No abstract available.
Gelatin Sponge, Absorbable* ; Hemorrhage* ; Thrombin*

The author report a huge torcular meningioma, fed only by right occipital artery, which was removed after the preoperative transfemoral catheter embolization with gelfoam plugs to reduce operative blood loss.
Arteries ; Catheters* ; Gelatin Sponge, Absorbable ; Meningioma*

Renal arterial embolization was induced experimentally in rabbits using autologous blood clot, Gelfoam, bariumsulfate, Ivalon(Polyvinyl alcohol)and ethanol. Microvascular changes were studied angiographically,microangiographically and histopathologically. The results were as follows: 1. The microangiographic findings ofrenal artery embolization were arterial occlusion, irregular arrangement, spiralling, dilatation, narrowing andcollateral vessel formation. 2. Recanalization of embolized vessels were noted after injection of autologous bloodclot and Gelforam only. 3. Collateral vessel formations were demonstrated in entire cases of renal arterialembolization (36/37). 4. After injection of Ivalon, recanalization of embolized vessel was not demonstrated butcollateral vessel formation were demonstrated microangiographically in all cases. 5 After injection of ethanol,collateral vessels were poorly developed microangiographically than other groups. 6. Embolic effect of ethanol wasnoted in central vessel but as well as in peripheral vessel. It was considered that ethanol is the most effectiveagent for permanent renal arterial occlusion.
Arteries ; Dilatation ; Ethanol ; Gelatin Sponge, Absorbable ; Rabbits

In a series of 20 young rats, three cortical lesions were made in each hemisphere. Two of these lesions were filled with avitene and gelfoam, while the third was left empty as a control. The animals were killed successively on weeks 1, 2, 4 and 8 after the operation. The results were as follows : 1) Although there was no difference in the type of tissue reactions, avitene was more rapid and profound than gelfoam in the process and degree of inflammatory reaction at the same periods. 2) Avitene biodegradaded more rapidly than gelfoam. 3) The extent of fibrosis and adhesion to the surrounding brain tissues were not grossly different between these two agents but more profound histopathologically in avitene at the same periods. With these results, we could conclude that the avitene was superior to the gelfoam as the hemostatic agent in neurosurgical area.
Animals ; Brain* ; Collagen ; Fibrosis ; Gelatin Sponge, Absorbable ; Rats

In a series of rabbits, two craniectomies were made in both side of the parietal hone. Each lesion was filled with gelfoam, lyocura, fat and dural film. Five rabbits were left empty as a control group. The animals were killed in one month after the operation. The degree of adhesion between the soft tissue of the scalp and various dural substitute was evaluated at the time of operative dissection and studied histopathologically. The results were as follows. 1) The insertion of dural substituted substances can prevent the adhesion between the scalp and dura mater. 2) The dural film was most effective in prevention of adhesion. 3) The dural film inserted group exhibited inflammatory reaction. 4) The gelfoam, lyodura and fat inserted groups were though to have had a moderate prevention effect of adhesion. With these results, we could conclude that the insertion of material between the dura and scalp can prevent adhesion. However the ideal inserted material which can pevent inflammatory reaction and adhesion has not been determined. At this point we have not found and ideal substitute. To get an ideal material for prevention of adhesion, further intensive study is required.
Animals ; Dura Mater ; Gelatin Sponge, Absorbable ; Rabbits ; Rabeprazole ; Scalp

PURPOSE: We assessed the long term efficacy and complications of angiographic embolization of hypogastric arteries in treating the intractable bladder hemorrhage induced by radiation. MATERIALS AND METHODS: From January 1990 to December 1997, a total of 43 patients with radiation induced hemorrhagic cystitis were evaluated. Of 43 patients, 5 patients were treated by bilateral selective angiographic embolization of the anterior branches of the hypogastric arteries. The embolic material used in all patients was gelfoam. RESULTS: Five patients with intractable bladder hemorrhage were treated by bilateral selective embolization of the anterior branches of the hypogastric arteries by gelfoam and successful in completely stopping or considerably decreasing intractable bladder hemorrhage in all patients. The average number of treatments was 1.6(range 1 to 2). There was no significant sequelae ocurred as a consequence of simultaneous bilateral occlusion of the hypogastric arteries. CONCLUSIONS: Radiation induced hemorrhagic cystitis that do not respond to irrigations with chemical cauterizing agents or transurethral fulguration of bleeding vessels can be successfully treated with bilateral selective angiographic embolization of the anterior branches of the hypogastric arteries.
Arteries* ; Cystitis* ; Gelatin Sponge, Absorbable ; Hemorrhage ; Humans ; Urinary Bladder

