1.Determination of 2, 3, 5, 4′-stilbene glucoside in Xuezhiping Capsules by HPLC
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Objective To determinate the content of 2, 3, 5, 4′-stibene glucoside in Xuezhiping Capsules. Method HPLC was performed with Diamosil~(TM)C_(18) column, a mobile phase of acetonitrile-water (20: 80), the detection wavelength at 320nm and the flow rate being 1.0 mL/mL. Results 2, 3, 5, 4′-stilbene glucoside has a good linear within 0.0267~2.6640 ?g and the average recovery was 99.62% with RSD 1.32%. Conclusion This method is convenient and efficient and can be used for the quality control of Xuezhiping Capsules.
2.CLINICAL AND ANIMAL EXPERIMENTAL STUDY ON THREE SERUM ENZYMES IN LIVER CIRRHOSIS
Genyuan YANG ; Guangcai YANG ; Jianjun FENG ; Yuecai ZHANG ;
Medical Journal of Chinese People's Liberation Army 1981;0(06):-
The present study consisted of the assay of the POA activity (SGPT. SGOT and SMAO) in 20 cases of cirrhosis of liver. Similar study was also done in CCl4 rabbit model Pathological examination was carried out for the animal livers.By comparing the clinical observations of patients with the results of experimental animal we could see that the estimation of POA activity might reflect the degree of liver cell degeneration, necrosis and fibrosis of cirrhotic patients, and they could also be used as a biochemical index for evaluation of the therapeutic effect. It was considered further that the prognosis of cirrhosis could be predicted if serum aldolase isoenzyme A (and/ or serum AFP level) activity was estimated in addition.
3.Eccrine angiomatous hamartoma:a clinicalopathologic analysis of 4 cases
Xiaohong GUO ; Genyuan YANG ; Chubin LI ; Lijuan WANG ; Jie ZHANG ; Xiujuan YUAN
Chinese Journal of Pathology 2016;45(7):467-471
Objective To investigate the clinical and histopathologic features , diagnosis and differential diagnosis of eccrine angiomatous hamartoma ( EAH ).Methods Four cases of eccrine angiomatous hamartoma were studied by light microscopy and immunohistochemical staining along with review of the literature.Results There were 3 male and 1 female patients at diagnosis in age of 4 months, 3.5 years, 5.5 years and 14.0 years, respectively.Tumor sites included the left little finger (1 case), right index finger (1 case), lower back (1 case) and knee (1 case).Clinically, most cases presented as a solitary, flesh or reddish papule , plaque or nodule with size of 0.4-6.0 cm in diameter.The skin lesions in 3 cases enlarged commensurate with the growth of the patients , and local hyperhidrosis in one case.Histologically, EAH was characterized by proliferation of well-differentiated eccrine secretory and ductal elements closely associated with thin-walled angiomatous channels in the middle or deep dermis and subcutaneous tissue.By immunohistochemistry , the vascular components were positive for CD 31, CD34 and factorⅧrelated antigen while the eccrine glands were positive for S-100 protein, CEA, EMA, CAM5.2 and GCDFP15.Local surgical resection was performed in 4 cases and follow-up data (0.5 to 4.5 years) showed no recurrence.Conclusion EAH is a rare, benign cutaneous hamartoma.Combination of clinical manifestations , histological changes and immunohistochemical findings is useful for the diagnosis and differential diagnosis .