The study on three varieties of Geranium nepalense Kudo cultivated in Ha Noi Herbal Research Center in the 2001-2002 crop showed that: the average growth time of median-term variety is 190 days. This variety has most vigorous growth with highest height and largest volume, produce highest herbal productivity. This variety is more likely to be suitable to land and climate conditions of Red River delta. The content of essential substance such as tanin and flavonoid of varieties II and III is comparable
Geranium ; Plants, Medicinal ; Evaluation Studies

PURPOSE: The purpose of this study was to investigate the effects of aromatherapy on the level of anxiety and fatigue in student nurses who were undergoing their first clinical practice. METHOD: A non-equivalent, control group, pretest-posttest design was used. A convenience sample of 42 student nurses were selected. They were assigned to experimental and control groups. The aromatherapy using lavender, geranium and camomile was given to the experimental group for four consecutive days while the control group only rested. RESULT: 1.Anxiety scores for the experimental group were significantly lower than those of the control group on the 2nd, 3rd and 4th days of clinical practice. 2. Fatigue scores for the experimental group were significantly lower than those of the control group on the 2nd, 3rd and 4th day of clinical practice. CONCLUSION: The results support the conclusion that aromatherapy using selected essential oils is an effective intervention for relieving anxiety and fatigue in student nurses experiencing their first clinical practice. However differences between aromatherapy and massage were not clear. Further investigation needs to be done.
Anxiety* ; Aromatherapy* ; Chamomile ; Fatigue* ; Geranium ; Humans ; Lavandula ; Massage ; Oils, Volatile

PURPOSE: This study was to examine the effects of aroma hand massage on pruritus, fatigue and stress of the patients undergoing hemodialysis. METHODS: This study was a nonequivalent control group pretest-posttest design. Study sample was conveniently recruited from two hospitals(28 for experimental and 30 for control group). The experimental group went through aroma hand massage on hand without AVF for 5 min for 12 times mixed with Lavender, Chamomile and Geranium oils in the ratio of 4 : 4 : 2, which was diluted 3% with sweet almond crrier oil 100 ml. The collected data were analyzed using SPSS/WIN 12.0. RESULTS: The 1st hypothesis, 'Experimental group who has received aroma hand massage will have lower rate of pruritus than the control group' was accepted(t = -5.084, p = .001). The 2nd hypothesis, 'Experimental group who has received aroma hand massage will have lower rate of fatigue than the control group' was accepted(t = -2.557, p = .015). The 3rd hypothesis, 'Experimental group who has received aroma hand massage will have lower rate of stress than the control group' was accepted(t = -5.537, p = .001). CONCLUSION: The aroma hand massage has shown to be an effective nursing intervention to reduce the pruritus, fatigue and stress among patients undergoing hemodialysis. Therefore, the massage is needed to continuously be applied to hemodialysis patients to improve their quality of life.
Aromatherapy ; Chamomile ; Fatigue ; Geranium ; Hand ; Humans ; Lavandula ; Massage ; Oils ; Prunus dulcis ; Pruritus ; Renal Dialysis

Necrotic enteritis (NE) caused by Clostridium (C.) perfringens commonly occurs in domestic broiler farms since antibiotic supplementation in poultry feed has been banned. We evaluated the antibacterial activities of medicinal plant extracts against C. perfringens isolates to select alternative compounds for preventing NE. We compared antibacterial activities using two methods and evaluated susceptibilities of the isolates based on minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Two (Fraxinus rhynchophylla Hance [FRH] and Geranium koreanum Kom. [GKK]) of the 30 plant extracts had potent antibacterial activities against C. perfringens ATCC 13124 in two assays. The MIC values for FRH and GKK against 20 C. perfringens isolates were 128~256 microg/mL and 32~128 microg/mL, respectively. The geometric MIC mean values for the two extracts were 147.2 microg/mL and 68.8 microg/mL, respectively. The MBCs for the two extracts against the same strains were 1,024~2,048 microg/mL and 256~1,024 microg/mL, respectively. The geometric mean MIC and MBC for GKK were about two-fold lower than those of FRH. The modified spot-on-lawn assay may be useful for measuring primary antibacterial potential. FRH and GKK are expected to be used as feed additives to prevent or treat NE in veterinary practice.
Chickens* ; Clostridium ; Clostridium perfringens* ; Enteritis ; Fraxinus* ; Geranium* ; Microbial Sensitivity Tests ; Plant Extracts ; Plants, Medicinal ; Poultry

