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Antibacterial and antifungal activities of liquid culture filtrate, water and ethanol extract (solid culture) of Stereum ostrea were evaluated against 5 bacteria and 3 plant pathogenic fungi. To determine the minimal inhibitory concentration (MIC), we studied 5~300 mg/ml concentrations against bacteria and fungi separately. The MIC was 10 mg/ml for Bacillus subtilis and 40 mg/ml for Colletotrichum gloeosporioides and Colletotrichum miyabeanus. Liquid culture filtrate was more effective against Gram positive than Gram negative bacteria, and Staphylococcus aureus was the most inhibited (20.3 mm) bacterium. Water and ethanol extracts were effective against both Gram positive and Gram negative bacteria, and water extract was better than ethanol extract. In water and ethanol extract, inhibition zones were 23.6 and 21.0 mm (S. aureus) and 26.3 and 22.3 mm (Pseudomonas aeruginosa), respectively. For plant pathogenic fungi, the highest and lowest percent inhibition of mycelial growth (PIMG) was found 82.8 and 14.4 against C. miyabeanus and Botrytis cinerea in liquid culture filtrate, respectively. In water extract, the PIMG was found to be the highest 85.2 and lowest 41.7 for C. miyabeanus and C. gloeosporioides, respectively. The inhibitory effect of ethanol extract was better against C. miyabeanus than C. gloeosporioides and B. cinerea. Among 3 samples, water extract was the best against tested pathogenic fungi. This study offers that the extracts isolated from S. ostrea contain potential compounds which inhibit the growth of both bacteria and fungi.
Agaricales* ; Bacillus subtilis ; Bacteria ; Botrytis ; Colletotrichum ; Complex Mixtures ; Ethanol ; Fungi ; Gram-Negative Bacteria ; Ostrea* ; Plants ; Staphylococcus aureus ; Water

Benign solitary osteochondroma is uncommon in the vertebra (2%). Vertebral ostoechondroma arises predominantly in the lumbar and cervical regions, and rarely in the sacrum. We describe a case of a sacral solitary senescent osteochondroma compressing the sciatic nerve, producing sciatica. The tumor was removed by posterior paramedian incision. The excised mass was cylindrical, measuring 3.5x1x1 cm in size and consisting of lamellar bone with Haversian system similar to the architecture of normal cortical bone and trabecular bone.
Haversian System ; Osteochondroma* ; Sacrum* ; Sciatic Nerve ; Sciatica* ; Spine

Ankylosing spondylitis (AS) is a chronic inflammatory disease presenting progressive spinal stiffness and sacroiliitis. Cervical spine fracture combined with AS should be treated with operation, but it is closely related with increased rates of surgical site infection, which are associated with an elevated erythrocyte sedimentation rate and elevated C-reactive protein. We report a case of delayed postoperative infection appeared in cervical paravertebral space, which was masked by laboratory findings and clinical characteristics represented in this rheumatic disease. A 53-year-old man who had medical history of AS got operation after cervical spine fracture. During hospitalization, he experienced aching pain originating from left posterior neck to shoulder, which was revealed out to be delayed postoperative infection, diagnostically obscured by elevated values of inflammatory markers. This case emphasizes detailed evaluation considering symptoms and comorbidity of the patient should be performed to apply proper management.

PURPOSE: In this study, we examined the anatomic characteristics of the distal femur and the proximal tibia to determine if there were significant differences between male and female patients. MATERIALS AND METHODS: Seventy six patients (50 of female, 26 of male) who were treated by total knee arthroplasty using ROBODOC(R), were included. The anteroposterior and mediolateral length of the distal femur and proximal tibia were checked using the ORTHODOC program. RESULTS: The mean sizes of the distal femur and proximal tibia of female knees were slightly smaller than those of male knees. Statistically significant differences were observed between the two groups (p<0.05 for all). On the other hand, the anteroposterior and mediolateral ratios of distal femur and proximal tibia revealed no differences between female and male knees (p>0.05 for all). CONCLUSION: The anteroposterior to mediolateral ratio was similar in the distal femur and proximal tibia of Korean females.
Arthroplasty ; Female ; Femur ; Hand ; Humans ; Knee ; Korea ; Male ; Tibia

