1.Clinical Study on Acupuncture Treatment of Atrophic Gastritis with Reducing within Reinforcing Manipulations
Yaochi WU ; Chongmiao WANG ; Genwei FEI ; Chouping HAN
Journal of Acupuncture and Tuina Science 2005;3(2):9-11
Purpose: To observe the clinical efficacy on acupuncture treatment of atrophic gastritis. Methods: Points Zhongwan (CV 12) and Zusanli (ST 36) were selected to treat 38patients with atrophic gastritis by reducing within reinforcing manipulations. The curative effect was evaluated and compared with that in a medication group. Results: A comparison of the comprehensive clinical efficacy between the acupuncture group and the medication group showed that the effective rate was 86.8% and 84.2% respectively. Statistical analysis showed that there was no significant difference in clinical effect between the two groups (P>0.05).Conclusion: Acupuncture can get the same effect as medication in treating atrophic gastritis.
2.Hemodynamic abnormality in patients with primary trigeminal neuralgia
Huipeng LU ; Zhan LIU ; Genwei WANG ; Shengzhong TAO ; Guangming NIU ; Zaibin WANG ; Keliang CHANG ; Donghua JIN
Chinese Journal of Neurology 2022;55(6):619-625
Objective:To investigate specificity of neurovascular compression in patients with primary trigeminal neuralgia (PTN) by three-dimension reconstruction and computational fluid dynamics.Methods:Clinical characteristics and preoperative magnetic resonance imaging (MRI) data of 20 patients with both PTN and single artery compression (PTN group) and 10 patients without PTN but having neurovascular contact in MRI images (control group) in the Second Affiliated Hospital of Zhengzhou University from January 2018 to December 2019 were collected and analyzed. After three-dimension reconstruction of the MRI images, curvature of the arterial loop, angle between the plane of arterial loop and the trigeminal nerve and location of the compression were observed. Then bidirectional structure-fluid coupling based on the optimized stereolithography models of arterial loop and nerve were processed by ANSYS 19.2 software. In the location of the compression of contact, equivalent stress (ES) of arterial loop on the nerve, shearing stress (SS) of the blood flow and local deformation of the nerve were iteratively computed. All parameters were analyzed and compared between the PTN group and the control group, and the correlation analysis was proceeded between the anatomical parameters and hemodynamical parameters.Results:The curvature of arterial loop [0.21(0.12) mm -1vs 0.13(0.07) mm -1, U=34.00, P<0.05], the angle between vascular loop and nerve [69.70(30.67)° vs 43.40(37.21)°, U=38.00, P<0.05] in the PTN group were significantly greater than those in the control group, and the location of compression was significantly closer to the root of nerve in the PTN group [PTN group: (4.23±1.29) mm vs control group: (5.54±1.85) mm, t=-2.26, P<0.05]. The average SS [15 952.48(5 365.56) Pa vs 12 501.97(6 355.26) Pa, U=53.00, P<0.05], ES [24 965.65(7 693.22) Pa vs 14 992.99(9 824.08) Pa, U=32.00, P<0.05] in the PTN group were significantly greater than those in the control group. The curvature of arterial loop was positively correlated with the SS ( r=0.931, P<0.05) and ES ( r=0.962, P<0.05), and the latter two ( r=0.787, P<0.05; r=0.853, P<0.05) were positively correlated with the local neural deformation. Conclusions:In patients with PTN, offending artery compresses the root of nerve by greater arterial curvature and angle between the arterial loop and nerve. These anatomical differences will cause significantly greater SS, ES and local neural deformation.