In order to optimize extraction process conditions of tannins from Geranium orientali-tibeticum by supercritical CO2, the content of tannins was determined by phosphomolybdium tungsten acid-casein reaction, with extraction pressure, extraction temper- ature and extraction time as factors, the content of tannins from extract of G. orientali-tibeticum as index, technology conditions were optimized by orthogonal test. Optimum technology conditions were as follows: extraction pressure was 25 MPa, extraction temperature was 50 °C, extracted 1.5 h. The content of tannins in extract was 12.91 mg x g(-1), extract rate was 3.67%. The method established could be used for assay the contents of tannin in G. orientali-tibeticum. The circulated extraction was an effective extraction process that was stable and feasible, and that provides a way of the extraction process conditions of tannin from G. orientali-tibeticum.
Carbon Dioxide ; chemistry ; Chemical Fractionation ; methods ; Drugs, Chinese Herbal ; chemistry ; Geranium ; chemistry ; Tannins ; isolation & purification

OBJECTIVES: The aim of the present systematic review and meta-analysis is the exploration of the potential evidence of the effectiveness of aromatherapy products on the sexual function of menopausal women. METHODS: From inception to December 2017, the search process was performed using the MEDLINE and Scopus databases and the Cochrane Library regarding the trials on the effectiveness of herbal-medicine aromatherapy on the sexual function of menopausal women. RESULTS: Three of the trials comprise suitable data for inclusion in the meta-analysis. According to the meta-analysis, it is possible to improve the standardized mean difference (SMD) of the sexual desire up to 0.56 in the aromatherapy group compared with the control group (SMD = 0.56; P < 0.001; heterogeneity; I² = 42%; P = 0.141). According to one of the trials, the serum-estrogen level of two different doses did not change in the neroli oil inhalation group compared with the almond-oil group. CONCLUSIONS: Both aromatherapy with neroli oil or lavender (monopreparation) and combined-oil aromatherapy with lavender, fennel, geranium, and rose significantly improved human sexual function; however, a significant change of the serum-estrogen level was not detected. The findings of the present review should be presented cautiously because of the corresponding limitations such as the lack of a standardized tool, the lack of intention-to-treat reporting, the low study amount, and the short-term follow-up.
Aromatherapy ; Female ; Foeniculum ; Follow-Up Studies ; Geranium ; Humans ; Inhalation ; Lavandula ; Menopause ; Population Characteristics ; Sexuality

PURPOSE: To determine the effects of 10% lidocaine spray and aroma hand massage on pain, anxiety, blood pressure, and pulse during arteriovenous (AV) fistula needling in hemodialysis (HD) patients. METHODS: This study used a quasi-experimental design. Forty HD patients were assigned to either 10% lidocaine spray group (n=21) or aroma massage group (n=19). 10% lidocaine was sprayed 3 times around AV fistula 10 minutes before. Aroma hand massage was performed for 5 minutes with fluids containing 2% of lavender, peppermint, and geranium concentrate mixture. Pain, anxiety, blood pressure, and pulse were measured during AV fistula needling without any intervention on the first week and during interventions on the second week. Data were analyzed with χ² test, Fisher's exact test, t-test, paired t-test and MANCOVA. RESULTS: Pain and anxiety were significantly decreased in both the lidocaine spray group and aroma massage group. Aroma hand massage was more effective to reduce pulse during AV fistula needling. CONCLUSION: The results suggest that 10% lidocaine spray and aroma hand massage may be effective to reduce pain, anxiety, and pulse during AV fistula needling in HD patients.
Anxiety* ; Arteriovenous Fistula* ; Blood Pressure* ; Fistula ; Geranium ; Hand* ; Humans ; Lavandula ; Lidocaine* ; Massage* ; Mentha piperita ; Renal Dialysis*