Ganoderma lucidum (Fr.) Karst (Polyporaceae), belonging to basidiomycota, is one of the most famous medicinal mushrooms. This study was carried out to investigate favorable mycelial growth conditions, such as pH, temperature, growth media, carbon sources and nitrogen sources of Korean strains in G. lucidum. The most suitable temperature for the mycelial growth was obtained at 30degrees C. In general, optimal temperature range for the mycelial growth was found at 25~30degrees C. This Mushroom has a broad pH range (5~9) for its mycelial growth and mostly favorable growth was found at pH 5. Generally, Hamada, Glucose peptone, YM, Mushroom complete and Lilly media were the most suitable for the mycelial growth of G. lucidum. Among 10 different carbon sources, dextrin, galactose and fructose were best but the rest of other carbon sources also facilitated the growth of mycelia. The most suitable nitrogen sources were ammonium acetate, glycine, arginine and calcium nitrate, but to a certain extent, all of the supplemented nitrogen sources also stimulated the mycelial growth.
Acetates ; Agaricales ; Arginine ; Basidiomycota ; Calcium ; Calcium Compounds ; Carbon ; Fructose ; Galactose ; Ganoderma ; Glucose ; Glycine ; Hydrogen-Ion Concentration ; Nitrates ; Nitrogen ; Peptones ; Quaternary Ammonium Compounds ; Reishi

In order to evaluate the effects of injectable agents on the vas deferens, 11 groups of 5 rats(10 vasa deferens) had both vasa deferens injected by vasopuncture with normal saline, methylene blue, 7 water-soluble contract agents and 1 lipid-soluble contrast agent. After 8 weeks, they were compared with the control group for their histologic changes. There were no significantly deteriorating changes in water-soluble agents groups execpt two vasal obstructione resulted from infection. One partial ciliary loss was found in lipid-soluble agent group. In conclusion, vasography with water-solublt agents may be a saft and helpful procedure, which could give us meaningful informations in managing the patients.
Animals ; Contrast Media* ; Humans ; Methylene Blue ; Models, Animal* ; Rats* ; Vas Deferens*

In order to evaluate the effects of injectable agents on the vas deferens, 11 groups of 5 rats(10 vasa deferens) had both vasa deferens injected by vasopuncture with normal saline, methylene blue, 7 water-soluble contract agents and 1 lipid-soluble contrast agent. After 8 weeks, they were compared with the control group for their histologic changes. There were no significantly deteriorating changes in water-soluble agents groups execpt two vasal obstructione resulted from infection. One partial ciliary loss was found in lipid-soluble agent group. In conclusion, vasography with water-solublt agents may be a saft and helpful procedure, which could give us meaningful informations in managing the patients.
Animals ; Contrast Media* ; Humans ; Methylene Blue ; Models, Animal* ; Rats* ; Vas Deferens*

Currently in the Republic of Korea, most postmortem investigations occur within the context of a death scene investigation and are restricted to a postmortem inspection without a subsequent autopsy. In this study, we analyzed the discrepancies between the results of postmortem inspection and autopsy to investigate the limits of postmortem inspection. The conclusions about the cause and manner of death stated in the two reports were compared. A retrospective study was carried out on 6,126 autopsy cases performed in the Republic of Korea in 2015. Of these autopsy cases, 2,263 included postmortem inspection reports. The stated cause and manner of death conflicted with the autopsy report in 55.1% and 32.9% of the postmortem inspection reports, respectively. Among these conflicted reports, the cause and manner of death was undetermined in 66.6% and 70.3% of the postmortem inspection reports, respectively. Furthermore, different types of discrepancies were found between the causes and manner of death that were stated in the reports by police investigators and those by forensic pathologists. This study revealed that postmortem inspection is not sufficient in the postmortem investigation and forensic autopsies need to be performed.
Autopsy* ; Cause of Death ; Humans ; Police ; Republic of Korea ; Research Personnel ; Retrospective Studies

PURPOSE: To generate a Korean specific brain template, especially in patients with Alzheimer's disease (AD) by optimizing the voxel-based analysis. MATERIALS AND METHODS: Three-dimensional T1-weighted images were obtained from 123 subjects who were 43 cognitively normal subjects and patients with 44 mild cognitive impairment (MCI) and 36 AD. The template and the corresponding aprior maps were created by using the matched pairs approach with considering differences of age, gender and differential diagnosis (DDX). We measured several characteristics in both our and the MNI templates, including in the ventricle size. Also, the fractions of gray matter and white matter voxels normalized by the total intracranial were evaluated. RESULTS: The high resolution template and the corresponding aprior maps of gray matter, white matter (WM) and CSF were created with the voxel-size of 1 x 1 x 1 mm. Mean distance measures and the ventricle sizes differed between two templates. Our brain template had less gray matter and white matter areas than the MNI template. There were volume differences more in gray matter than in white matter. CONCLUSION: Gray matter and/or white matter integrity studies in populations of Korean elderly and patients with AD are needed to investigate with this template.
Aged ; Alzheimer Disease ; Brain ; Diagnosis, Differential ; Humans ; Mild Cognitive Impairment