2.Clinical analysis of borderline ovarian tumor with 60 cases
Chinese Journal of Postgraduates of Medicine 2011;34(24):17-19
ObjectiveTo investigate the clinical features of borderline ovarian tumor (BOT).MethodThe clinical features, clinical stage, malignant potential, pathological type, the positive rate of serum CA125 were analyzed in 60 patients with pathological diagnosis of BOT. ResultsSerous cystadenoma was the main pathological type, accounted for 60.0% (36/60). The occurrence of focal canceration in serous cystadenoma[22.2% (8/36)]was higher than that in mucinous cystadenoma[5.3%(1/19)](P< 0.05). The positive rate of CA125 was 51.7%(31/60). The positive rate of CA125 in BOT with micro-dip or focal canceration[65.0%(13/20) and 81.8%(9/11)]was higher than that in simple BOT [31.0%(9/29)](P<O.05),but there was no significant difference between BOT with micro-dip and BOT with focal canceration (P> 0.05 ). ConclusionsBOT is low malignant potential and preoperative diagnosis is difficult because of the typical clinical symptoms. CA125 is not sensitive to pure BOT. Women of childbearing age should regularly check for ovarian tumor by ultrasonography and preoperative serum CA125 test can be combined with micro-dip on the BOT and those made with preoperative focal predict cancer diagnosis. Aggressive surgical treatment is necessarily as soon as possible and rapid intraoperative pathological examination to reduce cancer risk.
3.Technical difficulties and countermeasures of caudate lobectomy
Chinese Journal of Digestive Surgery 2013;(1):30-33
Caudate lobectomy is still a great challenge for surgeons due to unique anatomy of caudate lobe.A 38-year-old male patient with a huge recurrent hepatic cancer (diameter =16 cm) in caudate lobe received caudate lobectomy with portal triad and inferior vena cava clamping.The operation was paused due to hemorrhage (volume of blood loss =1000 ml).After heat preservation and blood transfusion,the caudate lobectomy was completely removed with inferior vena cava clamping.The patient gradually recovered,and no tumor recurrence was detected during the follow up (14 months).Caudate lobectomy could be safely carried out under the condition of accurate preoperational estimation,clear indication for surgery and precise hepatectomy.
4.Leptin in gastric cancer
Journal of International Oncology 2010;37(8):604-606
Leptin promotes proliferation of cancer cells via various signal transduction pathways and contributes to angiogenesis in gastric cancer. Leptin expression level is significantly higher in gastric cancer than in normal gastric mucous tissues, and correlates with clinicopathological features such as differentiation,tumor size and distant metastasis. Leptin has become a prognostic factor and a new therapy target of gastric cancer.
5.The relationship between electrocardiogram and infarction-related artery in 69 cases of acute inferior myocardial infarction
Chinese Journal of General Practitioners 2009;8(1):56-57
The results of electrocardiogram and coronary angiography were compared in 69 patients with acute inferior myocardial infarction(right ventricle, later wall). The sensitivity and specificity of ST segment elevation Ⅲ> Ⅱ in diagnosis of right coronary artery (RCA) as the infarction related artery (IRA) were 92.00% and 84. 21% respectively;those for ST segment depression avL > Ⅰ were 90. 00% and 89. 5% respectively. Therefore if ST-elevation Ⅲ > Ⅱ , ST-depression avL > Ⅰ and no depression on STV1 and V2 in acute inferior myocardial infarction may highly indicate that RAC be the IRA;on the contrary, the LCX be the IRA.
6.Micrometastasis of non-small cell lung cancer and its detection
Journal of International Oncology 2008;35(7):507-509
Micrometastasis of carcinoma is one of the most significant pieces of evidence for molecular staging.Detection of micrometastasis of non-small-cell lung cancer plays a significant role in staging precisely,guiding treatment and predicting the prognosis of patients.This review is focused on the latest developments of markers such as CK19,LUNX,CEA mRNA,oncogene and anti-oncogene.The sites about micrometastasis of non-small-cell lung cancer are usually reported in lymph node and bone marrow,rarely in pleural cavity and increasingly in peripheral blood.