BACKGROUND: Many studies have reported that high intraocular pressure (IOP), a well-known risk factor for glaucoma and especially primary open angle glaucoma, is associated with age, sex, hypertension, diabetes mellitus and obesity. We investigated the association between IOP and metabolic syndrome (MS). METHODS: We measured IOP and MS components according to the National Cholesterol Education Program Adult Treatment Panel III and the American Heart Association and the National Heart, Lung, and Blood Institute with modified guideline for waist circumference. High IOP was defined as > or =21 mmHg in one or both eyes. RESULTS: Looking at the components of MS in men, those with high blood pressure (BP) had significantly higher IOP. In regression analysis, fasting glucose, triglyceride, systolic BP and diastolic BP were positively, and age was negatively associated with IOP. In women, those with high fasting glucose and BP had significantly higher IOP. In regression analysis, diastolic BP, systolic BP, fasting glucose, body mass index and triglyceride were positively associated with left IOP while diastolic BP, fasting glucose and triglyceride were positively associated with right IOP. There were significantly increasing odds ratios for high IOP according to the number of components of MS. CONCLUSIONS: These findings suggest that MS and its components are significantly associated with IOP.
Adult ; American Heart Association ; Blood Glucose ; Blood Pressure ; Body Mass Index ; Cholesterol ; Diabetes Mellitus ; Fasting ; Female ; Glaucoma ; Glaucoma, Open-Angle ; Glucose ; Humans ; Hypertension ; Intraocular Pressure ; Male ; National Heart, Lung, and Blood Institute (U.S.) ; Obesity ; Odds Ratio ; Risk Factors ; Waist Circumference

In order to examine a way of utilizing the papers published in the field of oral &maxillofacial surgery, the subjects and the references from total 3,392 papers. ; 263 papers in the KJOMS(Journal of Korean Association of Oral &Maxillofacial Surgeons. vol. 17-21), 237 papers in the KJMPRS(Journal of Korean Academy of Maxillofacial Plastic and Reconstructive Surgery. Vol 13-17), 1,233 papers in the JJOMS (Journal of Japanese Association of Oral &Maxillofacial Surgeons. vol 37-41), 1,212 papers in the AJOMS(Journal of American Association of Oral &Maxillofacial Surgeons. vol 49-53), and 447 papers in the International JOMS(Official publication of the International association of Oral &Maxillofacial Surgeons vol 20-25) have been analyzed. The results were as follows: 1. The subjects of KJOMS and KJMPRS were composed of various 28 items. Among 15 main subjects excluding the minor subjects below 1%, there were Aquired deformity &-Reconstruction (17.4%), Jaw deformity (14.2%), Trauma (14.2%) and Malignant tumor (10.8%). 2. The main subjects of JJOMS were Malignant tumor (22.8%) and Benign tumor (20.6%), In AAOMS, Trauma (13.0%), Jaw deformity (13.0%), and malignant tumor 12.4%) were main subjects. In IJOMS Malignant tumor (16.1%), Acquired deformity &Reconstruction (13.0%), and Trauma (10.3%) were main subjects. 3. IN KJOMS and KJMPRS, Scientific and Clinical articles was 63.5% and Case reports was 36.5%. But scientific and Clinical articles was 43.4% and Case reports was 56.6% in JJOMS, 47.1% and 52.9% in AAOMS, 50.1% and 49.9% in IJOMS. 4. The number of institutes in KJOMS and KJMPRS was 46. The main 6 institute published the 57.4% of total articles. In IJOMS, Nationality of the author was composed of 42 nations. West Europe Area published 52.8% of total articles, and The dominant nation of the author were West Germeny (16.3%), U.K. (12.1%), and Japan (11.6%). 5. Authors cited 30.4 references per articles in average, but only 2.7 domestic articles was cited in KJOMS and KJMPRS. It was 17.4 references, but 9.3 domestic articles was cited. In AJOMS and IJOMS, were 19.5 and 18.0 references.
Academies and Institutes ; Asian Continental Ancestry Group* ; Congenital Abnormalities ; Ethnic Groups ; Europe ; Humans ; Japan ; Jaw ; Plastics ; Publications

