1.Chronic Hemorrhagic Radiation Proctitis Treated by Sucralfate Enema.
Geom Seog SEO ; Suck Chei CHOI
The Korean Journal of Gastroenterology 2006;47(5):335-336
No abstract availble.
Aged
;
Chronic Disease
;
Colonoscopy
;
*Enema
;
Female
;
Humans
;
Proctitis/*drug therapy/pathology
;
Radiation Injuries/*drug therapy/pathology
;
Sucralfate/*administration & dosage
2.Pathophysiology of ulcerative colitis - Relationship with genetics and immunity.
Geom Seog SEO ; Suck Chei CHOI
Korean Journal of Medicine 2009;76(6):643-648
The current paradigm holds that ulcerative colitis occurs in genetically predisposed individuals because of dysregulated immune responses against intraluminal bacterial antigens. Recently, numerous new genes have been identified as involved in the genetic susceptibility to ulcerative colitis, including IL-23R, MST1, IL-12B (p40), NKX2-3, and STAT3. Experimental studies of ulcerative colitis point to an excessive T-cell response to antigenic stimulus resulting in damage to host intestinal tissue. The T-cell response in ulcerative colitis appears to be TH2 dominant (IL-5, IL-13) and mediated by specialized cells, such as NK T-cells. The characterization of these novel genes and immunologic basis should lead to the identification of therapeutic agents and a better clinical assessment of phenotype and prognosis in patients with ulcerative colitis.
Antigens, Bacterial
;
Colitis, Ulcerative
;
Genetic Predisposition to Disease
;
Humans
;
Phenotype
;
Prognosis
;
T-Lymphocytes
;
Ulcer
3.Diarrhea(Based on acute infectious diarrhea).
Geom Seog SEO ; Suck Chei CHOI
Korean Journal of Medicine 2010;78(1):49-53
No abstract available.
5.Diagnosis and Treatment of Colon Diverticulitis.
Geom Seog SEO ; Suck Chei CHOI
Korean Journal of Medicine 2013;85(6):563-570
Colonic diverticular disease is the common conditions in industrialized and westernized countries, but it is relatively rare in areas such as Asia. Colonic diverticula are asymptomatic in most cases, only 10-25% develop diverticulitis and 1% finally gets surgery. The location of colonic diverticulitis are significantly different in Western countries and Asia. Left-sided diverticulitis is common in Western countries, while in Asians, right-sided diverticulitis is more prevalent. A CT scans is commonly used to diagnose diverticulitis and its complication such as abscess, obstruction, fistula and perforation. It also has been used in percutaneous drainage of diverticular abscess and predicting the success of medical therapy. After resolution of clinical attack of diverticulitis, colonoscopy can be performed to exclude colon cancer. The current therapeutic approaches for colonic diverticulitis are relieving symptoms and preventing complications. Uncomplicated diverticulitis is successfully treated with antibiotics, bowel rest and pain control, while complicated diverticulitis require surgical consultation. Treatment strategy of recurrent diverticulitis depends on age and comorbid diseases as well as the frequency and severity of subsequent attacks.
Abscess
;
Anti-Bacterial Agents
;
Asia
;
Asian Continental Ancestry Group
;
Colon*
;
Colonic Neoplasms
;
Colonoscopy
;
Diagnosis*
;
Diverticulitis*
;
Diverticulitis, Colonic
;
Diverticulum, Colon
;
Drainage
;
Fistula
;
Humans
;
Tomography, X-Ray Computed
6.Gastric Wall Abscess.
Jun Young LEE ; Suck Chei CHOI ; Geom Seog SEO
The Korean Journal of Gastroenterology 2011;57(5):327-329
No abstract available.
Abscess/*diagnosis/microbiology
;
Anti-Bacterial Agents/therapeutic use
;
Cephalosporins/therapeutic use
;
Gastroscopy
;
Humans
;
Klebsiella Infections/*drug therapy
;
Klebsiella pneumoniae/*isolation & purification
;
Male
;
Middle Aged
;
Stomach Diseases/*diagnosis/microbiology
;
Tomography, X-Ray Computed
7.Localized Gastric Amyloidosis with Kappa and Lambda Light Chain Co-Expression.
Yong Hwan AHN ; Ye Young RHEE ; Suck Chei CHOI ; Geom Seog SEO
Clinical Endoscopy 2018;51(3):285-288
Esophagogastroduodenoscopy for cancer screening was performed in a 55-year-old woman as part of a health screening program, and revealed a depressed lesion approximately 20 mm in diameter in the lesser curvature of the mid-gastric body. Several biopsy specimens were collected as the lesion resembled early gastric cancer; however, histopathologic evaluation revealed chronic active gastritis with an ulcer and amorphous eosinophilic material deposition. Congo red staining identified amyloid proteins, and apple-green birefringence was shown using polarized light microscopy. Immunohistochemical staining revealed the presence of kappa and lambda chain-positive plasma cells. There was no evidence of underlying plasma cell dyscrasia or amyloid deposition in other segments of the gastrointestinal tract. Echocardiography and computed tomography of the chest, abdomen, and pelvis did not show any significant findings. Thus, the patient was diagnosed with localized gastric amyloidosis with kappa and lambda light chain coexpression.
