No abstract available.
Genome, Human* ; Human Genome Project* ; Humans ; Humans*

The chronology of the reseach on human genome on the second half of XXth century were: 1953, 1957, 1966, 1972, 1975, 1983, 1984, 1985, 1988, 1990, 1995, 1998, 1999 and 2000
Genome, Human ; Chronology

In June 26, 2000, doctor Collins and Venter released the results of research of human genome. As the results, the human genome has 3.12 billion nucleotides (nu) of which the sequence of 97% nucleotides were identified. There were 60.000 -100.000 genes found among 3.12 billion nucleotides. The human genome is identical from one to another (99.9%) although there is a difference of races, skin color. Genome is a foundation of the biology and considered as an electronic central nerve of the cells. The basic techniques for research on genes comprise the DNA recombination, chemical analysis (MAXAM GILBERT) and method SANGER.
Genome, Human ; Biology ; DNA

No abstract available.
Genome, Human* ; Humans ; Humans*

An increasing number of primate genomes are being sequenced. A direct comparison of repeat elements in human genes and their corresponding chimpanzee orthologs will not only give information on their evolution, but also shed light on the major evolutionary events that shaped our species. We have developed REPEATOME to enable visualization and subsequent comparisons of human and chimpanzee repeat elements. REPEATOME (http://www.repeatome.org/) provides easy access to a complete repeat element map of the human genome, as well as repeat element-associated information. It provides a convenient and effective way to access the repeat elements within or spanning the functional regions in human and chimpanzee genome sequences. REPEATOME includes information to compare repeat elements and gene structures of human genes and their counterparts in chimpanzee. This database can be accessed using comparative search options such as intersection, union, and difference to find lineage-specific or common repeat elements. REPEATOME allows researchers to perform visualization and comparative analysis of repeat elements in human and chimpanzee.
Genome ; Genome, Human ; Humans* ; Pan troglodytes* ; Primates

Genome-wide association (GWA) studies are the method of choice for discovering loci associated with common diseases. More than a thousand GWA studies have reported successful identification of statistically significant association signals in human genomes for a variety of complex diseases. In this review, I discuss some of the issues related to the future of GWA studies and their biomedical applications.
Genome, Human ; Genome-Wide Association Study ; Humans

Recent rapid advances in genetic research are ushering us into the genome sequence era, where an individual's genome information is utilized for clinical practice. The most spectacular results of the human genome study have been provided by genome-wide association studies (GWASs). This is a review of the history of GWASs as related to my work. Further efforts are necessary to make full use of its potential power to medicine.
Genetic Research ; Genome ; Genome, Human ; Genome-Wide Association Study ; HapMap Project ; Human Genome Project ; Humans

The Human Genome Project is an international cooperative project that launched in 1990 and completely finished in April 14, 2003. The discovery of pathogenic genes is promising that light up the pathogenesis of many diseases in human. In the future, the understanding of these genes is helpful for patients and physicians, but the first advantages are in diagnosis and prognosis. It’s hoped to bring about new more effective therapies tailored for each patient according to his genome in the next 5 years
Genome, Human ; Gene Conversion ; medicine

The completion of the rough draft of the human genome is a remarkable achievement. It provides the overall structures of huge DNA molecules that constitute the genome and an outline of the information needed to create a human being This paper reviewed new ideas, projects, and scientific advances made by the Human Genome Project. We also discussed the future of medicine and biomedical research in postgenomic era.
DNA ; Genome ; Genome, Human* ; Genomics ; Human Genome Project* ; Humans ; Humans* ; Proteome ; Proteomics

The comparative analysis of the human and primate genomes including the chimpanzee can reveal unique types of information impossible to obtain from comparing the human genome with the genomes of other vertebrates. PrimateDB is an open depository server that provides primate genome information for the comparative genome research. The database also provides an easy access to variable information within/between the primate genomes and supports analyzed information, such as annotation and retroelements and phylogeny. The comparative analyses of more primate genomes are also being included as the long-term objective.
Genome* ; Genome, Human ; Humans ; Pan troglodytes ; Phylogeny ; Primates* ; Retroelements ; Vertebrates