1.Sinus Pericranii: A Case Report and the Literature Review.
Chang Hyun LEE ; Yoon Soo LEE ; Jeong Ho LEE ; Hyuk Gee LEE ; Kee Young RYU ; Dong Gee KANG
Korean Journal of Cerebrovascular Surgery 2009;11(4):174-178
Sinus pericranii is a rare vascular anomaly that's characterized by an extracranial vascular mass with anastomotic connections between the intracranial and extracranial systems via the diploic veins of the skull. Preoperative evaluations for making the diagnosis are important to help prevent unexpected intraoperative bleeding. We report here on a case of surgically treated sinus pericranii in a 20-year-old female following minor head trauma. The clinical manifestations, pathogenesis and managements are discussed, and we also review the relevant literature.
Craniocerebral Trauma
;
Female
;
Hemorrhage
;
Humans
;
Sinus Pericranii
;
Skull
;
Veins
;
Young Adult
2.Incarceration of the Gravid Uterus with Myoma: Report of One Patient Managed with Uterine Reduction.
Tae Gee JANG ; Min Hwan KO ; Tae Hyun LEE ; Eun Jee LEE ; Suk Yong WON
Korean Journal of Obstetrics and Gynecology 2000;43(11):2059-2061
Incarceration of the gravid uterus is a rare but serious complication of pregnancy. Reported is the case of a gravid 2, para 0, abortus 1 with known uterine subserosal myoma(5.3 x5.5cm sized) 26-year-old woman presented with acute dysuria and urinary retention. The patient was 14 weeks and 3 days pregnant and presented several week history of urinary frequency and sensation of incomplete bladder emptying. Examination revealed a retroflexed uterus with cervical opening pointing toward the anterior abdominal wall. An ultrasound revealed a thin, elongated maternal bladder and a uterus incarcerated between the sacral promontary and the pubis. The incarceration was successfully reduced by tenaculum traction of the cervical posterior lip without surgical intervention and had a normal infant of appropriate weight at term.
Abdominal Wall
;
Adult
;
Dysuria
;
Female
;
Humans
;
Infant
;
Leiomyoma
;
Lip
;
Myoma*
;
Pregnancy
;
Sensation
;
Traction
;
Ultrasonography
;
Urinary Bladder
;
Urinary Retention
;
Uterine Retroversion
;
Uterus*
3.LH-Beta Gene Analysis in Infertility Patients.
Jung Yeon KIM ; Gee Hyun PARK ; Sang Wook BAE ; Byung Suk LEE ; Yong Ho AN
Korean Journal of Obstetrics and Gynecology 2000;43(8):1389-1393
No abstract available.
Humans
;
Infertility*
;
Luteinizing Hormone, beta Subunit*
4.Studies on the Seasonal Changes in Epithelium of the Seminiferous Tubules and Serum Concentration of Testosterone , LH and FSH in the Korean Pheasant Phasianus colchicus.
Hong Hyun YANG ; In Sik KIM ; Young Hoon LEE ; Young Gee BAEK
Korean Journal of Anatomy 1997;30(3):269-284
It is highly desirable to achieve optimal reproductive performance, reliable morphological and physiological basic data of the reproductive organs. Therefore, seasonal changes in serum testosterone, LH, and FSH concentrations, and morphological changes in testicular epithelial cells were studied in the Korean native pheasant throughout the annual cycle. Mature male pheasants[14-16 months after hatching] were used in this study. The general morphological changes of the epithelia of the seminiferous tubules were observed by dibasic stain, and semithin section from Epon blocks with a phase contrast microscopy. The ultrastructural changes of the the epithelia of the seminiferous tubules were investigated by ultrathin section with transmission electron microscope. The changes in the profiles of the serum FSH, LH, and testosterone concentratioins were measured by RIA[radioimmunoassay]. The results obtained are summarized as follows : 1. There was little variation in the average diameter of the seminiferous tubules from autumn[67.13+/-5.95micrometer] to winter[68.59+/-6.07micrometer], but the highest levels were reached in spring[192.78+/-41.58micrometer]. Thereafter, the diameter decreased slowly in summer[146.57+/-43.68micrometer], then decreased significantly in autumn[67.13+/-5.95micrometer]. 