PURPOSE: To evaluate the air contamination of the gelfoam in the angio-intervention room. MATERIALS AND METHODS: After exposing four groups of gelfoam(group A1 : gelfoam fragment, group A2 : gelfoam fragment+ saline +contrast media, group B1 : gelfoam powder, group B2 : gelfoam powder + saline + contrast media) to air in the angio-intervention room, we inoculated gelfoam in each group to 30 agar plates each at every fifteen minutes for one hour with aseptic cotton buds. Cultivating them in the incubator for one day, we evaluated the growth of bacteria or fungus. RESULTS: Out of 480 inoculated agar plates, the growth of coagulase(-) staphylococci was visible in 14 ; in group A1, two at 30 minutes, three at 45 minutes, and four at 60 minutes ; in group A2, one at 45 minutes and two at 60 minutes ; in group B1 and B2, one each at 45 minutes. The stastical analysis on bacterial contamination according to time sequence and group revealed no significance(p<0.05). CONCLUSIONS: If gelfoam is exposed to room air for less than 30 minutes, it is possible to reduce contamination by air-borne bacteria. Since coagulase-negative Staphylococci resistant to commonly used antibiotics, it is ideal to reduce exposure of gelfoamto room air for less than 30 minutes.
Agar ; Anti-Bacterial Agents ; Bacteria ; Fungi ; Gelatin Sponge, Absorbable* ; Incubators

Transcatheter arterial embolization was applied in 7 cases of hepatic disease including hemobilia of various causes and malignant tumors at Department of Radiology, Seoul National University Hospital during recent several years. The embolic materials were autologous blood clot and Gelfoam particle. Successful control of bleeding or devascularization of tumor vessel was made in 6 of the 7 patients. There was no serious complications; however, post embolization syndrome was found including pain, fever, nausea and vomiting in all cases and subsided after a few days. Transcatheter hepatic arterial embolization is suggested to be a safe and effective treatment in control of hemobilia and devascularization of malignant hepatic tumors.
Fever ; Gelatin Sponge, Absorbable ; Hemobilia ; Hemorrhage ; Humans ; Nausea ; Seoul ; Vomiting

The intractable pneumothorax with continuous air leakage, emphysematous lung and high operative risk treated by selective bronchial occlusion has been seldomly reported abroad. The bronchus responsible for air leakage was occluded with such materials as fibrin glue, gelatin sponge and oxidized regenerated cellulose(surgicel). We performed selective bronchial occlusion by flexible fiberoptic bronchoscopy with gelfoam in two cases. There was no complication after the procedure; therefore, we report the treatment for intractable pneumothorax by bronchoscopy with gelfoam packing.
Bronchi ; Bronchoscopy ; Fibrin Tissue Adhesive ; Gelatin ; Gelatin Sponge, Absorbable ; Lung* ; Pneumothorax* ; Porifera

PURPOSE: To report on the safety and efficacy of superselective transcatheter arterial chemoembolization( TACE) of tumor feeding branches originating from the cystic artery for the treatment of hepatocellular. MATERIALS AND METHODS: From, May 1995 to, September 1999, eleven HCC patients aged between 38 and 82 (mean, 57.4) years with tumor-feeding branches originating from the cystic artery underwent TACE. In eight, for whom superselection of these branches was possible, TACE was done with the use of Gelfoam and a mixture of Lipiodol and cisplatin, while for three, for whom superselection was impossible, a mixture of Lipiodol and cisplatin only was used. Immediately after TACE, remnant tumor staining was angiographically evaluated,and tumor response was determined by follow-up CT at one month. After procedure, the development of cholecystitis was assessed clinically. RESULTS: Post-TACE angiography showed remnant tumor staining in one patient who underwent embolization with Gelfoam and the mixture of Lipiodol and cisplatin, and in one for whom the mixture of Lipiodol & cisplatin only was used. Among the eight for whom Gelfoam and the mixture of Lipiodol and cisplatin was used,one-month follow-up CT showed compact Lipiodol uptake in five, partial Lipiodol uptake in three, no change in tumor size in six, increased tumor size in one, and decreased tumor size in one. Among the three for whom the mixture of Lipiodol and cisplatin only was used, one-month follow-up CT showed neither Lipiodol uptake nor change in tumor size in one patient, partial Lipiodol uptake and increased tumor size in one, and compact Lipiodol uptake and decreased tumor size in one. Cholecystitis developed in only one patient who underwent embolization with Gelfoam and the mixture of Lipiodol and cisplatin, but was cured by conservative treatment. CONCLUSION: Superselective TACE of tumor feeding branches originating from the cystic artery seems to be a safe and effective method for the treatment of hepatocellular carcinoma.
Angiography ; Arteries* ; Carcinoma, Hepatocellular* ; Cholecystitis ; Cisplatin ; Ethiodized Oil ; Follow-Up Studies ; Gelatin Sponge, Absorbable ; Humans