OBJECTIVE: To relieve stress and pain during labor is most important issue in obstetrical care. The purposes of this study were to verify the effects of aromatherapy on labor process, labor pain, labor stress response and neonatal status of primipara. METHODS: This study was a randomized, repeated measures over time, pretest-posttest design. The subjects were forty eight primipara with single gestation, full term, uncomplicated pregnancies. As the treatment, the experimental group took an aromatherapy massage with aromatherapy oil (1.5% dilution essential oil of clary sage, geranium, jasmine, and rose) on the back at every two hours. The control group took general obstetric care. Baseline data including general and obstetric characteristics, plasma beta-endorphin, serum cortisol were obtained at the onset of labor. As resulting variables, length of labor, use of oxytocin, labor pain, use of analgesics, plasma beta-endorphin, serum cortisol, pulse rate, blood pressure, umbilical cord arterial blood pH, Apgar score were measured. Collecting Data were analyzed by t-test, x2 test, repeated measures of ANOVA with SPSS program. RESULTS: As a results, the length of decerelation phase of the experimental group was significantly shorter than the control group. No significant group effects were found, but significant time effects were found for labor pain, plasma beta-endorphin, serum cortisol, pulse rate and blood pressure. There were no significant differences in other variables between two groups. CONCLUSION: These findings indicate that aromatherapy during labor could be effective in decreasing labor length. But, any other effects of aromatherapy did not be verified.
Analgesics ; Apgar Score ; Aromatherapy* ; beta-Endorphin ; Blood Pressure ; Female ; Geranium ; Heart Rate ; Hydrocortisone ; Hydrogen-Ion Concentration ; Jasminum ; Labor Pain* ; Massage ; Oxytocin ; Plasma ; Pregnancy ; Umbilical Cord

OBJECTIVETo study the chemical constituents of Geranium eristemon.

METHODChromatography and spectral analysis were used to isolate the constituents and elucidate their structures.

RESULTFive compounds were isolated from acetone extract of the whole grass of G. eristemon, and identified as beta-sitosterol, protocatechuic acid, myricetin, kaempferol-7-O-alpha-L-arabifuranoside and kaempferol-3-O-alpha-L-arabifuranoside.

CONCLUSIONkaempferol-7-O-alpha-L-arabifuranoside and kaempferol-3-O-alpha-L-arabifuranoside were isolated from G. genus for the first time.

Arabinose ; analogs & derivatives ; chemistry ; isolation & purification ; Flavonoids ; chemistry ; isolation & purification ; Geranium ; chemistry ; Hydroxybenzoates ; chemistry ; isolation & purification ; Kaempferols ; chemistry ; isolation & purification ; Plants, Medicinal ; chemistry ; Sitosterols ; chemistry ; isolation & purification

BACKGROUND AND OBJECTIVES: Recently, obesity has become one of the major health problems in our society. To overcome this problem, keeping a balance between food intake and energy expenditure is very important. Many natural substances including essential oils have been suggested for their potential effect on reducing weight. This study was performed to evaluate whether aroma inhalation of essential oil has a role in appetite regulation and works on the central nervous system through the olfactory stimulus. MATERIALS AND METHOD: Food intake was measured after 30 minutes of treatment with essential oil in overnight fasted Sprague-Dawley rats. In the control group, saline was used instead of essential oil. Changes in pro-opiomelanocortin (POMC) and neuropeptide Y (NPY) mRNA expression levels in the hypothalamus were measured following 30 minutes of treatment with geranium essential oil using real-time polymerase chain reaction. RESULTS: Of the seven essential oils, geranium significantly decreased the amount of food intake compared to the control group. Geranium essential oil significantly increased POMC mRNA expression in the hypothalamus, but did not change the NPY mRNA expression. The increased POMC mRNA expression was reversed by treatment with xylocaine, which blocks the olfactory perception. CONCLUSION: These results suggest that geranium essential oil has anorexic effect through the activation of POMC neurons in the hypothalamus via olfactory stimulus.
Appetite Regulation ; Central Nervous System ; Diethylpropion ; Eating ; Energy Metabolism ; Geranium ; Hypothalamus ; Inhalation ; Lidocaine ; Neurons ; Neuropeptide Y ; Obesity ; Oils, Volatile ; Olfactory Perception ; Pro-Opiomelanocortin ; Rats, Sprague-Dawley ; RNA, Messenger