2. Serum testosterne concentration was low from autumn[13.+/-7.21ng/100ml] to winter[17.39+/-13.75ng/100ml], but the highest levels were reached in spring[127.72+/-66.47 ng/100ml]. Thereafter, the concentration was lowest in autumn[13.+/-7.21ng/100ml]. 3. Serum LH concentration increased slowly and linealy from autumn[5.04+/-1.04ng/100ml] to winter[6.23+/-1.08ng/100ml], but the highest levels were reached in spring[11.3+/-3.6 ng/100ml]. Thereafter, the concentration reached the lowest level in autumn[5.04+/-1.04 ng/100ml]. 4. Serum FSH concentration was low from autumn[4.65+/-0.63ng/100ml] to winter[4.2+/-0.98ng/100ml], but the highest levels were reached in spring[17.41+/-8.35ng/100ml]. Thereafter, concentration was the lowest in autumn[4.65+/-0.63ng/100ml]. 5. The seminiferous tubules showed the onset of the spermatongenic cycle in spring but the seminiferous tubules collected in summer exhibited partially degenerative changes. 6. The cytoplasmic process of Sertoli cells of the seminiferous tubules of the pheasant were collected in summer. Many vesicles and degeneratiye changes were included but many number of spermatozoa were embedded partially in the multivesicular bodies in these processes. 7. The diameter of the seminiferous tubules of the pheasant narrowed markedly in autumn, and atrophied in winter. The spermatogonia and Sertoli cells were arranged in monolayer. 8. The myelin figures in the cytoplasmic process of Sertoli cells of the seminiferous tubules of the pheasant in autumn. The nucleus of the Sertoli cells were of a round configuration elongated and oriented perpendicularly to the basement membrane. The results obtained provide basic data for reproductive physiology and are useful for studying the male genital organs of the Korean native pheasant. Structural changes of the seminiferous epithelial cells significantly and postively correlated with serum FSH, LH. The correlation of changes in the hormonal status with alterations of Sertoli cell organells precedes the breeding season.
Basement Membrane
;
Breeding
;
Cytoplasm
;
Epithelial Cells
;
Epithelium*
;
Genitalia, Male
;
Humans
;
Male
;
Microscopy, Phase-Contrast
;
Multivesicular Bodies
;
Myelin Sheath
;
Physiology
;
Seasons*
;
Seminiferous Tubules*
;
Sertoli Cells
;
Spermatogonia
;
Spermatozoa
;
Testosterone*
5.The relationship between maternal serum and leukocyte zinc concentration and birth weight.
Sung Rim KIM ; Dae Hyun CHO ; Gee Deuk KIM ; Min Whan KOH ; Tae Hyung LEE ; Sung Ho LEE
Korean Journal of Obstetrics and Gynecology 1991;34(6):796-803
No abstract available.
Birth Weight*
;
Leukocytes*
;
Parturition*
;
Zinc*
6.A Clinical Study on Sacrospinous Ligament Suspension for Management of Pelvic Organ Prolapse.
Seul Kee LEE ; Gye Hyun NAM ; Yoon Sub SONG ; Hae Hyuk LEE ; Joon Gee JEON ; Seung Hyung KIM
Korean Journal of Obstetrics and Gynecology 2000;43(8):1336-1343
No abstract available.
Ligaments*
;
Pelvic Organ Prolapse*
7.Craniosynostosis : Updates in Radiologic Diagnosis.
Hyun Jeong KIM ; Hong Gee ROH ; Il Woo LEE
Journal of Korean Neurosurgical Society 2016;59(3):219-226
The purpose of this article is to review imaging findings and to discuss the optimal imaging methods for craniosynostosis. The discussion of imaging findings are focused on ultrasonography, plain radiography, magnetic resonance imaging and computed tomography with 3-dimensional reconstruction. We suggest a strategy for imaging work-up for the diagnosis, treatment planning and follow-up to minimize or avoid ionized radiation exposure to children by reviewing the current literature.
Child
;
Cranial Sutures
;
Craniosynostoses*
;
Diagnosis*
;
Follow-Up Studies
;
Humans
;
Magnetic Resonance Imaging
;
Radiography
;
Skull
;
Ultrasonography
8.Use of Polymyxin B Hemoperfusion in a Patient with Septic Shock and Septic Cardiomyopathy Who Was Placed on Extracorporeal Membrane Oxygen Support.
