The authors presented two cases of wasp sting on the eyeball. In the first case the ocluar involvements following the sting of wasp on the central cornea were desquamation of the central corneal epithelium, striated keratitis, bullous keratitis, conneal edema, stromal staining by fluorescein dye to the depth of about two thirds of the cornea, auterior polar cataract, irreversible depigmentation of the iris, stromal atrophy of the iris mydrasis which did not respond even to repeated instillations of eserine. Corneal lesions led to dystrophic changes later. The second case showed thick cortical cataract, progressive decrease of intraocular pressure and complete blindness without significant corneal and iris involvements following wasp sting on the medial bulbar conjunctiva. The cause of the complete blindness and the progressive decrease of intraocular pressure is unexplainable but it may be a direct effect of venom onto the optic nerve and the ciliary body.
Atrophy ; Bites and Stings* ; Blindness ; Cataract ; Ciliary Body ; Conjunctiva ; Cornea ; Edema ; Epithelium, Corneal ; Fluorescein ; Intraocular Pressure ; Iris ; Keratitis ; Optic Nerve ; Physostigmine ; Venoms ; Wasps*

Authors presented two cases of typical Groenblad-Strandberg's syndrome and reviewed concerning pathogenesis, histology, heredity and its related conditions. Followings are to be considered in these cases. 1. Pseudoxanthoma elasticum, generally considered; mainly appears from 25 to 50 years of life, but we met in case 2 that he was eleven years old. 2. In ocular complications Case 1 showed disciform macular degeneration of the left eye and macular hemorrhages in superficial layers of retina of the right eye. The other case was several retinal exudates of the left eye without any amcular complications. 3. Case 2 had suggestive signs of Paget's disease in radiograms of the skull and pelvic bone. Routine laboratery studies including serum calcium, phosphorus and alkaline phosphatase were normal. 4. Suspicious heroditary occurrence was noted in case 2. 5. There were no significant abnormalities in blood and cardiovascular system.
Alkaline Phosphatase ; Calcium ; Cardiovascular System ; Exudates and Transudates ; Hemorrhage ; Heredity ; Macular Degeneration ; Pelvic Bones ; Phosphorus ; Pseudoxanthoma Elasticum ; Retina ; Retinaldehyde ; Skull

A 54-year-old farmer, Korean, was first seen in March of 1965, with complaints of frontal headache and ocular pain, proptosis, and blindness OD of 5 months duration. The onset was insidious. Past history and family history were not contributory. On examination, left eye was within normal limit. Right eye was displaced down- and in ward and there was moderate proptosis (about 6mm. of exophthalmos). The upper lid was partially ptotic and immobile. The ocular motility was markedly limited to those directions of lateral, upper lateral and lower lateral and moderately to the directions of the rest. Pupil was mydriatic. No mass could be felt in the orbital region. Funduscopic examination revealed pallor optic disc. There were neither papilledema nor retinal fold. X-ray films of chest, skull and optic foramen were negative except inactive signs of old tuberculosis of chest. In March of 1965, attempting to obtain a biopsy, the author adopted the Kronlein's approach by which a white-gray firm mass located in the retrobulbar space, enclosing the optic nerve firmly was taken out. For the mass was diagnosed as sclerosing angioendothelioma, irradiations of X-ray was recommended. About 7 months later, in October of 1965, the patient readmitted and then exenteration of the orbital contents was carried out. The tumor mass was attached firmly to the orbital wall at the apex and the posterior part with a considerable bony destruction. The mass taken out was a rather soft mass measuring 4 by 4 by 4 cm, and its cut surface was homogenously gray with mottled surface. of necrotic and hemorrhagic areas. Histologicatly, the mass was composed of pleomorphic bizzarre cells with hyperchromatic, abnormally mitotic nuclei, which are freely floating in alveolar lumina surrounded by well vacularized scanty fibrous septa. Cross striations could be rarely be found in high power field. Pathological diagnosis confirmed as alveolar rhabdomyosarcoma. It is suggestive that early loss of vision is caused by an optic atrophy due to direct pressure by the tumor.
Biopsy ; Blindness ; Diagnosis ; Exophthalmos ; Headache ; Humans ; Middle Aged ; Optic Atrophy ; Optic Nerve ; Orbit* ; Pallor ; Papilledema ; Pupil ; Retinaldehyde ; Rhabdomyosarcoma* ; Rhabdomyosarcoma, Alveolar ; Skull ; Thorax ; Tuberculosis ; X-Ray Film

A case of orbital mixed tumor is presented. The patient is a 20-year-old korean female, who had been deffered from 11 mm of exophthalmos, mild oculdar pain and visual disturbance (0.04 of left eye for about 1 year duration and accompanying congenital anterior polar cataract of the diseased eye. In this case, the occurrence is relatively in young age and its primary site is thought to be lacrimal gland. Visual disturbnce is thought to be caused rather by the anterior polar cataract than the tumor. The correlation between cataract and mixed tumor is obscure in this case.
Cataract ; Exophthalmos ; Female ; Humans ; Lacrimal Apparatus ; Orbit* ; Young Adult