Abdomen
;
Amyloidogenic Proteins
;
Amyloidosis*
;
Biopsy
;
Birefringence
;
Congo Red
;
Early Detection of Cancer
;
Echocardiography
;
Endoscopy, Digestive System
;
Eosinophils
;
Female
;
Gastritis
;
Gastrointestinal Tract
;
Humans
;
Mass Screening
;
Microscopy, Polarization
;
Middle Aged
;
Paraproteinemias
;
Pelvis
;
Plaque, Amyloid
;
Plasma Cells
;
Stomach Neoplasms
;
Thorax
;
Ulcer
8.A Case of Duodenal GIST Accompanied with Neurofibromatosis-1, Presenting with Gastrointestinal Bleeding.
Sung O SEO ; Hyo Jung OH ; Ki Hoon KIM ; Chang Soo CHOI ; Geom Seog SEO ; Tae Hyeon KIM ; Ki Jung YUN ; Suck Chei CHOI
Korean Journal of Gastrointestinal Endoscopy 2007;35(4):254-257
Gastrointestinal stroma tumors (GISTs) are CD117- positive primary mesenchymal tumors of the gastrointestinal tract and are noted to have a possible non-random association with neurofibromatosis-1 (NF-1, Von Recklinghausen disease). We report a case of a duodenal GIST presenting with gastrointestinal bleeding in a 74-year-old female, and this condition was accompanied with NF-1. A upper gastrointestinal endoscopy and abdominal computed tomography scan revealed several submucosal tumors in the duodenum, jejunum and ileum. Histological and immunohistochemical studies on the surgical resection specimen revealed gastrointestinal stromal tumors of an uncommitted type. The patient was treated with local excision of the tumors and is now in a favorable state.
Aged
;
Duodenum
;
Endoscopy, Gastrointestinal
;
Female
;
Gastrointestinal Stromal Tumors
;
Gastrointestinal Tract
;
Hemorrhage*
;
Humans
;
Ileum
;
Jejunum
9.A Case of Transverse Colon Perforation after Colonoscopy in a Patient withEnterocolitis Caused by Non-typhoidal Group D Salmonella.
Ki Hoon KIM ; Suck Chei CHOI ; Tae Hyeon KIM ; Geom Seog SEO ; Chang Soo CHOI ; Sung O SEO ; Mi Jin SONG ; Ji Hyun CHO
Korean Journal of Gastrointestinal Endoscopy 2008;36(6):395-400
Clinical manifestations of Salmonella infection are variable such as enterocolitis, bacteremia, enteric fever, focal infection and asymptomatic carrier status. Among these presentations, enterocolitis is the most common clinical manifestation and can be diagnosed by the use of fecal specimens. Patients with severe infectious colitis are at increased risk of developing a colon perforation after colonoscopy due to colon trauma. We report a case of a 31-year-old woman with transverse colon perforation after colonoscopy that was diagnosed with enterocolitis caused by infection with non-typhoidal group D Salmonella.
Adult
;
Bacteremia
;
Colitis
;
Colon
;
Colon, Transverse
;
Colonoscopy
;
Enterocolitis
;
Female
;
Focal Infection
;
Humans
;
Megacolon, Toxic
;
Salmonella
;
Salmonella Infections
;
Typhoid Fever
10.A Tuberculous Peritonitis Presenting as Submucosal Tumors.
Chang Soo CHOI ; Geom Seog SEO ; Ki Hoon KIM ; Bong Joon YANG ; Yong Hwan AHN ; Suck Chei CHOI
Intestinal Research 2009;7(1):60-63
Tuberculous peritonitis is not an uncommon disease, but the diagnosis is often missed and delayed because of the variability of disease presentation and non-specific clinical manifestations. In this report, we discuss a rare case of tuberculous peritonitis which presented as a submucosal mass in the colon. A 61-year-old woman registered at our hospital for a physical check-up. She had a weight loss of 3 kg over the past 6 months. The colonoscopic findings showed submucosal lesions (4 and 6 mm in size, yellow in color, and hard) which were suspected to be a carcinoid tumor. However, an abdomen-pelvic CT scan and laparoscopic findings suggested peritoneal tuberculosis. The result of laparoscopic biopsies was chronic granulomatous inflammation without caseous necrosis. After the standard anti-tuberculosis medications for 6 months, the previous lesions on the CT scan had resolved.
Biopsy
;
Carcinoid Tumor
;
Colon
;
Female
;
Humans
;
Inflammation
;
Middle Aged
;
Necrosis
;
Peritonitis, Tuberculous
;
Weight Loss