Objective To analyze the predictive factors of fever after percutaneous renal stone surgery,and to provide reference for clinical treatment.Methods A total of 147 patients underwent percutaneous nephrolithotomy in after operation was chosen in the Department of Urology in our hospital from January 2014 to January 2016.According to the existence of fever,patients were divided into fever (n =25,heating rate 17.0％) and control (n =122) groups.Preoperative information were collected,including age,gender,preoperative serum creatinine,stone size and shape,the involvement of calyceal number,water,urine culture results,operative time,blood loss,intraoperative perfusion volume,pyonephrosis,puncture channel length,hospitalization time and other information including intraoperative,postoperative information including fever,and postoperative renal fistula complications if there is information.SPSS 18.0 was used for statistical analysis.Results The fever group stone surface area,CT value affected calyx number,stone shape,stone properties,the involvement of calyceal number,degree of hydronephrosis,operative time,intraoperative blood loss,intraoperative perfusion,hospitalization time,and renal fistula complication rates were higher than the control group (P ＜ 0.05).There were no significant differences between two groups (P ＞0.05).The results of Logistic regression analysis found that the stone surface area (OR =5.19),stone,stone shape (OR =7.86) properties (OR =3.87),operation time (OR =5.68),intraoperative perfusion (OR =5.24),and renal fistula complications (OR =2.65) for the influence factors of fever.Conclusions The stone surface area is large,stone nature infection stones,stone shape for staghorn calculi,longer operation time,and intraoperative perfusion of large renal fistula complications were more prone to postoperative fever in postoperative.

Hepatocellular carcinoma (HCC) is a common malignant tumor in China, and most of the patients have a background of chronic HBV infection. Nucleos(t)ide drugs (NAs) are currently recommended by major guidelines as a first-line treatments for chronic hepatitis B. However, it is still clinically possible to observe that some patients who have acquired virological response (HBV DNA below the lower detection limit) after NAS treatment progress to HCC, and its mechanism of development is still unclear. In this review, the mechanism relevant to HCC progression in treatment of chronic hepatitis B patients with NAs is analyzed mainly from the aspects of gene integration and persistent inflammatory injury.

Objective:To explore the correlation between mechanical complications and paraspinal muscle degeneration following posterior single-segment osteotomy corrective surgery for chronic osteoporotic vertebral compression fractures (OVCF).Methods:A retrospective analysis was conducted on 80 patients who underwent surgery between January 2008 and January 2021 at Peking University Third Hospital. These patients, who developed kyphotic deformity following OVCF, included 17 males and 63 females with a mean age of 63.21±8.07 years (range, 47-77 years). Postoperative mechanical complications included proximal junctional kyphosis (PJK), screw loosening, adjacent segment degeneration (ASD), and distal junctional kyphosis or failure. Patients were compared based on the occurrence of mechanical complications in relation to fat infiltration (FI), relative gross cross-sectional area (rGCSA), and relative functional cross-sectional area (rFCSA) of the paraspinal muscles. Binary logistic regression analysis was used to identify risk factors for postoperative complications.Results:Among the 80 patients, 19 developed PJK, while 61 did not. The PJK group exhibited significantly higher paraspinal muscle FI (0.44±0.05) compared to the non-PJK group (0.38±0.10, P<0.05). Screw loosening occurred in 7 cases, with 73 cases remaining stable. Those with screw loosening demonstrated higher paraspinal muscle FI (0.47±0.05) than those without (0.38±0.09, P<0.05). Thirty patients experienced ASD, while 50 did not. The ASD group had higher paraspinal muscle FI (0.45±0.07) and lower rFCSA (0.09±0.03) compared to the non-ASD group (0.36±0.10 and 0.13±0.06, respectively, P<0.05). Logistic regression analysis indicated that paraspinal muscle FI and rFCSA were not independent risk factors for developing ASD. Twenty-three patients experienced distal junctional kyphosis or failure, while 57 did not; those with complications exhibited higher paraspinal muscle FI (0.48±0.08) and lower rGCSA (0.16±0.04) and rFCSA (0.09±0.03) compared to those without complications (0.37±0.09, 0.20±0.09, and 0.13±0.06, respectively, P<0.05). Logistic regression analysis suggested that paraspinal muscle FI, rGCSA, and rFCSA were not independent risk factors for developing distal junctional kyphosis or failure. Conclusion:Mechanical complications following corrective surgery for chronic OVCF-related kyphosis may be associated with increased paraspinal muscle FI. Additionally, the occurrence of ASD and distal junctional kyphosis or failure may correlate with reduced paraspinal muscle rFCSA

Objective:To systematically evaluate whether the early use of bracing after posterior lumbar fusion has advantages in terms of the improvement of clinical outcomes such as pain, functional disability, fusion rate, and complication rate in patients with lumbar degenerative diseases.Methods:All randomized controlled trials of bracing performed after posterior lumbar fusion in patients with lumbar degenerative diseases were searched in Pubmed, Web of Science, Embase, China national knowledge infrastructure (CNKI) and Wanfang database from January 1990 to May 2022. The data extracted were authors, year of publication, nationality, subject characteristics, sample size, surgical protocol, type and time of bracing, follow-up duration, preoperative and postoperative Oswestry disability index (ODI) and visual analogue scale (VAS), postoperative fusion rate and complication rate. The Cochrane Risk of Bias tool was used to evaluate the risk of bias. The use of fix- or random-effect models was depended on the magnitude of heterogeneity. Data analysis was performed using Stata 17.0 statistical software for meta analysis.Results:A total of five randomized controlled trials were included, all in English, with a total of 362 patients (male 144, female 218). The results of meta-analysis showed that there was no statistically significant difference in the improvement of ODI scores [ MD=1.25, 95% CI(-2.39, 4.88), P=0.501]and VAS scores[ MD=0.21, 95% CI(-0.22, 0.63), P=0.340]between the brace group and the control group after operation. In terms of fusion rate, there was no significant difference between the brace group and the control group[ OR=0.59, 95% CI(0.25, 1.38), P=0.224]. In addition, there was also no significant difference in the incidence of postoperative complications between two groups[ OR=1.12, 95% CI(0.58, 2.15), P=0.735]. Conclusion:The early use of bracing after lumbar fusion has no significant advantages in improving symptoms and functional recovery, fusion rate and surgical complications. The necessity of postoperative bracing after posterior lumbar fusion requires further high-quality research to prove.