-up of solitary plasmacytoma of bone is needed to detect progression to multiple myeloma. We report two cases of solitary plasmacytome of bone with a brief review of the literature.
Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Multiple Myeloma ; Neoplasms, Plasma Cell ; Plasmacytoma ; Radiotherapy ; Recurrence ; Spine*