Sun Hye SHIN ; Hyun LEE ; Aeng Ja CHOI ; Kylie Hae Jin CHANG ; Gee Young SUH ; Chi Ryang CHUNG
Korean Journal of Critical Care Medicine 2016;31(2):123-128
Although shock in sepsis is usually managed successfully by conventional medical treatment, a subset of cases do not respond and may require salvage therapies such as veno-arterial extracorporeal membrane oxygenation (VA ECMO) support as well as an attempt to remove endotoxins. However, there are limited reports of attempts to remove endotoxins in patients with septic shock on VA ECMO support. We recently experienced a case of septic shock with severe myocardial injury whose hemodynamic improvement was unsatisfactory despite extracorporeal membrane oxygenation (ECMO) support. Since the cause of sepsis was acute pyelonephritis and blood cultures grew gram-negative bacilli, we additionally applied polymyxin B direct hemoperfusion (PMX-DHP) to the ECMO circuit and were able to successfully taper off vasopressors and wean off ECMO support. To the best of our knowledge, this is the first adult case in which PMX-DHP in addition to ECMO support was successfully utilized in a patient with septic shock. This case indicates that additional PMX-DHP therapy may be beneficial and technically feasible in patients with septic shock with severe myocardial injury refractory to ECMO support.
Adult
;
Cardiomyopathies*
;
Endotoxins
;
Extracorporeal Membrane Oxygenation
;
Hemodynamics
;
Hemoperfusion*
;
Humans
;
Membranes*
;
Oxygen*
;
Polymyxin B*
;
Polymyxins*
;
Pyelonephritis
;
Salvage Therapy
;
Sepsis
;
Shock
;
Shock, Septic*
9.A Comparison of the Effects of Different Types of Laryngoscope on Hemodynamics: McCoy Versus the Macintosh Blade.
Tae Soo HAN ; Jie Ae KIM ; Nam Gee PARK ; Sang Min LEE ; Hyun Sung CHO ; Ik Soo CHUNG
Korean Journal of Anesthesiology 1999;37(3):398-401
BACKGROUND: This study was designed to compare the hemodynamic changes in response to direct laryngoscopy of the McCoy blade and the Macintosh blade. METHODS: Sixty patients scheduled for elective gynecologic surgery were randomly allocated into two groups. The induction of anesthesia was done with thiopental sodium 5 mg/kg, fentanyl 2 mcg/kg, vecuronium 0.1 mg/kg. When the train of four arrived came at 0/4, the vocal cords were visualized with either the McCoy or the Macintosh laryngoscope blade for 10 seconds. Heart rate and blood pressure were recorded at 1 minute intervals for 5 minutes. RESULTS: Laryngoscopy caused significant increases in arterial blood pressure in both groups, while it had no effect on heart rate in either group. There were no significant differences in blood pressure and heart rate responses to laryngoscopy in the blades. CONCLUSIONS: The McCoy and the Macintosh blade show similar changes in heart rate and blood pressure after laryngoscopy.
Anesthesia
;
Arterial Pressure
;
Blood Pressure
;
Female
;
Fentanyl
;
Gynecologic Surgical Procedures
;
Heart Rate
;
Hemodynamics*
;
Humans
;
Laryngoscopes*
;
Laryngoscopy
;
Thiopental
;
Vecuronium Bromide
;
Vocal Cords
10.Anchorage Dependence and Cancer Metastasis
Dong Ki LEE ; Jongwook OH ; Hyun Woo PARK ; Heon Yung GEE
Journal of Korean Medical Science 2024;39(19):e156-
The process of cancer metastasis is dependent on the cancer cells’ capacity to detach from the primary tumor, endure in a suspended state, and establish colonies in other locations.Anchorage dependence, which refers to the cells’ reliance on attachment to the extracellular matrix (ECM), is a critical determinant of cellular shape, dynamics, behavior, and, ultimately, cell fate in nonmalignant and cancer cells. Anchorage-independent growth is a characteristic feature of cells resistant to anoikis, a programmed cell death process triggered by detachment from the ECM. This ability to grow and survive without attachment to a substrate is a crucial stage in the progression of metastasis. The recently discovered phenomenon named “adherent-to-suspension transition (AST)” alters the requirement for anchoring and enhances survival in a suspended state. AST is controlled by four transcription factors (IKAROS family zinc finger 1, nuclear factor erythroid 2, BTG anti-proliferation factor 2, and interferon regulatory factor 8) and can detach cells without undergoing the typical epithelialmesenchymal transition. Notably, AST factors are highly expressed in circulating tumor cells compared to their attached counterparts, indicating their crucial role in the spread of cancer.Crucially, the suppression of AST substantially reduces metastasis while sparing primary tumors. These findings open up possibilities for developing targeted therapies that inhibit metastasis and emphasize the importance of AST, leading to a fundamental change in our comprehension of how cancer spreads.