No abstract available.
Hemorrhage*

No abstract available.
Hemorrhoids*

No abstract available.
Hemorrhoids*

With advance of diagnostic imaging technics, the detection rate of small hepatocellular carcinoma (HCC) has become much increased, but the questions whether the growth pattern and histologic nature of the HCC keep maintain the original gross and microscopic features with its advancement of tumor size remain still unclear. We reviewed 39 surgically resected hepatocellular carcinomas(HCCs) with a tumor size less than or equal to 3 cm in diameter(s-HCC), and their gross and microscopic features were compared with the HCCs bigger than 3 cm (i-HCC, 199 cases). Single nodular type(SN) was the most common gross type(60%) in s-HCCs, and was followed by single nodular type with perinodular extension(SNPE; 15.4%), multinodular-discrete type(10.3%) and multinodular-confluent type(5.1%). These figures contrasted to SNPE(42.2%) and SN(20.6%) in the i-HCCs. Of the 39 s-HCCs, 25 cases(64.1%) were encapsulated, and 14 cases(36%) demonstrated intratumoral fibrous septations, being contrasted to the i-HCCs in which fibrous septa formation was mord prominent but complete capsule formation was found only in 40.2% of the larger ones. Microscopically, the trabecular type was the most frequent one(53.9%), and increased with their size while the compact type transformed into trabecular one. Thirty three cases(84.6%) were associated with macronodular cirrhosis. Seropositivity for HBsAg was found in 26 cases(66.6%), and high serum alpha-fetoprotein level over 500 IU/L was found in 15 s-HCC cases(38.4%), while 53.3% in i-HCC. The above results suggest that HCCs change their pathologic features by increase of their size, and a comparison of the details with regard to the possible mechanisms involved is discussed.
Carcinoma, Hepatocellular

Potter's syndrome including bilateral renal agenesis or polycystic renal disease, bilateral pulmonary hypoplasia and characteristic face was first described in 1946. Although a great number of cases of Potter's syndrome was reported, Potter's syndrome with adult polycystic kidney disease(Potter type III) was very rarely found. In this report, we described an autopsy case of Potter's syndrome having adult polycystic kidneys disease, bilateral pulmonary hypoplasia and characteristic face in conjunction with multiple hepatic cysts, features of congenital hepatic fibrosis and a pancreatic cyst. Microscopically, all cysts were lined by cuboidal epithelial cells, showing positive for epithelial membrane antigen and cytokeratins.
Adult* ; Autopsy* ; Epithelial Cells ; Fibrosis ; Humans ; Keratins ; Mucin-1 ; Pancreatic Cyst ; Polycystic Kidney Diseases*

Interleukin 1(IL-1), a 17.5 KD glycoprotein, is known to be associated with local bone resorption. In the present study, we examined the effects of IL-1, compared with insulin and parathyroid hormone (PTH), on DNA, protein and collagen synthesis in UMR-106-01 rat osteoblastic osteosarcoma cells. When 200 units/mL IL-1 was administered to UMR-106-01 cells, [3H]-thymidine uptake increased to 119% of the untreated control. But when 10 nM insulin was added to the cells, [3H]- thymidine uptake increased to 130% and when 1 nM PTH was added, the uptake decreased to 89% of the control. On the other hand, protein and collagen synthesis, measured by [3H]-leucine and [3H]-proline incorporation respectively, were not affected by IL-1 administration compared to the other hormones. These results indicate that IL-1 effects osteoblast-like cells, stimulating DNA synthesis via a different mechanism to the well-known cell growth factor, insulin.
Animals ; Bone Resorption ; Cell Proliferation* ; Collagen ; DNA ; Glycoproteins ; Hand ; Insulin ; Interleukin-1* ; Interleukins ; Osteoblasts ; Osteosarcoma ; Parathyroid Hormone ; Rats ; Thymidine

No abstract available.

No abstract available.
Cleft Lip ; Humans ; Orthognathic Surgery ; Palate